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Slc5a1 solute carrier family 5 (sodium/glucose cotransporter), member 1 [ Mus musculus (house mouse) ]

Gene ID: 20537, updated on 23-Jun-2021

Summary

Official Symbol
Slc5a1provided by MGI
Official Full Name
solute carrier family 5 (sodium/glucose cotransporter), member 1provided by MGI
Primary source
MGI:MGI:107678
See related
Ensembl:ENSMUSG00000011034
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Sgl; Sglt1
Expression
Biased expression in duodenum adult (RPKM 227.7), small intestine adult (RPKM 214.0) and 3 other tissues See more
Orthologs
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Genomic context

See Slc5a1 in Genome Data Viewer
Location:
5; 5 B1
Exon count:
15
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (33261563..33320043)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (33104219..33162699)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (33446868..33505348)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L35A, pseudogene 5 Neighboring gene small nucleolar RNA SNORA48 Neighboring gene uncharacterized LOC118568785 Neighboring gene spondin 2, extracellular matrix protein

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables D-glucose transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
enables alpha-glucoside transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
enables glucose transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables glucose transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
enables glucose:sodium symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables glucose:sodium symporter activity ISO
Inferred from Sequence Orthology
more info
 
enables symporter activity IEA
Inferred from Electronic Annotation
more info
 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables water transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in apical plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in apical plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in brush border IDA
Inferred from Direct Assay
more info
PubMed 
located_in brush border membrane ISO
Inferred from Sequence Orthology
more info
 
located_in cell-cell junction ISO
Inferred from Sequence Orthology
more info
 
located_in early endosome ISO
Inferred from Sequence Orthology
more info
 
is_active_in integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in intracellular organelle ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
sodium/glucose cotransporter 1
Names
Na(+)/glucose cotransporter 1
high affinity sodium-glucose cotransporter
solute carrier family 5, member 1
solute carrier family 5, member alpha 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019810.4NP_062784.3  sodium/glucose cotransporter 1

    See identical proteins and their annotated locations for NP_062784.3

    Status: VALIDATED

    Source sequence(s)
    AC122203, AK033512, AK085602, BE688659
    Consensus CDS
    CCDS19199.1
    UniProtKB/Swiss-Prot
    Q8C3K6
    UniProtKB/TrEMBL
    Q8CCA7, Q9QXI6
    Related
    ENSMUSP00000011178.3, ENSMUST00000011178.5
    Conserved Domains (1) summary
    cl00456
    Location:27665
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    33261563..33320043
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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