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Pvalb parvalbumin [ Mus musculus (house mouse) ]

Gene ID: 19293, updated on 8-Jun-2021

Summary

Official Symbol
Pvalbprovided by MGI
Official Full Name
parvalbuminprovided by MGI
Primary source
MGI:MGI:97821
See related
Ensembl:ENSMUSG00000005716
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
PV; Pva; Parv
Expression
Biased expression in cerebellum adult (RPKM 192.6), mammary gland adult (RPKM 147.4) and 2 other tissues See more
Orthologs
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Genomic context

See Pvalb in Genome Data Viewer
Location:
15 E1; 15 36.93 cM
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (78075312..78090600, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (78191112..78206400, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (78021547..78036781, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene calcium channel, voltage-dependent, gamma subunit 2 Neighboring gene RIKEN cDNA A730060N03 gene Neighboring gene intraflagellar transport 27 Neighboring gene neutrophil cytosolic factor 4 Neighboring gene microRNA 7676-1 Neighboring gene colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables calcium ion binding ISO
Inferred from Sequence Orthology
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in axon IDA
Inferred from Direct Assay
more info
PubMed 
located_in cuticular plate ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol TAS
Traceable Author Statement
more info
 
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 
located_in stereocilium ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001330686.1NP_001317615.1  parvalbumin alpha

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AI645659, AK131986, DV051867
    Consensus CDS
    CCDS27609.1
    UniProtKB/Swiss-Prot
    P32848
    UniProtKB/TrEMBL
    Q545M7
    Related
    ENSMUSP00000005860.10, ENSMUST00000005860.16
    Conserved Domains (1) summary
    cd16254
    Location:9109
    EFh_parvalbumin_alpha; EF-hand, calcium binding motif, found in alpha-parvalbumin
  2. NM_013645.4NP_038673.2  parvalbumin alpha

    See identical proteins and their annotated locations for NP_038673.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AA467036, AI645659, AL589692, CK622340, DV051867
    Consensus CDS
    CCDS27609.1
    UniProtKB/Swiss-Prot
    P32848
    UniProtKB/TrEMBL
    Q545M7
    Related
    ENSMUSP00000112598.2, ENSMUST00000120592.2
    Conserved Domains (1) summary
    cd16254
    Location:9109
    EFh_parvalbumin_alpha; EF-hand, calcium binding motif, found in alpha-parvalbumin

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    78075312..78090600 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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