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Pglyrp1 peptidoglycan recognition protein 1 [ Mus musculus (house mouse) ]

Gene ID: 21946, updated on 23-Jun-2021

Summary

Official Symbol
Pglyrp1provided by MGI
Official Full Name
peptidoglycan recognition protein 1provided by MGI
Primary source
MGI:MGI:1345092
See related
Ensembl:ENSMUSG00000030413
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
PG; Tag; Tas; PGRP; Tag7; Tnfs; Tasg7; PGRP-S; Pglyrp; Tnfsf3l
Expression
Biased expression in colon adult (RPKM 543.4), duodenum adult (RPKM 351.9) and 6 other tissues See more
Orthologs
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Genomic context

See Pglyrp1 in Genome Data Viewer
Location:
7; 7 A3
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (18618615..18624363)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (18884690..18890438)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (19470039..19475787)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein K pseudogene Neighboring gene MHC I like leukocyte 2 Neighboring gene coiled-coil domain containing 61 Neighboring gene NOVA alternative splicing regulator 2 Neighboring gene predicted gene, 38952

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables N-acetylmuramoyl-L-alanine amidase activity IEA
Inferred from Electronic Annotation
more info
 
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 
enables peptidoglycan binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables peptidoglycan binding ISO
Inferred from Sequence Orthology
more info
 
enables peptidoglycan immune receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables peptidoglycan immune receptor activity ISO
Inferred from Sequence Orthology
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in antimicrobial humoral immune response mediated by antimicrobial peptide ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within apoptotic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within biological process involved in interaction with host IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in defense response to Gram-positive bacterium IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in defense response to Gram-positive bacterium ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within defense response to bacterium IEA
Inferred from Electronic Annotation
more info
 
involved_in detection of bacterium IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in detection of bacterium ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within immune system process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within innate immune response IEA
Inferred from Electronic Annotation
more info
 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 
involved_in killing of cells of other organism ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within negative regulation of inflammatory response IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of interferon-gamma production IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of natural killer cell differentiation involved in immune response IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in peptidoglycan catabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within response to bacterium IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
peptidoglycan recognition protein 1
Names
cytokine tag7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009402.2NP_033428.1  peptidoglycan recognition protein 1 precursor

    See identical proteins and their annotated locations for NP_033428.1

    Status: PROVISIONAL

    Source sequence(s)
    AC153651
    Consensus CDS
    CCDS20881.1
    UniProtKB/Swiss-Prot
    O88593
    UniProtKB/TrEMBL
    Q4FK86
    Related
    ENSMUSP00000032573.7, ENSMUST00000032573.8
    Conserved Domains (1) summary
    smart00701
    Location:20160
    PGRP; Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    18618615..18624363
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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