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Cyp6a16 Cytochrome P450 6a16 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 19836250, updated on 29-Dec-2023

Summary

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Official Symbol
Cyp6a16provided by FlyBase
Official Full Name
Cytochrome P450 6a16provided by FlyBase
Primary source
FLYBASE:FBgn0031726
Locus tag
Dmel_CG7249
See related
AllianceGenome:FB:FBgn0031726
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
6a16; CG7249; CR7249; Cyp6a16p; Cyp6a16Psi; Dmel\CG7249
Summary
Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. Is expressed in amnioserosa; embryonic Malpighian tubule; and yolk nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
25F1-25F1; 2-17 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5620615..5623762, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5620615..5623762, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Dpr-interacting protein eta Neighboring gene long non-coding RNA:CR44795 Neighboring gene long non-coding RNA:CR44796 Neighboring gene Dpr-interacting protein theta Neighboring gene long non-coding RNA:CR44822 Neighboring gene mir-959 stem loop

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Integrative genome-wide analysis of dopaminergic neuron-specific PARIS expression in Drosophila dissects recognition of multiple PPAR-γ associated gene regulation. Yazar V, et al. Sci Rep, 2021 Nov 2. PMID 34728675, Free PMC Article
  2. The molecular evolution of cytochrome P450 genes within and between drosophila species. Good RT, et al. Genome Biol Evol, 2014 Apr 20. PMID 24751979, Free PMC Article
  3. The cytochrome P450 gene superfamily in Drosophila melanogaster: annotation, intron-exon organization and phylogeny. Tijet N, et al. Gene, 2001 Jan 10. PMID 11179683
  4. Genomic and transcriptomic analyses in Drosophila suggest that the ecdysteroid kinase-like (EcKL) gene family encodes the 'detoxification-by-phosphorylation' enzymes of insects. Scanlan JL, et al. Insect Biochem Mol Biol, 2020 Aug. PMID 32540344
  5. Whole-genome expression analysis in the third instar larval midgut of Drosophila melanogaster. Harrop TW, et al. G3 (Bethesda), 2014 Sep 5. PMID 25193493, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
NOT enables monooxygenase activity IKR
Inferred from Key Residues
more info
 PubMed 
NOT enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IKR
Inferred from Key Residues
more info
 PubMed 

General protein information

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Preferred Names
cytochrome P450 6a16
Names
CG7249-PB
CG7249-PC
Cyp6a16-PB
Cyp6a16-PC
Cyp6a16Psi
NP_001285631.1
  • complex mutation, may be evolving pseudogene
NP_001285632.1
  • complex mutation, may be evolving pseudogene

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    5620615..5623762 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298702.1 → NP_001285631.1  cytochrome P450 6a16, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285631.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    X2J9F6
    Conserved Domains (1) summary
    pfam00067
    Location:32 → 492
    p450; Cytochrome P450

  2. NM_001298703.1 → NP_001285632.1  cytochrome P450 6a16, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285632.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    X2J9F6
    Conserved Domains (1) summary
    pfam00067
    Location:32 → 492
    p450; Cytochrome P450
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
X2J9F6 X2J9F6

Gene LinkOut

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Molecular Biology Databases