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Adcy2 adenylate cyclase 2 [ Mus musculus (house mouse) ]

Gene ID: 210044, updated on 23-Jun-2021

Summary

Official Symbol
Adcy2provided by MGI
Official Full Name
adenylate cyclase 2provided by MGI
Primary source
MGI:MGI:99676
See related
Ensembl:ENSMUSG00000021536
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA1060
Expression
Biased expression in frontal lobe adult (RPKM 27.4), cortex adult (RPKM 24.4) and 8 other tissues See more
Orthologs
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Genomic context

See Adcy2 in Genome Data Viewer
Location:
13 B3; 13 35.55 cM
Exon count:
25
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (68768162..69147719, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (68620043..68999600, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (68758920..69138419, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700001L19 gene Neighboring gene FAST kinase domains 3 Neighboring gene 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Neighboring gene predicted gene, 34903 Neighboring gene farnesyl diphosphate synthetase pseudogene Neighboring gene predicted gene, 35161 Neighboring gene predicted gene, 35049 Neighboring gene predicted gene, 26844

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • MGC47193

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables G-protein beta/gamma-subunit complex binding ISO
Inferred from Sequence Orthology
more info
 
enables adenylate cyclase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables adenylate cyclase activity ISO
Inferred from Sequence Orthology
more info
 
enables adenylate cyclase activity TAS
Traceable Author Statement
more info
PubMed 
enables adenylate cyclase binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables adenylate cyclase binding ISO
Inferred from Sequence Orthology
more info
 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables magnesium ion binding ISO
Inferred from Sequence Orthology
more info
 
enables manganese ion binding ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphorus-oxygen lyase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in dendrite IDA
Inferred from Direct Assay
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane raft ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
PubMed 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
adenylate cyclase type 2
Names
ATP pyrophosphate-lyase 2
adenylate cyclase type II
adenylyl cyclase 2
NP_705762.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153534.2NP_705762.2  adenylate cyclase type 2

    See identical proteins and their annotated locations for NP_705762.2

    Status: VALIDATED

    Source sequence(s)
    AI322582, AK132312, BY623048
    Consensus CDS
    CCDS36721.1
    UniProtKB/TrEMBL
    Q3V1Q3
    Related
    ENSMUSP00000022013.8, ENSMUST00000022013.8
    Conserved Domains (4) summary
    smart00044
    Location:240443
    CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
    pfam00211
    Location:8821081
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam06327
    Location:499603
    DUF1053; Domain of Unknown Function (DUF1053)
    pfam16214
    Location:37264
    AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    68768162..69147719 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_001780768.2 RNA Sequence

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