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Plekhg6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 [ Mus musculus (house mouse) ]

Gene ID: 213522, updated on 23-Jun-2021

Summary

Official Symbol
Plekhg6provided by MGI
Official Full Name
pleckstrin homology domain containing, family G (with RhoGef domain) member 6provided by MGI
Primary source
MGI:MGI:2682298
See related
Ensembl:ENSMUSG00000038167
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm155; BC026778
Expression
Biased expression in duodenum adult (RPKM 20.7), small intestine adult (RPKM 19.3) and 10 other tissues See more
Orthologs
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Genomic context

See Plekhg6 in Genome Data Viewer
Location:
6; 6 F3
Exon count:
17
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (125339614..125358578, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (125362651..125381615, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (125312669..125330522, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene lymphotoxin B receptor Neighboring gene sodium channel, nonvoltage-gated 1 alpha Neighboring gene tumor necrosis factor receptor superfamily, member 1a Neighboring gene predicted gene, 52918 Neighboring gene predicted gene, 32673 Neighboring gene CD9 antigen Neighboring gene predicted gene 28809

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC30363

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in cell junction ISO
Inferred from Sequence Orthology
more info
 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in centrosome ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
pleckstrin homology domain-containing family G member 6
Names
PH domain-containing family G member 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198604.2NP_941006.2  pleckstrin homology domain-containing family G member 6

    See identical proteins and their annotated locations for NP_941006.2

    Status: VALIDATED

    Source sequence(s)
    AC140324, AK153619
    Consensus CDS
    CCDS39642.1
    UniProtKB/Swiss-Prot
    Q8R0J1
    Related
    ENSMUSP00000037004.7, ENSMUST00000042647.7
    Conserved Domains (2) summary
    cd13244
    Location:408505
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    pfam00621
    Location:165351
    RhoGEF; RhoGEF domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    125339614..125358578 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006505867.3XP_006505930.1  pleckstrin homology domain-containing family G member 6 isoform X1

    See identical proteins and their annotated locations for XP_006505930.1

    UniProtKB/Swiss-Prot
    Q8R0J1
    Conserved Domains (2) summary
    cd13244
    Location:408505
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
    pfam00621
    Location:165351
    RhoGEF; RhoGEF domain
  2. XM_017321495.2XP_017176984.1  pleckstrin homology domain-containing family G member 6 isoform X2

    Conserved Domains (2) summary
    smart00325
    Location:165319
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd13244
    Location:376473
    PH_PLEKHG5_G6; Pleckstrin homology domain-containing family G member 5 and 6 pleckstrin homology (PH) domain
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