Format

Send to:

Choose Destination

Ugcg UDP-glucose ceramide glucosyltransferase [ Mus musculus (house mouse) ]

Gene ID: 22234, updated on 16-Oct-2021

Summary

Official Symbol
Ugcgprovided by MGI
Official Full Name
UDP-glucose ceramide glucosyltransferaseprovided by MGI
Primary source
MGI:MGI:1332243
See related
Ensembl:ENSMUSG00000028381
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ugcgl; C80537; Epcs21; GlcT-1; AU043821
Expression
Ubiquitous expression in CNS E18 (RPKM 20.2), whole brain E14.5 (RPKM 18.2) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Ugcg in Genome Data Viewer
Location:
4 32.44 cM; 4 B3
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (59189452..59222833)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (59189507..59222833)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (59202422..59235705)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene shortage in chiasmata 1 Neighboring gene predicted gene, 35527 Neighboring gene ribosomal protein SA, pseudogene 11 Neighboring gene predicted gene 12596 Neighboring gene predicted gene, 35578

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (6)  1 citation
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ceramide glucosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ceramide glucosyltransferase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables ceramide glucosyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables dihydroceramide glucosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi membrane ISO
Inferred from Sequence Orthology
more info
 
located_in integral component of membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
ceramide glucosyltransferase
Names
GCS
UDP-glucose:N-acylsphingosine D-glucosyltransferase
ectoplacental cone, invasive trophoblast giant cells, extraembryonic ectoderm and chorion sequence 21
glucosylceramide synthase
NP_035803.1
XP_006537848.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011673.3NP_035803.1  ceramide glucosyltransferase

    See identical proteins and their annotated locations for NP_035803.1

    Status: PROVISIONAL

    Source sequence(s)
    AL808112
    Consensus CDS
    CCDS18219.1
    UniProtKB/Swiss-Prot
    O88693
    Related
    ENSMUSP00000030074.8, ENSMUST00000030074.8
    Conserved Domains (1) summary
    cd02520
    Location:51280
    Glucosylceramide_synthase; Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid synthesis

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    59189452..59222833
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006537785.5XP_006537848.1  ceramide glucosyltransferase isoform X1

    Conserved Domains (1) summary
    cd02520
    Location:51284
    Glucosylceramide_synthase; Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid synthesis
Support Center