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Pdxk pyridoxal (pyridoxine, vitamin B6) kinase [ Mus musculus (house mouse) ]

Gene ID: 216134, updated on 23-Jun-2021

Summary

Official Symbol
Pdxkprovided by MGI
Official Full Name
pyridoxal (pyridoxine, vitamin B6) kinaseprovided by MGI
Primary source
MGI:MGI:1351869
See related
Ensembl:ENSMUSG00000032788
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C77999; AA119688; 2310036D04Rik
Expression
Ubiquitous expression in ovary adult (RPKM 41.8), kidney adult (RPKM 40.5) and 25 other tissues See more
Orthologs
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Genomic context

See Pdxk in Genome Data Viewer
Location:
10 C1; 10 39.72 cM
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (78272581..78300782, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (78436747..78464948, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (77899492..77927693, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene cystatin B Neighboring gene microRNA 6410 Neighboring gene microRNA 6908 Neighboring gene predicted gene, 30232 Neighboring gene olfactory receptor 1358 Neighboring gene predicted gene, 47944

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding ISO
Inferred from Sequence Orthology
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables lithium ion binding ISO
Inferred from Sequence Orthology
more info
 
enables magnesium ion binding ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables potassium ion binding ISO
Inferred from Sequence Orthology
more info
 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
enables pyridoxal binding ISO
Inferred from Sequence Orthology
more info
 
enables pyridoxal kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables pyridoxal kinase activity ISO
Inferred from Sequence Orthology
more info
 
enables pyridoxal phosphate binding ISO
Inferred from Sequence Orthology
more info
 
enables small molecule binding ISO
Inferred from Sequence Orthology
more info
 
enables sodium ion binding ISO
Inferred from Sequence Orthology
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
involved_in pyridoxal 5'-phosphate salvage IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in pyridoxal 5'-phosphate salvage ISO
Inferred from Sequence Orthology
more info
 
involved_in pyridoxal phosphate biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
pyridoxal kinase
Names
pyridoxine kinase
NP_742146.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172134.2NP_742146.1  pyridoxal kinase

    See identical proteins and their annotated locations for NP_742146.1

    Status: VALIDATED

    Source sequence(s)
    BC027745, BC032171, BI143426
    Consensus CDS
    CCDS23965.1
    UniProtKB/Swiss-Prot
    Q8K183
    Related
    ENSMUSP00000038540.9, ENSMUST00000041616.15
    Conserved Domains (1) summary
    cl00192
    Location:6304
    ribokinase_pfkB_like; ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    78272581..78300782 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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