Nlgn1 neuroligin 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Nlgn1provided by MGI
Official Full Name: neuroligin 1provided by MGI
Primary source: MGI:MGI:2179435
See related: Ensembl:ENSMUSG00000063887 AllianceGenome:MGI:2179435
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: NL1; Nlg1; mKIAA1070; 6330415N05Rik
Summary: Enables neurexin family protein binding activity. Involved in several processes, including positive regulation of transport; synapse organization; and synaptic vesicle cycle. Acts upstream of or within several processes, including positive regulation of synapse assembly; regulation of respiratory gaseous exchange by nervous system process; and synapse organization. Located in external side of plasma membrane and synapse. Is integral component of plasma membrane. Part of receptor complex. Is active in glutamatergic synapse. Is expressed in blood vessel and brain. Used to study autism spectrum disorder. Orthologous to human NLGN1 (neuroligin 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in cortex adult (RPKM 4.2), CNS E18 (RPKM 4.1) and 6 other tissues See more
Orthologs: human all
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Genomic context

Location:: 3 A3; 3 10.38 cM

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	3	NC_000069.7 (25475972..26387504, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	3	NC_000069.6 (25421808..26332866, complement)

Chromosome 3 - NC_000069.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Preoperative environment enrichment preserved neuroligin 1 expression possibly via epigenetic regulation to reduce postoperative cognitive dysfunction in mice.
Title: Preoperative environment enrichment preserved neuroligin 1 expression possibly via epigenetic regulation to reduce postoperative cognitive dysfunction in mice.
Tumoral Neuroligin 1 Promotes Cancer-Nerve Interactions and Synergizes with the Glial Cell Line-Derived Neurotrophic Factor.
Title: Tumoral Neuroligin 1 Promotes Cancer-Nerve Interactions and Synergizes with the Glial Cell Line-Derived Neurotrophic Factor.
Dopaminergic neurons establish a distinctive axonal arbor with a majority of non-synaptic terminals.
Title: Dopaminergic neurons establish a distinctive axonal arbor with a majority of non-synaptic terminals.
A molecular insight into the dissociable regulation of associative learning and motivation by the synaptic protein neuroligin-1.
Title: A molecular insight into the dissociable regulation of associative learning and motivation by the synaptic protein neuroligin-1.
Alternative splicing at neuroligin site A regulates glycan interaction and synaptogenic activity.
Title: Alternative splicing at neuroligin site A regulates glycan interaction and synaptogenic activity.
A phosphorylation-dependent molecular mechanism that regulates NLGN1 and PSD-95 binding.
Title: PSD-95 binding dynamically regulates NLGN1 trafficking and function.
Nlgn1 performs two key functions in excitatory synapses by distinct molecular mechanisms. NMDA receptor-dependent long term potentiation (LTP) requires trans-synaptic binding of postsynaptic neuroligin-1 to presynaptic beta-neurexins but not the cytoplasmic sequences of neuroligins. Postsynaptic NMDA receptor-mediated responses involve a neurexin-independent mechanism that requires the neuroligin-1 cytoplasmic sequences.
Title: Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways.
This study provides a novel approach to understand the molecular basis of Fragile X syndrome by linking the dysregulated synaptic expression of NLGNs with FMRP
Title: Neuroligin 1, 2, and 3 Regulation at the Synapse: FMRP-Dependent Translation and Activity-Induced Proteolytic Cleavage.
To characterize the possible contribution of NLGN1 to inflammatory pain, the present study analyzed the changes of NLGN1 expression after intraplantar injection of complete Freund's adjuvant (CFA). Our data revealed an activity-dependent recruitment of NLGN1 into synapses, which was essential for NMDAR hyperfunction and pain hypersensitivity.
Title: Activity-dependent Synaptic Recruitment of Neuroligin 1 in Spinal Dorsal Horn Contributed to Inflammatory Pain.
Results demonstrate that NLG1 regulates hippocampal long-term depression (LTD) in a gene dosage-dependent manner. Thus, NLG1+/-, but not NLG1-/- mice, show impaired NMDAR-LTD and elevated mGluR-LTD. In addition, NLG1+/- mice exhibit autistic-like behavior including increased grooming and impairments in social recognition and contextual fear memory.
Title: Regulation of hippocampal long term depression by Neuroligin 1.

Submit: New GeneRIF Correction See all GeneRIFs (45)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (3) 1 citation
Endonuclease-mediated (3) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

D3Mit92 (e-PCR), detects polymorphism
- UniSTS:129863

D3Mit92.1 (e-PCR), detects polymorphism
- UniSTS:129864

BB392043 (e-PCR)
- UniSTS:207467

BB391041 (e-PCR)
- UniSTS:207469

RH127137 (e-PCR)
- UniSTS:207470

15.MMHAP14FLE3.seq (e-PCR)
- UniSTS:123250

21.MMHAP50FRG9.seq (e-PCR)
- UniSTS:123524

BB179718 (e-PCR)
- UniSTS:185526

NoName (e-PCR)
- UniSTS:224698

12.MMHAP85FRD9.seq (e-PCR)
- UniSTS:123135

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables PDZ domain binding	ISO Inferred from Sequence Orthology more info
enables cell adhesion molecule binding	ISO Inferred from Sequence Orthology more info
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables neurexin family protein binding	IBA Inferred from Biological aspect of Ancestor more info
enables neurexin family protein binding	IMP Inferred from Mutant Phenotype more info	PubMed
enables neurexin family protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables neurexin family protein binding	ISO Inferred from Sequence Orthology more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein-containing complex binding	ISO Inferred from Sequence Orthology more info
enables scaffold protein binding	ISO Inferred from Sequence Orthology more info
enables signaling receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables signaling receptor activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in AMPA glutamate receptor clustering	IDA Inferred from Direct Assay more info	PubMed
involved_in AMPA glutamate receptor clustering	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in AMPA glutamate receptor clustering	ISO Inferred from Sequence Orthology more info
involved_in NMDA glutamate receptor clustering	ISO Inferred from Sequence Orthology more info
involved_in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	IDA Inferred from Direct Assay more info	PubMed
involved_in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	ISO Inferred from Sequence Orthology more info
involved_in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	NAS Non-traceable Author Statement more info	PubMed
acts_upstream_of_or_within cell adhesion	IEA Inferred from Electronic Annotation more info
involved_in cell-cell adhesion involved in synapse maturation	NAS Non-traceable Author Statement more info	PubMed
involved_in cellular response to calcium ion	ISO Inferred from Sequence Orthology more info
involved_in chemical synaptic transmission	IBA Inferred from Biological aspect of Ancestor more info
involved_in cytoskeletal matrix organization at active zone	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cytoskeletal matrix organization at active zone	ISO Inferred from Sequence Orthology more info
involved_in establishment of protein localization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in excitatory synapse assembly	IDA Inferred from Direct Assay more info	PubMed
involved_in excitatory synapse assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IDA Inferred from Direct Assay more info	PubMed
NOT involved_in inhibitory postsynaptic potential	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in long-term synaptic potentiation	ISO Inferred from Sequence Orthology more info
involved_in maintenance of synapse structure	NAS Non-traceable Author Statement more info	PubMed
involved_in modulation of chemical synaptic transmission	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within modulation of chemical synaptic transmission	IGI Inferred from Genetic Interaction more info	PubMed
involved_in modulation of chemical synaptic transmission	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of dendritic spine morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of dendritic spine morphogenesis	ISO Inferred from Sequence Orthology more info
involved_in nervous system development	IDA Inferred from Direct Assay more info	PubMed
involved_in nervous system development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in nervous system development	ISO Inferred from Sequence Orthology more info
involved_in neurexin clustering involved in presynaptic membrane assembly	IDA Inferred from Direct Assay more info	PubMed
involved_in neuron cell-cell adhesion	IBA Inferred from Biological aspect of Ancestor more info
involved_in neuron cell-cell adhesion	IDA Inferred from Direct Assay more info	PubMed
involved_in neuron cell-cell adhesion	ISO Inferred from Sequence Orthology more info
involved_in neuron cell-cell adhesion	NAS Non-traceable Author Statement more info	PubMed
involved_in neuron projection arborization	ISO Inferred from Sequence Orthology more info
involved_in neuron projection development	ISO Inferred from Sequence Orthology more info
involved_in neuron projection morphogenesis	NAS Non-traceable Author Statement more info	PubMed
involved_in positive regulation of circadian sleep/wake cycle, wakefulness	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of dendritic spine development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of dendritic spine development	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of excitatory postsynaptic potential	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of excitatory postsynaptic potential	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of excitatory postsynaptic potential	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of filopodium assembly	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of intracellular signal transduction	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of neuromuscular synaptic transmission	NAS Non-traceable Author Statement more info	PubMed
involved_in positive regulation of neuron projection development	NAS Non-traceable Author Statement more info	PubMed
involved_in positive regulation of presynaptic active zone assembly	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of protein localization to synapse	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of ruffle assembly	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of synapse assembly	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within positive regulation of synapse assembly	ISO Inferred from Sequence Orthology more info	PubMed
involved_in positive regulation of synapse assembly	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of synaptic transmission, GABAergic	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of synaptic transmission, GABAergic	NAS Non-traceable Author Statement more info	PubMed
involved_in positive regulation of synaptic transmission, glutamatergic	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of synaptic transmission, glutamatergic	NAS Non-traceable Author Statement more info	PubMed
involved_in positive regulation of synaptic vesicle clustering	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of synaptic vesicle endocytosis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of synaptic vesicle endocytosis	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of synaptic vesicle exocytosis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of synaptic vesicle exocytosis	ISO Inferred from Sequence Orthology more info
involved_in postsynaptic density protein 95 clustering	IDA Inferred from Direct Assay more info	PubMed
involved_in postsynaptic density protein 95 clustering	ISO Inferred from Sequence Orthology more info
involved_in postsynaptic membrane assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in postsynaptic membrane assembly	IDA Inferred from Direct Assay more info	PubMed
involved_in postsynaptic specialization assembly	IDA Inferred from Direct Assay more info	PubMed
involved_in postsynaptic specialization assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in presynaptic membrane assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in presynaptic membrane assembly	IDA Inferred from Direct Assay more info	PubMed
involved_in presynaptic membrane assembly	ISO Inferred from Sequence Orthology more info
involved_in protein localization to synapse	IDA Inferred from Direct Assay more info	PubMed
involved_in protein targeting	ISO Inferred from Sequence Orthology more info
involved_in receptor localization to synapse	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of NMDA receptor activity	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of NMDA receptor activity	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of NMDA receptor activity	ISO Inferred from Sequence Orthology more info
involved_in regulation of neuron differentiation	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of postsynaptic density assembly	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of postsynaptic density assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of presynapse organization	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of respiratory gaseous exchange by nervous system process	IGI Inferred from Genetic Interaction more info	PubMed
involved_in retrograde trans-synaptic signaling by trans-synaptic protein complex	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within rhythmic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of synapse assembly	IDA Inferred from Direct Assay more info	PubMed
involved_in synapse assembly	IDA Inferred from Direct Assay more info	PubMed
involved_in synapse assembly	ISO Inferred from Sequence Orthology more info
involved_in synapse assembly	NAS Non-traceable Author Statement more info	PubMed
involved_in synapse maturation	NAS Non-traceable Author Statement more info	PubMed
acts_upstream_of_or_within synapse organization	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within synapse organization	ISO Inferred from Sequence Orthology more info	PubMed
involved_in synaptic membrane adhesion	IDA Inferred from Direct Assay more info	PubMed
involved_in synaptic membrane adhesion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in synaptic vesicle clustering	IDA Inferred from Direct Assay more info	PubMed
involved_in synaptic vesicle clustering	ISO Inferred from Sequence Orthology more info
involved_in synaptic vesicle endocytosis	IBA Inferred from Biological aspect of Ancestor more info
involved_in synaptic vesicle targeting	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in synaptic vesicle transport	ISO Inferred from Sequence Orthology more info
involved_in terminal button organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in terminal button organization	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in GABA-ergic synapse	NAS Non-traceable Author Statement more info	PubMed
located_in Golgi apparatus	ISO Inferred from Sequence Orthology more info
is_active_in cell surface	IBA Inferred from Biological aspect of Ancestor more info
located_in cell surface	IDA Inferred from Direct Assay more info	PubMed
located_in cell surface	ISO Inferred from Sequence Orthology more info
located_in dendrite	ISO Inferred from Sequence Orthology more info
located_in dendritic shaft	ISO Inferred from Sequence Orthology more info
located_in dendritic spine	ISO Inferred from Sequence Orthology more info
located_in excitatory synapse	IC Inferred by Curator more info	PubMed
located_in excitatory synapse	NAS Non-traceable Author Statement more info	PubMed
located_in external side of plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in extracellular region	IEA Inferred from Electronic Annotation more info
located_in filopodium tip	ISO Inferred from Sequence Orthology more info
is_active_in glutamatergic synapse	IDA Inferred from Direct Assay more info	PubMed
is_active_in glutamatergic synapse	IMP Inferred from Mutant Phenotype more info	PubMed
is_active_in glutamatergic synapse	ISO Inferred from Sequence Orthology more info
located_in glutamatergic synapse	NAS Non-traceable Author Statement more info	PubMed
located_in inhibitory synapse	NAS Non-traceable Author Statement more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in neuromuscular junction	NAS Non-traceable Author Statement more info	PubMed
located_in neuron to neuron synapse	NAS Non-traceable Author Statement more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IMP Inferred from Mutant Phenotype more info	PubMed
located_in plasma membrane	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	NAS Non-traceable Author Statement more info	PubMed
is_active_in postsynaptic specialization membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in postsynaptic specialization membrane	ISO Inferred from Sequence Orthology more info
located_in postsynaptic specialization membrane	ISO Inferred from Sequence Orthology more info
part_of protein complex involved in cell-cell adhesion	EXP Inferred from Experiment more info	PubMed
part_of protein complex involved in cell-cell adhesion	ISO Inferred from Sequence Orthology more info
part_of receptor complex	IDA Inferred from Direct Assay more info	PubMed
is_active_in synapse	IBA Inferred from Biological aspect of Ancestor more info
located_in synapse	IDA Inferred from Direct Assay more info	PubMed
located_in synapse	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: neuroligin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001163387.2 → NP_001156859.1 neuroligin-1 isoform 2

See identical proteins and their annotated locations for NP_001156859.1

Status: VALIDATED

Source sequence(s)

AC099863, AC100381, AC127365

Consensus CDS

CCDS50874.1

UniProtKB/TrEMBL

E9QK34, Q4KMN5

Related

ENSMUSP00000142086.2, ENSMUST00000191835.2

Conserved Domains (1) summary

pfam00135
Location:52 → 597

COesterase; Carboxylesterase family
NM_001357095.1 → NP_001344024.1 neuroligin-1 isoform 3

Status: VALIDATED

Source sequence(s)

AC099863, AC100381, AC127365

UniProtKB/TrEMBL

Q4KMN5

Conserved Domains (1) summary

pfam00135
Location:52 → 626

COesterase; Carboxylesterase family
NM_001357096.1 → NP_001344025.1 neuroligin-1 isoform 4

Status: VALIDATED

Source sequence(s)

AC099863, AC100381, AC127365

UniProtKB/TrEMBL

Q4KMN5

Conserved Domains (1) summary

pfam00135
Location:52 → 606

COesterase; Carboxylesterase family
NM_001357097.1 → NP_001344026.1 neuroligin-1 isoform 4

Status: VALIDATED

Source sequence(s)

AC099863, AC100381, AC127365

UniProtKB/TrEMBL

Q4KMN5

Conserved Domains (1) summary

pfam00135
Location:52 → 606

COesterase; Carboxylesterase family
NM_138666.4 → NP_619607.2 neuroligin-1 isoform 1 precursor

See identical proteins and their annotated locations for NP_619607.2

Status: VALIDATED

Source sequence(s)

AC099863, AC100381, AC123660, AC127365

Consensus CDS

CCDS17268.1

UniProtKB/Swiss-Prot

Q99K10

UniProtKB/TrEMBL

Q4KMN5

Related

ENSMUSP00000142200.2, ENSMUST00000193603.6

Conserved Domains (1) summary

pfam00135
Location:52 → 626

COesterase; Carboxylesterase family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000069.7 Reference GRCm39 C57BL/6J

Range

25475972..26387504 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_036162947.1 → XP_036018840.1 neuroligin-1 isoform X3

UniProtKB/Swiss-Prot

Q99K10

UniProtKB/TrEMBL

Q4KMN5

Conserved Domains (1) summary

pfam00135
Location:52 → 626

COesterase; Carboxylesterase family
XM_036162946.1 → XP_036018839.1 neuroligin-1 isoform X2

UniProtKB/TrEMBL

Q4KMN5

Conserved Domains (1) summary

pfam00135
Location:52 → 637

COesterase; Carboxylesterase family
XM_006535415.3 → XP_006535478.1 neuroligin-1 isoform X1

See identical proteins and their annotated locations for XP_006535478.1

UniProtKB/TrEMBL

Q4KMN5

Conserved Domains (1) summary

pfam00135
Location:53 → 646

COesterase; Carboxylesterase family
XM_006535416.4 → XP_006535479.1 neuroligin-1 isoform X1

See identical proteins and their annotated locations for XP_006535479.1

UniProtKB/TrEMBL

Q4KMN5

Conserved Domains (1) summary

pfam00135
Location:53 → 646

COesterase; Carboxylesterase family
XM_006535419.4 → XP_006535482.1 neuroligin-1 isoform X1

See identical proteins and their annotated locations for XP_006535482.1

UniProtKB/TrEMBL

Q4KMN5

Conserved Domains (1) summary

pfam00135
Location:53 → 646

COesterase; Carboxylesterase family
XM_036162950.1 → XP_036018843.1 neuroligin-1 isoform X3

UniProtKB/Swiss-Prot

Q99K10

UniProtKB/TrEMBL

Q4KMN5

Conserved Domains (1) summary

pfam00135
Location:52 → 626

COesterase; Carboxylesterase family
XM_036162955.1 → XP_036018848.1 neuroligin-1 isoform X9

UniProtKB/TrEMBL

Q3UUP2

Conserved Domains (1) summary

pfam00135
Location:1 → 431

COesterase; Carboxylesterase family
XM_030252466.2 → XP_030108326.1 neuroligin-1 isoform X1

UniProtKB/TrEMBL

Q4KMN5

Conserved Domains (1) summary

pfam00135
Location:53 → 646

COesterase; Carboxylesterase family
XM_036162953.1 → XP_036018846.1 neuroligin-1 isoform X7

UniProtKB/TrEMBL

E9QK34, Q4KMN5

Conserved Domains (1) summary

pfam00135
Location:52 → 597

COesterase; Carboxylesterase family
XM_036162951.1 → XP_036018844.1 neuroligin-1 isoform X6

UniProtKB/TrEMBL

Q4KMN5

Conserved Domains (1) summary

pfam00135
Location:52 → 606

COesterase; Carboxylesterase family
XM_036162948.1 → XP_036018841.1 neuroligin-1 isoform X4

UniProtKB/TrEMBL

Q4KMN5

Conserved Domains (1) summary

pfam00135
Location:52 → 626

COesterase; Carboxylesterase family
XM_006535418.5 → XP_006535481.1 neuroligin-1 isoform X1

See identical proteins and their annotated locations for XP_006535481.1

UniProtKB/TrEMBL

Q4KMN5

Conserved Domains (1) summary

pfam00135
Location:53 → 646

COesterase; Carboxylesterase family
XM_036162954.1 → XP_036018847.1 neuroligin-1 isoform X8

UniProtKB/TrEMBL

Q4KMN5

Conserved Domains (1) summary

pfam00135
Location:52 → 555

COesterase; Carboxylesterase family
XM_006535425.5 → XP_006535488.1 neuroligin-1 isoform X7

See identical proteins and their annotated locations for XP_006535488.1

UniProtKB/TrEMBL

E9QK34, Q4KMN5

Conserved Domains (1) summary

pfam00135
Location:52 → 597

COesterase; Carboxylesterase family
XM_006535424.5 → XP_006535487.1 neuroligin-1 isoform X6

UniProtKB/TrEMBL

Q4KMN5

Conserved Domains (1) summary

pfam00135
Location:52 → 606

COesterase; Carboxylesterase family
XM_006535423.5 → XP_006535486.1 neuroligin-1 isoform X5

UniProtKB/TrEMBL

Q4KMN5

Conserved Domains (1) summary

pfam00135
Location:53 → 617

COesterase; Carboxylesterase family
XM_006535422.5 → XP_006535485.1 neuroligin-1 isoform X4

UniProtKB/TrEMBL

Q4KMN5

Conserved Domains (1) summary

pfam00135
Location:52 → 626

COesterase; Carboxylesterase family
XM_006535421.5 → XP_006535484.1 neuroligin-1 isoform X2

UniProtKB/TrEMBL

Q4KMN5

Conserved Domains (1) summary

pfam00135
Location:52 → 637

COesterase; Carboxylesterase family
XM_036162952.1 → XP_036018845.1 neuroligin-1 isoform X7

UniProtKB/TrEMBL

E9QK34, Q4KMN5

Conserved Domains (1) summary

pfam00135
Location:52 → 597

COesterase; Carboxylesterase family
XM_036162949.1 → XP_036018842.1 neuroligin-1 isoform X3

UniProtKB/Swiss-Prot

Q99K10

UniProtKB/TrEMBL

Q4KMN5

Related

ENSMUSP00000074565.5, ENSMUST00000075054.10

Conserved Domains (1) summary

pfam00135
Location:52 → 626

COesterase; Carboxylesterase family
XM_006535420.5 → XP_006535483.1 neuroligin-1 isoform X1

See identical proteins and their annotated locations for XP_006535483.1

UniProtKB/TrEMBL

Q4KMN5

Conserved Domains (1) summary

pfam00135
Location:53 → 646

COesterase; Carboxylesterase family