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Tmem51 transmembrane protein 51 [ Mus musculus (house mouse) ]

Gene ID: 214359, updated on 5-Mar-2024

Summary

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Official Symbol
Tmem51provided by MGI
Official Full Name
transmembrane protein 51provided by MGI
Primary source
MGI:MGI:2384874
See related
Ensembl:ENSMUSG00000040616 AllianceGenome:MGI:2384874
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and immune system. Orthologous to human TMEM51 (transmembrane protein 51). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in genital fat pad adult (RPKM 26.9), stomach adult (RPKM 26.2) and 24 other tissues See more
Orthologs
human all
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Genomic context

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Location:
4 D3; 4 75.17 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (141758301..141811985, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (142030990..142084928, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930455G09 gene Neighboring gene forkhead-associated phosphopeptide binding domain 1 Neighboring gene STARR-positive B cell enhancer ABC_E10274 Neighboring gene forkhead-associated phosphopeptide binding domain 1, opposite strand 1 Neighboring gene STARR-seq mESC enhancer starr_11942 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:141636026-141636227 Neighboring gene Tmem51 opposite strand 1 Neighboring gene STARR-seq mESC enhancer starr_11946 Neighboring gene STARR-seq mESC enhancer starr_11949 Neighboring gene STARR-seq mESC enhancer starr_11950 Neighboring gene predicted gene, 35581 Neighboring gene kazrin, periplakin interacting protein Neighboring gene predicted gene, 35531

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs. Pan J, et al. Am J Reprod Immunol, 2015 Sep. PMID 26073538
  2. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
  3. The Vertebrate Genome Annotation browser 10 years on. Harrow JL, et al. Nucleic Acids Res, 2014 Jan. PMID 24316575, Free PMC Article
  4. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
  5. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • FLJ10199

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transmembrane protein 51

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001419368.1 → NP_001406297.1  transmembrane protein 51

    Status: VALIDATED

    Source sequence(s)
    AL663037
    UniProtKB/Swiss-Prot
    Q3TPZ3, Q99LG1

  2. NM_001419370.1 → NP_001406299.1  transmembrane protein 51

    Status: VALIDATED

    Source sequence(s)
    AL663037
    UniProtKB/Swiss-Prot
    Q3TPZ3, Q99LG1

  3. NM_001419371.1 → NP_001406300.1  transmembrane protein 51

    Status: VALIDATED

    Source sequence(s)
    AL663037
    UniProtKB/Swiss-Prot
    Q3TPZ3, Q99LG1

  4. NM_001419372.1 → NP_001406301.1  transmembrane protein 51

    Status: VALIDATED

    Source sequence(s)
    AL663037
    UniProtKB/Swiss-Prot
    Q3TPZ3, Q99LG1

  5. NM_001419374.1 → NP_001406303.1  transmembrane protein 51

    Status: VALIDATED

    Source sequence(s)
    AL663037
    UniProtKB/Swiss-Prot
    Q3TPZ3, Q99LG1

  6. NM_145402.4 → NP_663377.1  transmembrane protein 51

    See identical proteins and their annotated locations for NP_663377.1

    Status: VALIDATED

    Source sequence(s)
    AL663037
    Consensus CDS
    CCDS18886.1
    UniProtKB/Swiss-Prot
    Q3TPZ3, Q99LG1
    Related
    ENSMUSP00000042919.4, ENSMUST00000036572.4
    Conserved Domains (1) summary
    pfam15345
    Location:7 → 236
    TMEM51; Transmembrane protein 51

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    141758301..141811985 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011250227.2 → XP_011248529.1  transmembrane protein 51 isoform X1

    See identical proteins and their annotated locations for XP_011248529.1

    UniProtKB/Swiss-Prot
    Q3TPZ3, Q99LG1
    Conserved Domains (1) summary
    pfam15345
    Location:7 → 236
    TMEM51; Transmembrane protein 51

  2. XM_006538715.5 → XP_006538778.1  transmembrane protein 51 isoform X1

    See identical proteins and their annotated locations for XP_006538778.1

    UniProtKB/Swiss-Prot
    Q3TPZ3, Q99LG1
    Conserved Domains (1) summary
    pfam15345
    Location:7 → 236
    TMEM51; Transmembrane protein 51
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q99LG1.1 GenPept UniProtKB/Swiss-Prot:Q99LG1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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