Format

Send to:

Choose Destination

Ilvbl ilvB (bacterial acetolactate synthase)-like [ Mus musculus (house mouse) ]

Gene ID: 216136, updated on 23-Jun-2021

Summary

Official Symbol
Ilvblprovided by MGI
Official Full Name
ilvB (bacterial acetolactate synthase)-likeprovided by MGI
Primary source
MGI:MGI:1351911
See related
Ensembl:ENSMUSG00000032763
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AI415009; 5830463I21
Expression
Ubiquitous expression in thymus adult (RPKM 37.8), duodenum adult (RPKM 32.2) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Ilvbl in Genome Data Viewer
Location:
10 C1; 10 39.72 cM
Exon count:
18
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (78410178..78420336)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (78574344..78584502)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (78037245..78047247)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase 4a1 pseudogene Neighboring gene vomeronasal 2, receptor, pseudogene 92 Neighboring gene synapse defective 1, Rho GTPase, homolog 1 (C. elegans) Neighboring gene predicted gene, 30346

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables acetolactate synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables flavin adenine dinucleotide binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables thiamine pyrophosphate binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in fatty acid alpha-oxidation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within fatty acid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in isoleucine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in valine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of acetolactate synthase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
2-hydroxyacyl-CoA lyase 2
Names
acetolactate synthase-like protein
ilvB-like protein
NP_001346230.1
NP_001346231.1
NP_001346232.1
NP_776112.1
XP_011241702.1
XP_030100875.1
XP_030100876.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001359301.1NP_001346230.1  2-hydroxyacyl-CoA lyase 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC153887, AI842669, BC056459, BY231452
    Conserved Domains (1) summary
    cl28198
    Location:63596
    IlvB; Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino acid transport and metabolism, Coenzyme transport and metabolism]
  2. NM_001359302.1NP_001346231.1  2-hydroxyacyl-CoA lyase 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AI842669, AK133553, AK146075
    Consensus CDS
    CCDS23966.1
    Related
    ENSMUSP00000151263.2, ENSMUST00000218885.2
    Conserved Domains (1) summary
    PRK05858
    Location:53586
    PRK05858; acetolactate synthase
  3. NM_001359303.1NP_001346232.1  2-hydroxyacyl-CoA lyase 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AK133553, AK143918
    Consensus CDS
    CCDS88046.1
    Related
    ENSMUSP00000151480.2, ENSMUST00000218271.2
    Conserved Domains (1) summary
    PRK05858
    Location:53361
    PRK05858; acetolactate synthase
  4. NM_173751.4NP_776112.1  2-hydroxyacyl-CoA lyase 2 isoform 2

    See identical proteins and their annotated locations for NP_776112.1

    Status: VALIDATED

    Source sequence(s)
    BC056459, CD768274, CK789563
    Consensus CDS
    CCDS23966.1
    UniProtKB/Swiss-Prot
    Q8BU33
    Related
    ENSMUSP00000101023.4, ENSMUST00000105384.5
    Conserved Domains (1) summary
    PRK05858
    Location:53586
    PRK05858; acetolactate synthase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    78410178..78420336
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011243400.3XP_011241702.1  2-hydroxyacyl-CoA lyase 2 isoform X2

    See identical proteins and their annotated locations for XP_011241702.1

    UniProtKB/Swiss-Prot
    Q8BU33
    Conserved Domains (1) summary
    PRK05858
    Location:53586
    PRK05858; acetolactate synthase
  2. XM_030245015.2XP_030100875.1  2-hydroxyacyl-CoA lyase 2 isoform X1

    Conserved Domains (1) summary
    PRK05858
    Location:65598
    PRK05858; acetolactate synthase
  3. XM_030245016.2XP_030100876.1  2-hydroxyacyl-CoA lyase 2 isoform X3

    Conserved Domains (1) summary
    PRK05858
    Location:65373
    PRK05858; acetolactate synthase
Support Center