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Vim vimentin [ Mus musculus (house mouse) ]

Gene ID: 22352, updated on 28-Nov-2021

Summary

Official Symbol
Vimprovided by MGI
Official Full Name
vimentinprovided by MGI
Primary source
MGI:MGI:98932
See related
Ensembl:ENSMUSG00000026728
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Expression
Broad expression in subcutaneous fat pad adult (RPKM 622.6), mammary gland adult (RPKM 524.7) and 24 other tissues See more
Orthologs
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Genomic context

See Vim in Genome Data Viewer
Location:
2 A1; 2 10.04 cM
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (13579122..13587637)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (13574311..13582826)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (13495938..13504453)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 54102 Neighboring gene predicted gene 9875 Neighboring gene ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 Neighboring gene 3-hydroxyacyl-CoA dehydratase 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC102095

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables double-stranded RNA binding ISO
Inferred from Sequence Orthology
more info
PubMed 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables keratin filament binding ISO
Inferred from Sequence Orthology
more info
 
enables kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein domain specific binding ISO
Inferred from Sequence Orthology
more info
 
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables protein phosphatase 2A binding ISO
Inferred from Sequence Orthology
more info
 
enables scaffold protein binding ISO
Inferred from Sequence Orthology
more info
 
enables structural constituent of cytoskeleton IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables structural constituent of cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
enables structural constituent of eye lens IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within Bergmann glial cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within SMAD protein signal transduction IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within astrocyte development IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within cellular response to interferon-gamma IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cellular response to lipopolysaccharide ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to muramyl dipeptide ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within intermediate filament organization IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in intermediate filament organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within intermediate filament-based process IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within lens fiber cell development IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within negative regulation of neuron projection development IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in positive regulation of collagen biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of glial cell proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of translation ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of Schwann cell migration ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of axonogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of mRNA stability ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in axon ISO
Inferred from Sequence Orthology
more info
 
located_in cell body ISO
Inferred from Sequence Orthology
more info
 
located_in cell leading edge IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell projection IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell projection ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytoskeleton ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in intermediate filament IDA
Inferred from Direct Assay
more info
PubMed 
located_in intermediate filament ISO
Inferred from Sequence Orthology
more info
 
located_in intermediate filament cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in neuron projection IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in peroxisome ISO
Inferred from Sequence Orthology
more info
 
located_in phagocytic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
part_of polysome ISO
Inferred from Sequence Orthology
more info
 
part_of ribonucleoprotein complex ISO
Inferred from Sequence Orthology
more info
 
located_in type III intermediate filament TAS
Traceable Author Statement
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011701.4NP_035831.2  vimentin

    See identical proteins and their annotated locations for NP_035831.2

    Status: VALIDATED

    Source sequence(s)
    AK133726
    Consensus CDS
    CCDS15696.1
    UniProtKB/Swiss-Prot
    P20152
    UniProtKB/TrEMBL
    Q5FWJ3
    Related
    ENSMUSP00000028062.3, ENSMUST00000028062.8
    Conserved Domains (2) summary
    pfam00038
    Location:102410
    Filament; Intermediate filament protein
    pfam04732
    Location:14101
    Filament_head; Intermediate filament head (DNA binding) region

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    13579122..13587637
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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