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Sec61g SEC61, gamma subunit [ Mus musculus (house mouse) ]

Gene ID: 20335, updated on 23-Jun-2021

Summary

Official Symbol
Sec61gprovided by MGI
Official Full Name
SEC61, gamma subunitprovided by MGI
Primary source
MGI:MGI:1202066
See related
Ensembl:ENSMUSG00000078974
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Expression
Broad expression in liver E14 (RPKM 73.5), placenta adult (RPKM 63.1) and 24 other tissues See more
Orthologs
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Genomic context

See Sec61g in Genome Data Viewer
Location:
11; 11 A2
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (16451638..16458484, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (16501638..16508484, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (16401641..16408487, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene V-set and transmembrane domain containing 2A Neighboring gene predicted gene 12012 Neighboring gene thymoma viral proto-oncogene 2, pseudogene Neighboring gene VISTA enhancer mm1103

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein-transporting ATPase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in posttranslational protein targeting to membrane, translocation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein targeting IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of Ssh1 translocon complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane ISO
Inferred from Sequence Orthology
more info
PubMed 

General protein information

Preferred Names
protein transport protein Sec61 subunit gamma

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109971.1NP_001103441.1  protein transport protein Sec61 subunit gamma isoform 2

    See identical proteins and their annotated locations for NP_001103441.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) includes an alternate segment in exon 1, compared to variant 1. This causes translation initiation at a downstream AUG and an isoform (2) with a shorter N-terminus compared to isoform 1.
    Source sequence(s)
    AK012393, AK012644, BY468217, CO808059
    Consensus CDS
    CCDS48755.1
    UniProtKB/Swiss-Prot
    P60060
    UniProtKB/TrEMBL
    Q5SWJ8
    Related
    ENSMUSP00000137362.2, ENSMUST00000178855.8
    Conserved Domains (1) summary
    cl00481
    Location:1268
    SecE; SecE/Sec61-gamma subunits of protein translocation complex
  2. NM_001109972.1NP_001103442.1  protein transport protein Sec61 subunit gamma isoform 2

    See identical proteins and their annotated locations for NP_001103442.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) includes an alternate segment in exon 1, compared to variant 1. This causes translation initiation at a downstream AUG and an isoform (2) with a shorter N-terminus compared to isoform 1.
    Source sequence(s)
    AK012644, AV456975, CO808059
    Consensus CDS
    CCDS48755.1
    UniProtKB/Swiss-Prot
    P60060
    UniProtKB/TrEMBL
    Q5SWJ8
    Related
    ENSMUSP00000105270.2, ENSMUST00000109642.8
    Conserved Domains (1) summary
    cl00481
    Location:1268
    SecE; SecE/Sec61-gamma subunits of protein translocation complex
  3. NM_011343.3NP_035473.2  protein transport protein Sec61 subunit gamma isoform 1

    See identical proteins and their annotated locations for NP_035473.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AK012644, CO808059
    Consensus CDS
    CCDS48756.1
    UniProtKB/Swiss-Prot
    P60060
    UniProtKB/TrEMBL
    G3UWH0
    Related
    ENSMUSP00000132348.2, ENSMUST00000166950.8
    Conserved Domains (1) summary
    cl00481
    Location:44100
    SecE; SecE/Sec61-gamma subunits of protein translocation complex

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    16451638..16458484 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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