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Tuba3b tubulin, alpha 3B [ Mus musculus (house mouse) ]

Gene ID: 22147, updated on 8-Feb-2024

Summary

Official Symbol
Tuba3bprovided by MGI
Official Full Name
tubulin, alpha 3Bprovided by MGI
Primary source
MGI:MGI:1095408
See related
Ensembl:ENSMUSG00000067338 AllianceGenome:MGI:1095408
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
M[a]7; Tuba7
Summary
Is expressed in nervous system and sensory organ. Human ortholog(s) of this gene implicated in keratoconus. Orthologous to human TUBA3D (tubulin alpha 3d). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 866.7) See more
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Genomic context

Location:
6 G3; 6 77.62 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (145561689..145567203)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (145615963..145621477)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene lamin tail domain containing 1 Neighboring gene predicted gene 15499 Neighboring gene predicted gene, 25373 Neighboring gene predicted gene 15704 Neighboring gene Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 Neighboring gene STARR-positive B cell enhancer mm9_chr6:145778656-145778957 Neighboring gene predicted gene, 38927

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
tubulin alpha-3 chain
Names
alpha-tubulin 3/7
alpha-tubulin isotype M-alpha-3/7
tubulin alpha-3/alpha-7 chain
tubulin, alpha 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009449.3NP_033475.1  tubulin alpha-3 chain

    See identical proteins and their annotated locations for NP_033475.1

    Status: VALIDATED

    Source sequence(s)
    BC050769, BF152752, CK137160
    Consensus CDS
    CCDS39707.1
    UniProtKB/Swiss-Prot
    P05214
    UniProtKB/TrEMBL
    Q3TIZ0, Q5FW91
    Related
    ENSMUSP00000084713.7, ENSMUST00000087445.7
    Conserved Domains (1) summary
    PTZ00335
    Location:1440
    PTZ00335; tubulin alpha chain; Provisional

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    145561689..145567203
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)