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Ttc28 tetratricopeptide repeat domain 28 [ Mus musculus (house mouse) ]

Gene ID: 209683, updated on 23-Jun-2021

Summary

Official Symbol
Ttc28provided by MGI
Official Full Name
tetratricopeptide repeat domain 28provided by MGI
Primary source
MGI:MGI:2140873
See related
Ensembl:ENSMUSG00000033209
Gene type
protein coding
RefSeq status
INFERRED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
TPR; TPRBK; AI428795; AI851761; BC002262; 6030435N04; 2310015L07Rik
Expression
Broad expression in whole brain E14.5 (RPKM 8.8), CNS E14 (RPKM 8.2) and 24 other tissues See more
Orthologs
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Genomic context

See Ttc28 in Genome Data Viewer
Location:
5; 5 F
Exon count:
25
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (111027652..111437646)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (110879785..111289780)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (111308822..111718799)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene ES cell cis-regulatory motif 10b Neighboring gene HscB iron-sulfur cluster co-chaperone Neighboring gene checkpoint kinase 2 Neighboring gene microRNA 701 Neighboring gene predicted gene, 35628 Neighboring gene phosphatidylinositol transfer protein, beta Neighboring gene predicted gene, 36027 Neighboring gene meningioma 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC7623

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables kinase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within regulation of mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
PubMed 
involved_in regulation of mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in centrosome ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in midbody ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in mitotic spindle ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in mitotic spindle midzone ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in mitotic spindle pole ISO
Inferred from Sequence Orthology
more info
PubMed 

General protein information

Preferred Names
tetratricopeptide repeat protein 28
Names
TPR repeat protein 28
NP_001254551.1
XP_006534908.1
XP_006534909.1
XP_030110193.1
XP_030110194.1
XP_030110195.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001267622.1NP_001254551.1  tetratricopeptide repeat protein 28

    See identical proteins and their annotated locations for NP_001254551.1

    Status: INFERRED

    Source sequence(s)
    AC121934, AC122226, AC124425, AC155173, AW492543, BC046779
    Consensus CDS
    CCDS59682.1
    UniProtKB/Swiss-Prot
    Q80XJ3
    Related
    ENSMUSP00000137609.2, ENSMUST00000156290.9
    Conserved Domains (7) summary
    smart00028
    Location:388420
    TPR; Tetratricopeptide repeats
    COG0457
    Location:688989
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:85115
    TPR; TPR repeat [structural motif]
    pfam12770
    Location:13841707
    CHAT; CHAT domain
    pfam13176
    Location:953988
    TPR_7; Tetratricopeptide repeat
    pfam13414
    Location:88151
    TPR_11; TPR repeat
    pfam13424
    Location:309380
    TPR_12; Tetratricopeptide repeat

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    111027652..111437646
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006534845.5XP_006534908.1  tetratricopeptide repeat protein 28 isoform X1

    Conserved Domains (5) summary
    PHA03377
    Location:19502334
    PHA03377; EBNA-3C; Provisional
    TIGR02917
    Location:27838
    PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
    sd00006
    Location:495523
    TPR; TPR repeat [structural motif]
    pfam12770
    Location:12911614
    CHAT; CHAT domain
    pfam17874
    Location:7331053
    TPR_MalT; MalT-like TPR region
  2. XM_030254333.2XP_030110193.1  tetratricopeptide repeat protein 28 isoform X3

    Conserved Domains (5) summary
    PHA03377
    Location:18842268
    PHA03377; EBNA-3C; Provisional
    COG0457
    Location:278552
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:429457
    TPR; TPR repeat [structural motif]
    pfam13424
    Location:834904
    TPR_12; Tetratricopeptide repeat
    pfam12770
    Location:12251548
    CHAT; CHAT domain
  3. XM_030254334.2XP_030110194.1  tetratricopeptide repeat protein 28 isoform X3

    Conserved Domains (5) summary
    PHA03377
    Location:18842268
    PHA03377; EBNA-3C; Provisional
    COG0457
    Location:278552
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:429457
    TPR; TPR repeat [structural motif]
    pfam13424
    Location:834904
    TPR_12; Tetratricopeptide repeat
    pfam12770
    Location:12251548
    CHAT; CHAT domain
  4. XM_030254335.2XP_030110195.1  tetratricopeptide repeat protein 28 isoform X3

    Conserved Domains (5) summary
    PHA03377
    Location:18842268
    PHA03377; EBNA-3C; Provisional
    COG0457
    Location:278552
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:429457
    TPR; TPR repeat [structural motif]
    pfam13424
    Location:834904
    TPR_12; Tetratricopeptide repeat
    pfam12770
    Location:12251548
    CHAT; CHAT domain
  5. XM_006534846.5XP_006534909.1  tetratricopeptide repeat protein 28 isoform X2

    Conserved Domains (5) summary
    PHA03377
    Location:19312315
    PHA03377; EBNA-3C; Provisional
    TIGR02917
    Location:9819
    PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
    sd00006
    Location:476504
    TPR; TPR repeat [structural motif]
    pfam12770
    Location:12721595
    CHAT; CHAT domain
    pfam17874
    Location:7141034
    TPR_MalT; MalT-like TPR region

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_024477.3: Suppressed sequence

    Description
    NM_024477.3: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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