U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Sbp spermine binding protein [ Mus musculus (house mouse) ]

Gene ID: 20234, updated on 8-Feb-2024

Summary

Go to the top of the page Help
Official Symbol
Sbpprovided by MGI
Official Full Name
spermine binding proteinprovided by MGI
Primary source
MGI:MGI:106021
See related
Ensembl:ENSMUSG00000024128 AllianceGenome:MGI:106021
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
p25
Summary
Predicted to enable carbohydrate binding activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in prostate gland dorsolateral lobe and ventral prostate gland. Orthologous to human ZG16B (zymogen granule protein 16B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
17 A3.3; 17 12.15 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (24141525..24164577)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (23922551..23945603)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_42067 Neighboring gene 60S ribosomal protein L7a pseudogene Neighboring gene predicted gene, 41545 Neighboring gene demilune cell and parotid protein 3 Neighboring gene spermine binding protein-like Neighboring gene predicted gene, 41546 Neighboring gene serine protease 30

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Opposing roles of transient and prolonged expression of p25 in synaptic plasticity and hippocampus-dependent memory. Fischer A, et al. Neuron, 2005 Dec 8. PMID 16337919
  2. Androgen regulated expression of a spermine binding protein gene in mouse ventral prostate. Mills JS, et al. Nucleic Acids Res, 1987 Oct 12. PMID 3502715, Free PMC Article
  3. Secreted frizzled related protein 1 is a paracrine modulator of epithelial branching morphogenesis, proliferation, and secretory gene expression in the prostate. Joesting MS, et al. Dev Biol, 2008 May 1. PMID 18371946, Free PMC Article
  4. Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J. Timmermans S, et al. JCI Insight, 2018 Jul 12. PMID 29997285, Free PMC Article
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in cell migration ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in apicolateral plasma membrane ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in extracellular region ISO
Inferred from Sequence Orthology
more info
 PubMed 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
prostatic spermine-binding protein
Names
major prostatic secretory glycoprotein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001384094.1 → NP_001371023.1  prostatic spermine-binding protein precursor

    Status: VALIDATED

    Source sequence(s)
    AC110262
    UniProtKB/Swiss-Prot
    P15501
    UniProtKB/TrEMBL
    Q544L5, S4R244
    Related
    ENSMUSP00000138422.2, ENSMUST00000181985.8
    Conserved Domains (1) summary
    cd09611
    Location:22 → 150
    Jacalin_ZG16_like; Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins

  2. NM_001384097.1 → NP_001371026.1  prostatic spermine-binding protein precursor

    Status: VALIDATED

    Source sequence(s)
    AC110262
    UniProtKB/Swiss-Prot
    P15501
    UniProtKB/TrEMBL
    Q544L5, S4R244
    Conserved Domains (1) summary
    cd09611
    Location:22 → 150
    Jacalin_ZG16_like; Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins

  3. NM_001384098.1 → NP_001371027.1  prostatic spermine-binding protein precursor

    Status: VALIDATED

    Source sequence(s)
    AC110262
    UniProtKB/Swiss-Prot
    P15501
    UniProtKB/TrEMBL
    Q544L5, S4R244
    Conserved Domains (1) summary
    cd09611
    Location:22 → 150
    Jacalin_ZG16_like; Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins

  4. NM_001384100.1 → NP_001371029.1  prostatic spermine-binding protein precursor

    Status: VALIDATED

    Source sequence(s)
    AC110262
    UniProtKB/Swiss-Prot
    P15501
    UniProtKB/TrEMBL
    Q544L5, S4R244
    Related
    ENSMUSP00000024940.5, ENSMUST00000024940.11
    Conserved Domains (1) summary
    cd09611
    Location:22 → 150
    Jacalin_ZG16_like; Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins

  5. NM_011321.4 → NP_035451.1  prostatic spermine-binding protein precursor

    See identical proteins and their annotated locations for NP_035451.1

    Status: VALIDATED

    Source sequence(s)
    AC110262
    Consensus CDS
    CCDS57056.1
    UniProtKB/Swiss-Prot
    P15501
    UniProtKB/TrEMBL
    Q544L5, S4R244
    Related
    ENSMUSP00000138219.2, ENSMUST00000183252.8
    Conserved Domains (1) summary
    cd09611
    Location:22 → 150
    Jacalin_ZG16_like; Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    24141525..24164577
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P15501.1 GenPept UniProtKB/Swiss-Prot:P15501

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous