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Sprr2k small proline-rich protein 2K [ Mus musculus (house mouse) ]

Gene ID: 20765, updated on 8-Feb-2024

Summary

Official Symbol
Sprr2kprovided by MGI
Official Full Name
small proline-rich protein 2Kprovided by MGI
Primary source
MGI:MGI:1330344
See related
Ensembl:ENSMUSG00000054215 AllianceGenome:MGI:1330344
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to act upstream of or within keratinization. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

Location:
3 F1; 3 40.14 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (92339889..92341234)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (92432582..92433927)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene small proline-rich protein 2J, pseudogene Neighboring gene adhesion regulating molecule 1B Neighboring gene small proline-rich protein 1B Neighboring gene small proline-rich protein 3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in epidermis development NAS
Non-traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within keratinization IEA
Inferred from Electronic Annotation
more info
 
involved_in keratinocyte differentiation NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in cornified envelope NAS
Non-traceable Author Statement
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
small proline-rich protein 2K

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011477.3NP_035607.2  small proline-rich protein 2K

    See identical proteins and their annotated locations for NP_035607.2

    Status: VALIDATED

    Source sequence(s)
    AC127036, AY158995, BC116866
    Consensus CDS
    CCDS38512.1
    UniProtKB/Swiss-Prot
    O70562
    UniProtKB/TrEMBL
    G5E8D1
    Related
    ENSMUSP00000063287.3, ENSMUST00000067102.3
    Conserved Domains (1) summary
    pfam14820
    Location:265
    SPRR2; Small proline-rich 2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    92339889..92341234
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)