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Cavin2 caveolae associated 2 [ Mus musculus (house mouse) ]

Gene ID: 20324, updated on 5-Jan-2022

Summary

Official Symbol
Cavin2provided by MGI
Official Full Name
caveolae associated 2provided by MGI
Primary source
MGI:MGI:99513
See related
Ensembl:ENSMUSG00000045954
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Sdpr
Summary
Predicted to enable phosphatidylserine binding activity and protein kinase C binding activity. Predicted to be involved in plasma membrane tubulation. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in several cellular components, including cytosol; membrane raft; and nucleoplasm. Predicted to be active in caveola and cytoplasm. Is expressed in several structures, including genitourinary system; head mesenchyme; sensory organ; tongue; and trunk mesenchyme. Orthologous to human CAVIN2 (caveolae associated protein 2). [provided by Alliance of Genome Resources, Nov 2021]
Expression
Broad expression in lung adult (RPKM 123.4), subcutaneous fat pad adult (RPKM 70.9) and 16 other tissues See more
Orthologs
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Genomic context

See Cavin2 in Genome Data Viewer
Location:
1; 1 C1.1
Exon count:
2
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (51328285..51342119)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (51289126..51302960)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (51345970..51359804)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene 28321 Neighboring gene transmembrane protein with EGF-like and two follistatin-like domains 2 Neighboring gene RIKEN cDNA 9330175M20 gene Neighboring gene THO complex 3 pseudogene Neighboring gene nucleic acid binding protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables lipid binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphatidylserine binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein kinase C binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in caveola IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in caveola ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane raft ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
caveolae-associated protein 2
Names
cavin-2
phosphatidylserine-binding protein
serum deprivation response
serum deprivation-response protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138741.1NP_620080.1  caveolae-associated protein 2

    See identical proteins and their annotated locations for NP_620080.1

    Status: VALIDATED

    Source sequence(s)
    BC027005
    Consensus CDS
    CCDS14940.1
    UniProtKB/Swiss-Prot
    Q63918
    Related
    ENSMUSP00000055694.7, ENSMUST00000051572.8
    Conserved Domains (1) summary
    pfam15237
    Location:53294
    PTRF_SDPR; PTRF/SDPR family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    51328285..51342119
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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