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Tspan7 tetraspanin 7 [ Mus musculus (house mouse) ]

Gene ID: 21912, updated on 23-Jun-2021

Summary

Official Symbol
Tspan7provided by MGI
Official Full Name
tetraspanin 7provided by MGI
Primary source
MGI:MGI:1298407
See related
Ensembl:ENSMUSG00000058254
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
T; A1; A15; PE3; Mxs1; PE31; Cd231; TALLA; Tm4sf; R74651; Tm4sf2; AI323365; 1200014P11Rik
Expression
Biased expression in cortex adult (RPKM 421.3), frontal lobe adult (RPKM 387.8) and 14 other tissues See more
Orthologs
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Genomic context

See Tspan7 in Genome Data Viewer
Location:
X; X A1.1
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (10351355..10462843)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (10485116..10596604)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (10062242..10173730)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene ferritin light chain pseudogene Neighboring gene predicted gene, 54081 Neighboring gene ubiquitin-conjugating enzyme E2I pseudogene Neighboring gene lactate dehydrogenase A pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
tetraspanin-7
Names
TALLA homolog
cell surface glycoprotein A15
transmembrane 4 superfamily member 2
tspan-7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019634.2NP_062608.2  tetraspanin-7

    See identical proteins and their annotated locations for NP_062608.2

    Status: VALIDATED

    Source sequence(s)
    AI854904, AK004776, BY238972
    Consensus CDS
    CCDS30016.1
    UniProtKB/Swiss-Prot
    Q62283
    Related
    ENSMUSP00000075692.7, ENSMUST00000076354.13
    Conserved Domains (2) summary
    cd03161
    Location:110213
    TM4SF2_6_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), TM4SF2_6_like subfamily. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
    pfam00335
    Location:15237
    Tetraspannin; Tetraspanin family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    10351355..10462843
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036161904.1XP_036017797.1  tetraspanin-7 isoform X1

    Conserved Domains (1) summary
    cd03161
    Location:24127
    TM4SF2_6_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), TM4SF2_6_like subfamily. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
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