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OR5D14 olfactory receptor family 5 subfamily D member 14 [ Homo sapiens (human) ]

Gene ID: 219436, updated on 5-Mar-2024

Summary

Official Symbol
OR5D14provided by HGNC
Official Full Name
olfactory receptor family 5 subfamily D member 14provided by HGNC
Primary source
HGNC:HGNC:15281
See related
Ensembl:ENSG00000186113 AllianceGenome:HGNC:15281
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR11-141; OR11-150
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

Location:
11q11
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (55795556..55796500)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (55733880..55734824)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (55563032..55563976)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 5 subfamily D member 13 Neighboring gene olfactory receptor family 5 subfamily D member 15 pseudogene Neighboring gene olfactory receptor family 5 subfamily L member 1 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:55585370-55585533 Neighboring gene olfactory receptor family 5 subfamily D member 18

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables odorant binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in detection of chemical stimulus involved in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
 
involved_in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 5D14
Names
olfactory receptor OR11-141
olfactory receptor OR11-150

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004735.1NP_001004735.1  olfactory receptor 5D14

    See identical proteins and their annotated locations for NP_001004735.1

    Status: PROVISIONAL

    Source sequence(s)
    AC036111
    Consensus CDS
    CCDS31508.1
    UniProtKB/Swiss-Prot
    Q6IF69, Q6IFD4, Q8NGL3, Q96RB5
    UniProtKB/TrEMBL
    A0A126GWM1
    Related
    ENSP00000334456.1, ENST00000335605.1
    Conserved Domains (2) summary
    pfam00001
    Location:43292
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:33307
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    55795556..55796500
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    55733880..55734824
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)