U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Zfp879 zinc finger protein 879 [ Mus musculus (house mouse) ]

Gene ID: 214779, updated on 11-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
Zfp879provided by MGI
Official Full Name
zinc finger protein 879provided by MGI
Primary source
MGI:MGI:3053099
See related
Ensembl:ENSMUSG00000044296 AllianceGenome:MGI:3053099
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Znf879
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in embryo mesenchyme; genitourinary system; and limb segment. Orthologous to human ZNF879 (zinc finger protein 879). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
11 B1.3; 11 30.93 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (50719821..50732414, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (50828994..50841587, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 2 Neighboring gene predicted gene, 51860 Neighboring gene STARR-seq mESC enhancer starr_29408 Neighboring gene zinc finger protein 354C Neighboring gene STARR-positive B cell enhancer ABC_E6979 Neighboring gene glutamate receptor, metabotropic 6 Neighboring gene zinc finger protein 454

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
  2. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  3. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
  4. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

Go to the top of the page Help

Homology

Clone Names

  • 9630041N07Rik

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
zinc finger protein 879
Names
novel zinc finger protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001290779.1 → NP_001277708.1  zinc finger protein 879 isoform 2

    See identical proteins and their annotated locations for NP_001277708.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in its 5' UTR, lacks part of the 5' coding region, and uses a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    AK036152, BC118537, BF457823
    Consensus CDS
    CCDS70178.1
    UniProtKB/TrEMBL
    Q147Z4
    Related
    ENSMUSP00000104761.2, ENSMUST00000109133.2
    Conserved Domains (3) summary
    COG5048
    Location:132 → 485
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:301 → 321
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:453 → 478
    zf-H2C2_2; Zinc-finger double domain

  2. NM_173387.3 → NP_775563.1  zinc finger protein 879 isoform 1

    See identical proteins and their annotated locations for NP_775563.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK036152, BF457823
    Consensus CDS
    CCDS24638.1
    UniProtKB/Swiss-Prot
    Q8BI99
    Related
    ENSMUSP00000061782.2, ENSMUST00000049625.2
    Conserved Domains (6) summary
    smart00349
    Location:14 → 70
    KRAB; krueppel associated box
    COG5048
    Location:205 → 558
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:374 → 394
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:204 → 226
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:14 → 53
    KRAB; KRAB box
    pfam13465
    Location:526 → 551
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    50719821..50732414 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030245779.1 → XP_030101639.1  zinc finger protein 879 isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:14 → 70
    KRAB; krueppel associated box
    COG5048
    Location:201 → 554
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:370 → 390
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BI99.1 GenPept UniProtKB/Swiss-Prot:Q8BI99

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous