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Prim1 DNA primase, p49 subunit [ Mus musculus (house mouse) ]

Gene ID: 19075, updated on 8-Jul-2021

Summary

Official Symbol
Prim1provided by MGI
Official Full Name
DNA primase, p49 subunitprovided by MGI
Primary source
MGI:MGI:97757
See related
Ensembl:ENSMUSG00000025395
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AI324982
Expression
Broad expression in liver E14 (RPKM 29.4), CNS E11.5 (RPKM 24.3) and 15 other tissues See more
Orthologs
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Genomic context

See Prim1 in Genome Data Viewer
Location:
10 76.39 cM; 10 D3
Exon count:
13
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (127851084..127865899)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (128015215..128030030)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (127452271..127467086)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene hydroxysteroid (17-beta) dehydrogenase 6 Neighboring gene small nuclear ribonucleoprotein D2 pseudogene Neighboring gene nascent polypeptide-associated complex alpha polypeptide Neighboring gene prostaglandin E synthase 3 Neighboring gene predicted gene, 47438

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC107288

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA primase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables DNA primase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA primase activity ISO
Inferred from Sequence Orthology
more info
 
enables DNA-directed 5'-3' RNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 
enables magnesium ion binding ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotidyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables ribonucleotide binding ISO
Inferred from Sequence Orthology
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within DNA replication IEA
Inferred from Electronic Annotation
more info
 
involved_in DNA replication, synthesis of RNA primer IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in DNA replication, synthesis of RNA primer IDA
Inferred from Direct Assay
more info
PubMed 
involved_in DNA replication, synthesis of RNA primer ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of alpha DNA polymerase:primase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of alpha DNA polymerase:primase complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of alpha DNA polymerase:primase complex ISO
Inferred from Sequence Orthology
more info
 
part_of primosome complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
DNA primase small subunit
Names
DNA primase 49 kDa subunit
p49
NP_032947.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008921.2NP_032947.1  DNA primase small subunit

    See identical proteins and their annotated locations for NP_032947.1

    Status: PROVISIONAL

    Source sequence(s)
    AC131120
    Consensus CDS
    CCDS36086.1
    UniProtKB/Swiss-Prot
    P20664
    UniProtKB/TrEMBL
    Q5FW94
    Related
    ENSMUSP00000026461.8, ENSMUST00000026461.8
    Conserved Domains (1) summary
    cd04860
    Location:26343
    AE_Prim_S; AE_Prim_S: primase domain similar to that found in the small subunit of archaeal and eukaryotic (A/E) DNA primases. Primases are DNA-dependent RNA polymerases which synthesis the short RNA primers required for DNA replication. In addition to its ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    127851084..127865899
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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