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Tub tubby bipartite transcription factor [ Mus musculus (house mouse) ]

Gene ID: 22141, updated on 12-Aug-2019

Summary

Official Symbol
Tubprovided by MGI
Official Full Name
tubby bipartite transcription factorprovided by MGI
Primary source
MGI:MGI:2651573
See related
Ensembl:ENSMUSG00000031028
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
rd5; tub
Expression
Biased expression in CNS E18 (RPKM 40.9), whole brain E14.5 (RPKM 30.4) and 8 other tissues See more
Orthologs

Genomic context

See Tub in Genome Data Viewer
Location:
7 E3; 7 57.21 cM
Exon count:
12
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (109010880..109034459)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (116154394..116177973)

Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 39067 Neighboring gene predicted gene, 32309 Neighboring gene RIC3 acetylcholine receptor chaperone Neighboring gene U6 spliceosomal RNA Neighboring gene predicted gene 44781 Neighboring gene LIM domain only 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Spontaneous (1) 
  • Targeted (1)  1 citation
  • Chemically induced (ENU) (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
G protein-coupled receptor binding ISO
Inferred from Sequence Orthology
more info
PubMed 
intraciliary transport particle A binding ISO
Inferred from Sequence Orthology
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
intraciliary transport ISO
Inferred from Sequence Orthology
more info
PubMed 
phagocytosis IEA
Inferred from Electronic Annotation
more info
 
phagocytosis, recognition IDA
Inferred from Direct Assay
more info
PubMed 
phagocytosis, recognition IMP
Inferred from Mutant Phenotype
more info
PubMed 
photoreceptor cell maintenance IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of phagocytosis ISO
Inferred from Sequence Orthology
more info
 
protein localization to ciliary membrane ISO
Inferred from Sequence Orthology
more info
 
protein localization to cilium IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein localization to cilium IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein localization to photoreceptor outer segment IMP
Inferred from Mutant Phenotype
more info
PubMed 
receptor localization to non-motile cilium IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of G protein-coupled receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to stimulus IEA
Inferred from Electronic Annotation
more info
 
retina development in camera-type eye IMP
Inferred from Mutant Phenotype
more info
PubMed 
sensory perception of sound IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cilium IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cilium ISO
Inferred from Sequence Orthology
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
PubMed 
cytosol IMP
Inferred from Mutant Phenotype
more info
PubMed 
extracellular region IDA
Inferred from Direct Assay
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
PubMed 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
tubby protein
Names
retinal degeneration 5
tubby candidate

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021885.4NP_068685.1  tubby protein

    See identical proteins and their annotated locations for NP_068685.1

    Status: VALIDATED

    Source sequence(s)
    AK147700, BC096554
    Consensus CDS
    CCDS21732.1
    UniProtKB/Swiss-Prot
    P50586
    UniProtKB/TrEMBL
    Q4VA41
    Related
    ENSMUSP00000033341.5, ENSMUST00000033341.11
    Conserved Domains (2) summary
    pfam01167
    Location:257498
    Tub; Tub family
    pfam16322
    Location:29226
    Tub_N; Tubby N-terminal

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000073.6 Reference GRCm38.p6 C57BL/6J

    Range
    109010880..109034459
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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