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Smr2 submaxillary gland androgen regulated protein 2 [ Mus musculus (house mouse) ]

Gene ID: 20600, updated on 23-Jun-2021

Summary

Official Symbol
Smr2provided by MGI
Official Full Name
submaxillary gland androgen regulated protein 2provided by MGI
Primary source
MGI:MGI:102762
See related
Ensembl:ENSMUSG00000029281
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MSG; MSG2; Vcs2
Expression
Low expression observed in reference dataset See more
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Genomic context

See Smr2 in Genome Data Viewer
Location:
5; 5 E1
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (88234415..88256912)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (88086556..88109053)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (88515581..88538078)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene submaxillary gland androgen regulated protein 3A Neighboring gene heat shock protein 5 pseudogene Neighboring gene predicted gene 42622 Neighboring gene heat shock protein 8 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Clone Names

  • MGC130573

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables endopeptidase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables endopeptidase inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
enables peptidase inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in cellular response to lipopolysaccharide ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of peptidase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of sensory perception of pain IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of sensory perception of pain ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within response to toxic substance IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extracellular region ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
submaxillary gland androgen regulated protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001252679.1NP_001239608.1  submaxillary gland androgen regulated protein 2 isoform 2 precursor

    See identical proteins and their annotated locations for NP_001239608.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains two alternate internal exons and initiates translation at an alternate start codon, compared to variant 1. Variants 2, 3 and 4 encode the same isoform (2) which has a distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AC154123, AC163331
    Consensus CDS
    CCDS80321.1
    UniProtKB/Swiss-Prot
    O35979
    Related
    ENSMUSP00000143443.2, ENSMUST00000196070.2
    Conserved Domains (1) summary
    pfam15621
    Location:1111
    PROL5-SMR; Proline-rich submaxillary gland androgen-regulated family
  2. NM_001252680.1NP_001239609.1  submaxillary gland androgen regulated protein 2 isoform 2 precursor

    See identical proteins and their annotated locations for NP_001239609.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) contains an alternate internal exon and initiates translation at an alternate start codon, compared to variant 1. Variants 2, 3 and 4 encode the same isoform (2) which has a distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AC154123, AC163331
    Consensus CDS
    CCDS80321.1
    UniProtKB/Swiss-Prot
    O35979
    Conserved Domains (1) summary
    pfam15621
    Location:1111
    PROL5-SMR; Proline-rich submaxillary gland androgen-regulated family
  3. NM_001252681.1NP_001239610.1  submaxillary gland androgen regulated protein 2 isoform 2 precursor

    See identical proteins and their annotated locations for NP_001239610.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an internal exon, contains an alternate internal exon and initiates translation at an alternate start codon, compared to variant 1. Variants 2, 3 and 4 encode the same isoform (2) which has a distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AC154123, AC163331
    Consensus CDS
    CCDS80321.1
    UniProtKB/Swiss-Prot
    O35979
    Related
    ENSMUSP00000142688.2, ENSMUST00000196477.5
    Conserved Domains (1) summary
    pfam15621
    Location:1111
    PROL5-SMR; Proline-rich submaxillary gland androgen-regulated family
  4. NM_021289.2NP_067264.2  submaxillary gland androgen regulated protein 2 isoform 1 precursor

    See identical proteins and their annotated locations for NP_067264.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform (1).
    Source sequence(s)
    AC154123, AC163331
    Consensus CDS
    CCDS39137.1
    UniProtKB/Swiss-Prot
    O35985
    Related
    ENSMUSP00000084271.4, ENSMUST00000087043.8
    Conserved Domains (1) summary
    pfam15621
    Location:1111
    PROL5-SMR; Proline-rich submaxillary gland androgen-regulated family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    88234415..88256912
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030254268.1XP_030110128.1  submaxillary gland androgen regulated protein 2 isoform X1

    Related
    ENSMUSP00000142444.2, ENSMUST00000199635.5
    Conserved Domains (1) summary
    pfam15621
    Location:1116
    PROL5-SMR; Proline-rich submaxillary gland androgen-regulated family
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