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Mfsd4a major facilitator superfamily domain containing 4A [ Mus musculus (house mouse) ]

Gene ID: 213006, updated on 23-Jun-2021

Summary

Official Symbol
Mfsd4aprovided by MGI
Official Full Name
major facilitator superfamily domain containing 4Aprovided by MGI
Primary source
MGI:MGI:2442786
See related
Ensembl:ENSMUSG00000059149
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mfsd; Mfsd4; AI850289; A230072B04; A930031D07Rik
Expression
Broad expression in colon adult (RPKM 40.5), adrenal adult (RPKM 15.7) and 17 other tissues See more
Orthologs
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Genomic context

See Mfsd4a in Genome Data Viewer
Location:
1; 1 E4
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (131947543..131997400, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (132022806..132069658, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (133923198..133964639, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene nuclear casein kinase and cyclin-dependent kinase substrate 1 Neighboring gene solute carrier family 45, member 3 Neighboring gene ELK4, member of ETS oncogene family Neighboring gene RIKEN cDNA 4833413N01 gene Neighboring gene predicted gene, 37120

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables glucose transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
major facilitator superfamily domain-containing protein 4A
Names
major facilitator superfamily domain containing 4
major facilitator superfamily domain-containing protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001114662.1NP_001108134.1  major facilitator superfamily domain-containing protein 4A isoform b

    See identical proteins and their annotated locations for NP_001108134.1

    Status: VALIDATED

    Source sequence(s)
    AC107837, AI642828, AK048692, AK085484, AK162495
    Consensus CDS
    CCDS48357.1
    UniProtKB/Swiss-Prot
    Q6PDC8
    Related
    ENSMUSP00000125558.2, ENSMUST00000159038.8
    Conserved Domains (2) summary
    cd06174
    Location:298480
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam07690
    Location:22442
    MFS_1; Major Facilitator Superfamily
  2. NM_172510.4NP_766098.2  major facilitator superfamily domain-containing protein 4A isoform a

    See identical proteins and their annotated locations for NP_766098.2

    Status: VALIDATED

    Source sequence(s)
    AK048692, AK162495
    Consensus CDS
    CCDS15280.2
    UniProtKB/Swiss-Prot
    Q6PDC8
    Related
    ENSMUSP00000107989.3, ENSMUST00000112370.9
    Conserved Domains (1) summary
    cd17453
    Location:18479
    MFS_MFSD4A; Major facilitator superfamily domain-containing protein 4A

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    131947543..131997400 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006529345.5XP_006529408.1  major facilitator superfamily domain-containing protein 4A isoform X2

    See identical proteins and their annotated locations for XP_006529408.1

    UniProtKB/Swiss-Prot
    Q6PDC8
    Conserved Domains (1) summary
    cl28910
    Location:1257
    MFS; Major Facilitator Superfamily
  2. XM_030252744.2XP_030108604.1  major facilitator superfamily domain-containing protein 4A isoform X1

    Related
    ENSMUSP00000116282.3, ENSMUST00000144548.9
    Conserved Domains (1) summary
    cd17453
    Location:18479
    MFS_MFSD4A; Major facilitator superfamily domain-containing protein 4A
  3. XM_017319650.3XP_017175139.1  major facilitator superfamily domain-containing protein 4A isoform X2

    UniProtKB/Swiss-Prot
    Q6PDC8
    Conserved Domains (1) summary
    cl28910
    Location:1257
    MFS; Major Facilitator Superfamily
  4. XM_006529344.5XP_006529407.1  major facilitator superfamily domain-containing protein 4A isoform X1

    See identical proteins and their annotated locations for XP_006529407.1

    UniProtKB/Swiss-Prot
    Q6PDC8
    Related
    ENSMUSP00000116706.2, ENSMUST00000126927.8
    Conserved Domains (1) summary
    cd17453
    Location:18479
    MFS_MFSD4A; Major facilitator superfamily domain-containing protein 4A
  5. XM_030252750.2XP_030108610.1  major facilitator superfamily domain-containing protein 4A isoform X3

    Conserved Domains (1) summary
    cl28910
    Location:1257
    MFS; Major Facilitator Superfamily

RNA

  1. XR_001783717.3 RNA Sequence

  2. XR_001783716.3 RNA Sequence

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