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Tcf21 transcription factor 21 [ Mus musculus (house mouse) ]

Gene ID: 21412, updated on 6-Sep-2021

Summary

Official Symbol
Tcf21provided by MGI
Official Full Name
transcription factor 21provided by MGI
Primary source
MGI:MGI:1202715
See related
Ensembl:ENSMUSG00000045680
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Po; ca; ep; Pod; epc; epi; Pod1; Pod-1; bHLHa; bHLHa23; capsulin; epicardin
Expression
Biased expression in bladder adult (RPKM 101.3), lung adult (RPKM 85.6) and 14 other tissues See more
Orthologs
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Genomic context

See Tcf21 in Genome Data Viewer
Location:
10 A3; 10 10.33 cM
Exon count:
2
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (22693162..22696042, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (22817263..22820143, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (22537069..22539934, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene TATA box binding protein-like 1 Neighboring gene microRNA 7663 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene 10824 Neighboring gene predicted gene, 51761 Neighboring gene predicted gene, 46217

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in Sertoli cell differentiation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within animal organ morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within branching involved in ureteric bud morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in branchiomeric skeletal muscle development IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within bronchiole development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in developmental process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in diaphragm development IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in embryonic digestive tract morphogenesis ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within epithelial cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in gland development ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within glomerulus development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within kidney development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within lung alveolus development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within lung morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within lung vasculature development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in metanephric glomerular capillary formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in metanephric mesenchymal cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within morphogenesis of a branching structure IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of androgen receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of histone deacetylation IC
Inferred by Curator
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within reproductive structure development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within respiratory system development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in roof of mouth development IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within sex determination IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within sex differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in spleen development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within ureteric bud development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within vasculature development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IC
Inferred by Curator
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
transcription factor 21
Names
podocyte-expressed 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011545.2NP_035675.1  transcription factor 21

    See identical proteins and their annotated locations for NP_035675.1

    Status: VALIDATED

    Source sequence(s)
    AF035717, AK011575
    Consensus CDS
    CCDS23732.1
    UniProtKB/Swiss-Prot
    O35437
    Related
    ENSMUSP00000053178.8, ENSMUST00000049930.9
    Conserved Domains (1) summary
    pfam00010
    Location:80132
    HLH; Helix-loop-helix DNA-binding domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    22693162..22696042 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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