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Odf2 outer dense fiber of sperm tails 2 [ Mus musculus (house mouse) ]

Gene ID: 18286, updated on 25-Nov-2021

Summary

Official Symbol
Odf2provided by MGI
Official Full Name
outer dense fiber of sperm tails 2provided by MGI
Primary source
MGI:MGI:1098824
See related
Ensembl:ENSMUSG00000026790
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AI848335; MMTEST29
Expression
Biased expression in testis adult (RPKM 224.3), cerebellum adult (RPKM 22.9) and 4 other tissues See more
Orthologs
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Genomic context

See Odf2 in Genome Data Viewer
Location:
2 B; 2 20.79 cM
Exon count:
25
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (29779026..29821758)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (29889014..29931746)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (29745240..29787266)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene microRNA 219a-2 Neighboring gene predicted gene, 54109 Neighboring gene microRNA 219b Neighboring gene cerebral endothelial cell adhesion molecule Neighboring gene RIKEN cDNA 2600006K01 gene Neighboring gene GLE1 RNA export mediator (yeast) Neighboring gene spectrin alpha, non-erythrocytic 1 Neighboring gene microRNA 6997

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables small GTPase binding ISO
Inferred from Sequence Orthology
more info
 
enables structural constituent of cytoskeleton TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in centriole-centriole cohesion ISO
Inferred from Sequence Orthology
more info
 
involved_in cilium organization ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
involved_in protein localization ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of cilium assembly ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within spermatogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
part_of centriolar subdistal appendage ISO
Inferred from Sequence Orthology
more info
 
located_in centriole IDA
Inferred from Direct Assay
more info
PubMed 
located_in centriole ISO
Inferred from Sequence Orthology
more info
PubMed 
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in centrosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in centrosome ISO
Inferred from Sequence Orthology
more info
 
located_in ciliary basal body ISO
Inferred from Sequence Orthology
more info
 
part_of ciliary transition fiber IDA
Inferred from Direct Assay
more info
PubMed 
located_in cilium IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 
located_in motile cilium IEA
Inferred from Electronic Annotation
more info
 
located_in outer dense fiber ISO
Inferred from Sequence Orthology
more info
 
located_in sperm flagellum IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
outer dense fiber protein 2
Names
84 kDa outer dense fiber protein
cenexin
outer dense fiber of sperm tails protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001113213.1NP_001106684.1  outer dense fiber protein 2 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) uses a different splice site, compared to variant 4. The resulting protein (isoform a) is shorter by 1 aa when it is compared to isoform d. Variants 1 and 6 both encode the same isoform (a).
    Source sequence(s)
    AF000968, AK143726, AK148523, AK165588, BC057001
    Consensus CDS
    CCDS50556.1
    UniProtKB/Swiss-Prot
    A3KGV1
    UniProtKB/TrEMBL
    Q3UFG2
    Related
    ENSMUSP00000109385.2, ENSMUST00000113756.8
    Conserved Domains (1) summary
    COG1196
    Location:114802
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  2. NM_001113214.1NP_001106685.1  outer dense fiber protein 2 isoform b

    See identical proteins and their annotated locations for NP_001106685.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses a different splice site and contains a different 3' end, compared to variant 4. The resulting protein (isoform b) has a shorter and distinct C-terminus when it is compared to isoform d. Variants 2 and 7 both encode the same isoform (a).
    Source sequence(s)
    AF000968, AF034105, AK168415
    Consensus CDS
    CCDS50557.1
    UniProtKB/Swiss-Prot
    A3KGV1
    Related
    ENSMUSP00000109384.2, ENSMUST00000113755.8
    Conserved Domains (1) summary
    COG1196
    Location:114446
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  3. NM_001177659.1NP_001171130.1  outer dense fiber protein 2 isoform d

    See identical proteins and their annotated locations for NP_001171130.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) encodes isoform d.
    Source sequence(s)
    AF000968, AK143726, AL928926, DV644932
    Consensus CDS
    CCDS50555.1
    UniProtKB/Swiss-Prot
    A3KGV1
    Related
    ENSMUSP00000109388.3, ENSMUST00000113759.9
    Conserved Domains (1) summary
    COG1196
    Location:114803
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  4. NM_001177661.1NP_001171132.1  outer dense fiber protein 2 isoform e

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) has multiple differences that result in a different splice site and distinct 5' and 3' ends, compared to variant 4. The encoded protein (isoform c) has shorter and distinct termini when it is compared to isoform e.
    Source sequence(s)
    AF000968, AF034105, AL928926
    Consensus CDS
    CCDS50554.1
    UniProtKB/Swiss-Prot
    A3KGV1
    UniProtKB/TrEMBL
    A3KGW0
    Related
    ENSMUSP00000109396.2, ENSMUST00000113767.8
    Conserved Domains (1) summary
    cl25732
    Location:163495
    SMC_N; RecF/RecN/SMC N terminal domain
  5. NM_001355136.1NP_001342065.1  outer dense fiber protein 2 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6), as well as variant 1, encodes isoform a.
    Source sequence(s)
    AL928926, BC057001
    Consensus CDS
    CCDS50556.1
    Related
    ENSMUSP00000049272.8, ENSMUST00000046571.14
    Conserved Domains (1) summary
    COG1196
    Location:114802
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  6. NM_001355137.1NP_001342066.1  outer dense fiber protein 2 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7), as well as variant 2, encodes isoform b.
    Source sequence(s)
    AL928926
    Consensus CDS
    CCDS50557.1
    Conserved Domains (1) summary
    COG1196
    Location:114446
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  7. NM_001355138.1NP_001342067.1  outer dense fiber protein 2 isoform f

    Status: VALIDATED

    Source sequence(s)
    AL928926
    Conserved Domains (1) summary
    cl25732
    Location:95427
    SMC_N; RecF/RecN/SMC N terminal domain
  8. NM_001369060.1NP_001355989.1  outer dense fiber protein 2 isoform g

    Status: VALIDATED

    Description
    Transcript Variant: Transcript Variant: This variant (9), encodes the longest isoform (g).
    Source sequence(s)
    AL928926
    Consensus CDS
    CCDS89461.1
    Related
    ENSMUSP00000109394.2, ENSMUST00000113765.8
    Conserved Domains (1) summary
    COG1196
    Location:119807
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  9. NM_001374179.1NP_001361108.1  outer dense fiber protein 2 isoform h

    Status: VALIDATED

    Source sequence(s)
    AL928926
    Conserved Domains (1) summary
    COG1196
    Location:72760
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  10. NM_001374180.1NP_001361109.1  outer dense fiber protein 2 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL928926
    Consensus CDS
    CCDS50556.1
    Related
    ENSMUSP00000139390.2, ENSMUST00000184845.8
    Conserved Domains (1) summary
    COG1196
    Location:114802
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  11. NM_001374181.1NP_001361110.1  outer dense fiber protein 2 isoform i

    Status: VALIDATED

    Source sequence(s)
    AL928926
    Consensus CDS
    CCDS89462.1
    Conserved Domains (1) summary
    COG1196
    Location:95783
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  12. NM_001374182.1NP_001361111.1  outer dense fiber protein 2 isoform i

    Status: VALIDATED

    Source sequence(s)
    AL928926
    Consensus CDS
    CCDS89462.1
    Related
    ENSMUSP00000109386.2, ENSMUST00000113757.8
    Conserved Domains (1) summary
    COG1196
    Location:95783
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  13. NM_013615.3NP_038643.1  outer dense fiber protein 2 isoform c

    See identical proteins and their annotated locations for NP_038643.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) has multiple differences that result in a different splice site and distinct 5' and 3' ends, compared to variant 4. The encoded protein (isoform c) has shorter and distinct termini when it is compared to isoform d.
    Source sequence(s)
    AF034105, AK168415, AL928926
    Consensus CDS
    CCDS15861.1
    UniProtKB/Swiss-Prot
    A3KGV1
    Related
    ENSMUSP00000028128.7, ENSMUST00000028128.13
    Conserved Domains (1) summary
    cl25732
    Location:100432
    SMC_N; RecF/RecN/SMC N terminal domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    29779026..29821758
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017316279.2XP_017171768.1  outer dense fiber protein 2 isoform X4

    Conserved Domains (1) summary
    COG1196
    Location:120809
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  2. XM_036159407.1XP_036015300.1  outer dense fiber protein 2 isoform X5

    Conserved Domains (1) summary
    COG1196
    Location:120808
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  3. XM_030248314.1XP_030104174.1  outer dense fiber protein 2 isoform X9

    Conserved Domains (1) summary
    COG1196
    Location:101789
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  4. XM_017316291.1XP_017171780.1  outer dense fiber protein 2 isoform X7

    UniProtKB/Swiss-Prot
    A3KGV1
    Conserved Domains (1) summary
    COG1196
    Location:114803
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  5. XM_017316301.1XP_017171790.1  outer dense fiber protein 2 isoform X12

    Conserved Domains (1) summary
    COG1196
    Location:95784
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  6. XM_036159440.1XP_036015333.1  outer dense fiber protein 2 isoform X13

    Conserved Domains (1) summary
    COG1196
    Location:95783
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  7. XM_036159428.1XP_036015321.1  outer dense fiber protein 2 isoform X8

    Conserved Domains (1) summary
    COG1196
    Location:114802
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  8. XM_017316304.1XP_017171793.1  outer dense fiber protein 2 isoform X13

    UniProtKB/Swiss-Prot
    A3KGV1
    Conserved Domains (1) summary
    COG1196
    Location:95783
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  9. XM_017316272.3XP_017171761.1  outer dense fiber protein 2 isoform X1

    Conserved Domains (1) summary
    COG1196
    Location:163852
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  10. XM_017316275.3XP_017171764.1  outer dense fiber protein 2 isoform X2

    Conserved Domains (1) summary
    COG1196
    Location:144833
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  11. XM_017316276.3XP_017171765.1  outer dense fiber protein 2 isoform X3

    Conserved Domains (1) summary
    COG1196
    Location:144832
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  12. XM_017316300.2XP_017171789.1  outer dense fiber protein 2 isoform X12

    Conserved Domains (1) summary
    COG1196
    Location:95784
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  13. XM_036159427.1XP_036015320.1  outer dense fiber protein 2 isoform X8

    Conserved Domains (1) summary
    COG1196
    Location:114802
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  14. XM_017316295.3XP_017171784.1  outer dense fiber protein 2 isoform X10

    Conserved Domains (1) summary
    COG1196
    Location:100789
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  15. XM_030248309.2XP_030104169.1  outer dense fiber protein 2 isoform X6

    Conserved Domains (1) summary
    COG1196
    Location:119807
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  16. XM_017316292.2XP_017171781.1  outer dense fiber protein 2 isoform X7

    UniProtKB/Swiss-Prot
    A3KGV1
    Conserved Domains (1) summary
    COG1196
    Location:114803
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  17. XM_036159437.1XP_036015330.1  outer dense fiber protein 2 isoform X12

    Conserved Domains (1) summary
    COG1196
    Location:95784
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  18. XM_036159412.1XP_036015305.1  outer dense fiber protein 2 isoform X7

    Conserved Domains (1) summary
    COG1196
    Location:114803
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  19. XM_017316290.3XP_017171779.1  outer dense fiber protein 2 isoform X7

    UniProtKB/Swiss-Prot
    A3KGV1
    Conserved Domains (1) summary
    COG1196
    Location:114803
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  20. XM_017316294.3XP_017171783.1  outer dense fiber protein 2 isoform X10

    Conserved Domains (1) summary
    COG1196
    Location:100789
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  21. XM_017316293.3XP_017171782.1  outer dense fiber protein 2 isoform X8

    UniProtKB/Swiss-Prot
    A3KGV1
    Conserved Domains (1) summary
    COG1196
    Location:114802
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  22. XM_017316299.3XP_017171788.1  outer dense fiber protein 2 isoform X11

    Conserved Domains (1) summary
    COG1196
    Location:100788
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  23. XM_036159408.1XP_036015301.1  outer dense fiber protein 2 isoform X6

    Conserved Domains (1) summary
    COG1196
    Location:119807
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

RNA

  1. XR_003951351.2 RNA Sequence

  2. XR_003951352.2 RNA Sequence

  3. XR_003951350.2 RNA Sequence

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