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Rad51ap1 RAD51 associated protein 1 [ Mus musculus (house mouse) ]

Gene ID: 19362, updated on 23-Jun-2021

Summary

Official Symbol
Rad51ap1provided by MGI
Official Full Name
RAD51 associated protein 1provided by MGI
Primary source
MGI:MGI:1098224
See related
Ensembl:ENSMUSG00000030346
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
RAB; RAB22; 2510006L10Rik
Expression
Biased expression in liver E14 (RPKM 17.5), liver E14.5 (RPKM 14.3) and 10 other tissues See more
Orthologs
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Genomic context

See Rad51ap1 in Genome Data Viewer
Location:
6 F3; 6 61.92 cM
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (126900378..126916664, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (126923415..126939621, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (126873437..126889573, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene A kinase (PRKA) anchor protein 3 Neighboring gene dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 Neighboring gene metaxin 1 pseudogene Neighboring gene DNA segment, Chr 6, Wayne State University 163, expressed Neighboring gene predicted gene 43124

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables D-loop DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables DNA secondary structure binding ISO
Inferred from Sequence Orthology
more info
 
enables RNA binding ISO
Inferred from Sequence Orthology
more info
 
enables double-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables single-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables single-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in chromatin ISO
Inferred from Sequence Orthology
more info
 
located_in chromosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in chromosome, telomeric region IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
RAD51-associated protein 1
Names
RAD51-interacting protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001347455.1NP_001334384.1  RAD51-associated protein 1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1
    Source sequence(s)
    AK077829, AK079525, AW457762, BB620338
    Consensus CDS
    CCDS85161.1
    UniProtKB/Swiss-Prot
    Q8C551
    UniProtKB/TrEMBL
    A0A0R4J1H1
    Related
    ENSMUSP00000107839.2, ENSMUST00000112220.8
  2. NM_009013.4NP_033039.2  RAD51-associated protein 1 isoform 1

    See identical proteins and their annotated locations for NP_033039.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AK077829, AK079525, AW457762, BB620338
    Consensus CDS
    CCDS39644.1
    UniProtKB/Swiss-Prot
    Q8C551
    UniProtKB/TrEMBL
    A0A0R4J1G4
    Related
    ENSMUSP00000107841.2, ENSMUST00000112221.8
    Conserved Domains (2) summary
    pfam10486
    Location:126268
    PI3K_1B_p101; Phosphoinositide 3-kinase gamma adapter protein p101 subunit
    pfam15696
    Location:293331
    RAD51_interact; RAD51 interacting motif

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    126900378..126916664 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030255239.1XP_030111099.1  RAD51-associated protein 1 isoform X1

    Conserved Domains (2) summary
    pfam10500
    Location:46148
    SR-25; Nuclear RNA-splicing-associated protein
    pfam15696
    Location:193231
    RAD51_interact; RAD51 interacting motif
  2. XM_030255240.1XP_030111100.1  RAD51-associated protein 1 isoform X1

    Conserved Domains (2) summary
    pfam10500
    Location:46148
    SR-25; Nuclear RNA-splicing-associated protein
    pfam15696
    Location:193231
    RAD51_interact; RAD51 interacting motif

RNA

  1. XR_004942924.1 RNA Sequence

  2. XR_377433.4 RNA Sequence

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