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Dlgap5 DLG associated protein 5 [ Mus musculus (house mouse) ]

Gene ID: 218977, updated on 23-Jun-2021

Summary

Official Symbol
Dlgap5provided by MGI
Official Full Name
DLG associated protein 5provided by MGI
Primary source
MGI:MGI:2183453
See related
Ensembl:ENSMUSG00000037544
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Hu; Dlg; Dlg7; Hurp; Dap-5; C77459; C86398; mKIAA0008
Expression
Biased expression in liver E14 (RPKM 20.5), liver E14.5 (RPKM 17.2) and 10 other tissues See more
Orthologs
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Genomic context

See Dlgap5 in Genome Data Viewer
Location:
14 C1; 14 24.6 cM
Exon count:
19
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (47625236..47655864, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (47387779..47418407, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (48007454..48038082, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 52166 Neighboring gene lectin, galactose binding, soluble 3 Neighboring gene ribosomal protein S15 pseudogene Neighboring gene F-box protein 34 Neighboring gene predicted gene, 35166

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
 
involved_in centrosome localization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in chromosome segregation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in kinetochore assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in mitotic spindle organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in signaling IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in centriolar satellite ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
is_active_in spindle pole centrosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in spindle pole centrosome ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
disks large-associated protein 5
Names
discs, large homolog 7
discs, large homolog-associated protein 5
hepatoma up-regulated protein homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_144553.2NP_653136.2  disks large-associated protein 5

    See identical proteins and their annotated locations for NP_653136.2

    Status: VALIDATED

    Source sequence(s)
    AB076696, AC123665, AK085882
    Consensus CDS
    CCDS26987.1
    UniProtKB/Swiss-Prot
    Q8K4R9
    UniProtKB/TrEMBL
    A0A0R4J0G7
    Related
    ENSMUSP00000040416.4, ENSMUST00000043296.10
    Conserved Domains (1) summary
    pfam03359
    Location:397543
    GKAP; Guanylate-kinase-associated protein (GKAP) protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    47625236..47655864 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006518835.5XP_006518898.1  disks large-associated protein 5 isoform X3

    Conserved Domains (1) summary
    pfam03359
    Location:399543
    GKAP; Guanylate-kinase-associated protein (GKAP) protein
  2. XM_006518833.2XP_006518896.1  disks large-associated protein 5 isoform X1

    Conserved Domains (1) summary
    pfam03359
    Location:387531
    GKAP; Guanylate-kinase-associated protein (GKAP) protein
  3. XM_006518834.2XP_006518897.1  disks large-associated protein 5 isoform X2

    Related
    ENSMUSP00000153953.2, ENSMUST00000180299.8
    Conserved Domains (1) summary
    pfam03359
    Location:399543
    GKAP; Guanylate-kinase-associated protein (GKAP) protein

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001145949.1: Suppressed sequence

    Description
    NM_001145949.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein, and the transcript appears incompletely processed at its 3' end.
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