Format

Send to:

Choose Destination

Rufy1 RUN and FYVE domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 216724, updated on 23-Jun-2021

Summary

Official Symbol
Rufy1provided by MGI
Official Full Name
RUN and FYVE domain containing 1provided by MGI
Primary source
MGI:MGI:2429762
See related
Ensembl:ENSMUSG00000020375
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ra; Rabip4; ZFYVE1; ZFYVE12; 3000002E04Rik
Expression
Ubiquitous expression in frontal lobe adult (RPKM 5.9), adrenal adult (RPKM 5.7) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Rufy1 in Genome Data Viewer
Location:
11; 11 B1.3
Exon count:
21
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (50280113..50322101, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (50389286..50431274, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (50202805..50244613, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53701 Neighboring gene microRNA 804 Neighboring gene chibby family member 3 Neighboring gene heterogeneous nuclear ribonucleoprotein H1 Neighboring gene predicted gene, 53702 Neighboring gene predicted gene, 36763

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables SH2 domain binding ISO
Inferred from Sequence Orthology
more info
 
enables SH3 domain binding ISO
Inferred from Sequence Orthology
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables lipid binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within endocytosis IEA
Inferred from Electronic Annotation
more info
 
involved_in protein transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within protein transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within regulation of endocytosis IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of endocytosis ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within small GTPase mediated signal transduction IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
NOT located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
located_in endosome ISO
Inferred from Sequence Orthology
more info
 
is_active_in intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
NOT located_in late endosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
RUN and FYVE domain-containing protein 1
Names
FYVE-finger containing protein
Rab4a interacting protein
rab4-interacting protein

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172557.3NP_766145.1  RUN and FYVE domain-containing protein 1

    See identical proteins and their annotated locations for NP_766145.1

    Status: VALIDATED

    Source sequence(s)
    AK046625, AK046633, BQ176179
    Consensus CDS
    CCDS24635.1
    UniProtKB/Swiss-Prot
    Q8BIJ7
    Related
    ENSMUSP00000020643.4, ENSMUST00000020643.4
    Conserved Domains (3) summary
    cd15758
    Location:638708
    FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
    pfam02759
    Location:151274
    RUN; RUN domain
    cl02073
    Location:444589
    DUF3422; Protein of unknown function (DUF3422)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    50280113..50322101 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006532841.5XP_006532904.1  RUN and FYVE domain-containing protein 1 isoform X1

    Conserved Domains (3) summary
    TIGR02168
    Location:237540
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd15758
    Location:545615
    FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
    pfam02759
    Location:58179
    RUN; RUN domain
  2. XM_017314442.2XP_017169931.1  RUN and FYVE domain-containing protein 1 isoform X2

    Conserved Domains (1) summary
    pfam02759
    Location:151272
    RUN; RUN domain

RNA

  1. XR_001779949.2 RNA Sequence

  2. XR_004936914.1 RNA Sequence

  3. XR_004936913.1 RNA Sequence

Support Center