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Ppp1r14b protein phosphatase 1, regulatory inhibitor subunit 14B [ Mus musculus (house mouse) ]

Gene ID: 18938, updated on 23-Jun-2021

Summary

Official Symbol
Ppp1r14bprovided by MGI
Official Full Name
protein phosphatase 1, regulatory inhibitor subunit 14Bprovided by MGI
Primary source
MGI:MGI:107682
See related
Ensembl:ENSMUSG00000056612
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
P; PHI; PLC; Png; AOM1; PHI-1; AOM172; PLCB3N
Expression
Ubiquitous expression in whole brain E14.5 (RPKM 114.0), CNS E14 (RPKM 112.7) and 28 other tissues See more
Orthologs
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Genomic context

See Ppp1r14b in Genome Data Viewer
Location:
19; 19 A
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (6952416..6954692)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (6975048..6977324)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (7049538..7051814)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene BCL2-associated agonist of cell death Neighboring gene ATG2 autophagy related 2 homolog A pseudogene Neighboring gene phospholipase C, beta 3 Neighboring gene predicted gene, 52400 Neighboring gene uncharacterized LOC118568403 Neighboring gene predicted gene, 51400 Neighboring gene FK506 binding protein 2 Neighboring gene vascular endothelial growth factor B

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables phosphatase inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
enables protein phosphatase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
enables protein phosphatase regulator activity ISO
Inferred from Sequence Orthology
more info
 
enables protein serine/threonine phosphatase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of phosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein phosphatase 1 regulatory subunit 14B
Names
phosphatase holoenzyme inhibitor 1
phospholipase C-beta-3 neighbouring gene protein
phospholipase c neighboring

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008889.2NP_032915.2  protein phosphatase 1 regulatory subunit 14B

    See identical proteins and their annotated locations for NP_032915.2

    Status: VALIDATED

    Source sequence(s)
    BC082545, CF739461
    Consensus CDS
    CCDS29514.1
    UniProtKB/Swiss-Prot
    Q62084
    Related
    ENSMUSP00000064129.7, ENSMUST00000070850.8
    Conserved Domains (1) summary
    pfam05361
    Location:51147
    PP1_inhibitor; PKC-activated protein phosphatase-1 inhibitor

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    6952416..6954692
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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