Format

Send to:

Choose Destination

Ptk2b PTK2 protein tyrosine kinase 2 beta [ Mus musculus (house mouse) ]

Gene ID: 19229, updated on 23-Jun-2021

Summary

Official Symbol
Ptk2bprovided by MGI
Official Full Name
PTK2 protein tyrosine kinase 2 betaprovided by MGI
Primary source
MGI:MGI:104908
See related
Ensembl:ENSMUSG00000059456
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
PYK; Raf; CAKB; FAK2; PYK2; CADTK; CAKbe; FADK2; Raftk; CAKbeta; E430023O05Rik
Expression
Broad expression in frontal lobe adult (RPKM 53.4), cortex adult (RPKM 51.8) and 21 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Ptk2b in Genome Data Viewer
Location:
14 D1; 14 34.36 cM
Exon count:
35
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (66390706..66518549, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (66153257..66281100, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (66772094..66899889, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene epoxide hydrolase 2, cytoplasmic Neighboring gene cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) Neighboring gene predicted gene, 52098 Neighboring gene predicted gene, 52099 Neighboring gene RIKEN cDNA 1700001G11 gene Neighboring gene tripartite motif-containing 35 Neighboring gene predicted gene, 41183

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables 3-phosphoinositide-dependent protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables calmodulin-dependent protein kinase activity ISO
Inferred from Sequence Orthology
more info
 
enables enzyme binding ISO
Inferred from Sequence Orthology
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables non-membrane spanning protein tyrosine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables non-membrane spanning protein tyrosine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables non-membrane spanning protein tyrosine kinase activity ISO
Inferred from Sequence Orthology
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein C-terminus binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein tyrosine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
 
enables signaling receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin protein ligase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in MAPK cascade ISO
Inferred from Sequence Orthology
more info
 
involved_in actin filament organization ISO
Inferred from Sequence Orthology
more info
 
involved_in activation of GTPase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in activation of Janus kinase activity ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within adaptive immune response IEA
Inferred from Electronic Annotation
more info
 
involved_in angiogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in angiogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in blood vessel endothelial cell migration ISO
Inferred from Sequence Orthology
more info
 
involved_in bone resorption IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cell adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cell surface receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within cellular response to fluid shear stress IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cellular response to retinoic acid ISO
Inferred from Sequence Orthology
more info
 
involved_in chemokine-mediated signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in endothelin receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in epidermal growth factor receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in epidermal growth factor receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in focal adhesion assembly ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within immune system process IEA
Inferred from Electronic Annotation
more info
 
involved_in innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in integrin-mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in long-term synaptic depression ISO
Inferred from Sequence Orthology
more info
 
involved_in long-term synaptic potentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in marginal zone B cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of bone mineralization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of cell population proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of muscle cell apoptotic process ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of myeloid cell differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of neuron apoptotic process ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of ossification ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of potassium ion transport ISO
Inferred from Sequence Orthology
more info
 
involved_in neuron projection development ISO
Inferred from Sequence Orthology
more info
 
involved_in oocyte maturation ISO
Inferred from Sequence Orthology
more info
 
involved_in peptidyl-tyrosine autophosphorylation ISO
Inferred from Sequence Orthology
more info
 
involved_in peptidyl-tyrosine phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in peptidyl-tyrosine phosphorylation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of B cell chemotaxis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of DNA biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of ERK1 and ERK2 cascade ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of JNK cascade ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of JUN kinase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of actin filament polymerization ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of angiogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of cell growth ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cell migration ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cell population proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of cell population proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cell-matrix adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cellular protein metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cytosolic calcium ion concentration ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of endothelial cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of endothelial cell migration ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of excitatory postsynaptic potential ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of neuron projection development ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of nitric oxide biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of nitric-oxide synthase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of nitric-oxide synthase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of peptidyl-tyrosine phosphorylation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of phosphatidylinositol 3-kinase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of protein kinase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of protein kinase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of reactive oxygen species metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of synaptic transmission, glutamatergic ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of translation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of ubiquitin-dependent protein catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within protein phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of NMDA receptor activity ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of actin cytoskeleton reorganization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of angiogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of bone mineralization IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of cGMP-mediated signaling IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of calcium-mediated signaling IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of cell adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of cell shape IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of cell shape ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of establishment of cell polarity IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of inositol trisphosphate biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of leukocyte chemotaxis IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of macrophage chemotaxis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of nitric oxide biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of release of sequestered calcium ion into cytosol IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of ubiquitin-dependent protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in response to hydrogen peroxide ISO
Inferred from Sequence Orthology
more info
 
involved_in signal complex assembly IEA
Inferred from Electronic Annotation
more info
 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 
involved_in sprouting angiogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in stress fiber assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in transmembrane receptor protein tyrosine kinase signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in tumor necrosis factor-mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in vascular endothelial growth factor receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in vascular endothelial growth factor receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of NMDA selective glutamate receptor complex ISO
Inferred from Sequence Orthology
more info
 
located_in apical dendrite ISO
Inferred from Sequence Orthology
more info
 
located_in axon ISO
Inferred from Sequence Orthology
more info
 
located_in cell body ISO
Inferred from Sequence Orthology
more info
 
located_in cell cortex ISO
Inferred from Sequence Orthology
more info
 
located_in cell junction IEA
Inferred from Electronic Annotation
more info
 
located_in cell projection ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in dendrite ISO
Inferred from Sequence Orthology
more info
 
is_active_in dendritic spine IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in dendritic spine ISO
Inferred from Sequence Orthology
more info
 
is_active_in extrinsic component of cytoplasmic side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in focal adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in focal adhesion ISO
Inferred from Sequence Orthology
more info
 
located_in glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
 
located_in growth cone ISO
Inferred from Sequence Orthology
more info
 
located_in lamellipodium ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane raft ISO
Inferred from Sequence Orthology
more info
 
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in postsynapse ISO
Inferred from Sequence Orthology
more info
 
located_in postsynaptic density ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein-tyrosine kinase 2-beta
Names
CAK-beta
calcium-dependent tyrosine kinase
calcium-regulated non-receptor proline-rich tyrosine kinase
cell adhesion kinase beta
cellular adhesion kinase beta
focal adhesion kinase 2
proline-rich tyrosine kinase 2
related adhesion focal tyrosine kinase
NP_001155837.1
NP_001155838.1
NP_001347162.1
NP_766086.2
XP_017171415.1
XP_017171416.1
XP_017171417.1
XP_017171418.1
XP_017171419.1
XP_036014417.1
XP_036014418.1
XP_036014419.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001162365.1NP_001155837.1  protein-tyrosine kinase 2-beta isoform 2

    See identical proteins and their annotated locations for NP_001155837.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region compared to variant 1. This results in a shorter protein (isoform 2) compared to isoform 1.
    Source sequence(s)
    AC140329, AK150105, BY204086, CD775714
    Consensus CDS
    CCDS49525.1
    UniProtKB/TrEMBL
    Q3UDE9
    Related
    ENSMUSP00000106750.2, ENSMUST00000111121.2
    Conserved Domains (6) summary
    cd05056
    Location:418687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00219
    Location:425679
    TyrKc; Tyrosine kinase, catalytic domain
    smart00295
    Location:41254
    B41; Band 4.1 homologues
    cd13190
    Location:261368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    cd14473
    Location:150254
    FERM_B-lobe; FERM domain B-lobe
    pfam03623
    Location:868997
    Focal_AT; Focal adhesion targeting region
  2. NM_001162366.2NP_001155838.1  protein-tyrosine kinase 2-beta isoform 1

    See identical proteins and their annotated locations for NP_001155838.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Variants 1 and 4 encode the same isoform (1).
    Source sequence(s)
    AC140329, AI181574, AK150105, BY203814, BY206153, CD775714
    Consensus CDS
    CCDS49526.1
    UniProtKB/Swiss-Prot
    Q9QVP9
    UniProtKB/TrEMBL
    K7QD41, Q3UDE9
    Related
    ENSMUSP00000022622.8, ENSMUST00000022622.14
    Conserved Domains (4) summary
    cd05056
    Location:418687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:41254
    B41; Band 4.1 homologues
    cd13190
    Location:261368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:8721001
    Focal_AT; Focal adhesion targeting region
  3. NM_001360233.1NP_001347162.1  protein-tyrosine kinase 2-beta isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1 and 4 encode the same isoform (1).
    Source sequence(s)
    AC140329, AI181574, AK150105, BY203814, CD775714
    Consensus CDS
    CCDS49526.1
    Related
    ENSMUSP00000137008.2, ENSMUST00000178730.8
    Conserved Domains (4) summary
    cd05056
    Location:418687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:41254
    B41; Band 4.1 homologues
    cd13190
    Location:261368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:8721001
    Focal_AT; Focal adhesion targeting region
  4. NM_172498.3NP_766086.2  protein-tyrosine kinase 2-beta isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1. This results in a shorter protein (isoform 3) compared to isoform 1.
    Source sequence(s)
    AA462640, AC140329, AK150105, BY204086, CD775714
    Consensus CDS
    CCDS27220.1
    UniProtKB/TrEMBL
    E9Q2A6, Q3UDE9
    Related
    ENSMUSP00000086661.3, ENSMUST00000089250.9
    Conserved Domains (6) summary
    cd05056
    Location:418687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00219
    Location:425679
    TyrKc; Tyrosine kinase, catalytic domain
    smart00295
    Location:41254
    B41; Band 4.1 homologues
    cd13190
    Location:261368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    cd14473
    Location:150254
    FERM_B-lobe; FERM domain B-lobe
    pfam03623
    Location:830959
    Focal_AT; Focal adhesion targeting region

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    66390706..66518549 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017315926.2XP_017171415.1  protein-tyrosine kinase 2-beta isoform X1

    Conserved Domains (5) summary
    cd05056
    Location:418687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:41254
    B41; Band 4.1 homologues
    cd13190
    Location:261368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:8831012
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:39137
    FERM_N_2; FERM N-terminal domain
  2. XM_017315930.3XP_017171419.1  protein-tyrosine kinase 2-beta isoform X2

    Conserved Domains (5) summary
    cd05056
    Location:418687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:41254
    B41; Band 4.1 homologues
    cd13190
    Location:261368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:841970
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:39137
    FERM_N_2; FERM N-terminal domain
  3. XM_036158524.1XP_036014417.1  protein-tyrosine kinase 2-beta isoform X1

    Conserved Domains (5) summary
    cd05056
    Location:418687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:41254
    B41; Band 4.1 homologues
    cd13190
    Location:261368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:8831012
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:39137
    FERM_N_2; FERM N-terminal domain
  4. XM_036158525.1XP_036014418.1  protein-tyrosine kinase 2-beta isoform X1

    Conserved Domains (5) summary
    cd05056
    Location:418687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:41254
    B41; Band 4.1 homologues
    cd13190
    Location:261368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:8831012
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:39137
    FERM_N_2; FERM N-terminal domain
  5. XM_017315929.2XP_017171418.1  protein-tyrosine kinase 2-beta isoform X1

    Conserved Domains (5) summary
    cd05056
    Location:418687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:41254
    B41; Band 4.1 homologues
    cd13190
    Location:261368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:8831012
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:39137
    FERM_N_2; FERM N-terminal domain
  6. XM_017315927.2XP_017171416.1  protein-tyrosine kinase 2-beta isoform X1

    Conserved Domains (5) summary
    cd05056
    Location:418687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:41254
    B41; Band 4.1 homologues
    cd13190
    Location:261368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:8831012
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:39137
    FERM_N_2; FERM N-terminal domain
  7. XM_036158526.1XP_036014419.1  protein-tyrosine kinase 2-beta isoform X1

    Conserved Domains (5) summary
    cd05056
    Location:418687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:41254
    B41; Band 4.1 homologues
    cd13190
    Location:261368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:8831012
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:39137
    FERM_N_2; FERM N-terminal domain
  8. XM_017315928.2XP_017171417.1  protein-tyrosine kinase 2-beta isoform X1

    Conserved Domains (5) summary
    cd05056
    Location:418687
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:41254
    B41; Band 4.1 homologues
    cd13190
    Location:261368
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:8831012
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:39137
    FERM_N_2; FERM N-terminal domain
Support Center