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Crb3 crumbs family member 3 [ Mus musculus (house mouse) ]

Gene ID: 224912, updated on 23-Nov-2021

Summary

Official Symbol
Crb3provided by MGI
Official Full Name
crumbs family member 3provided by MGI
Primary source
MGI:MGI:2670904
See related
Ensembl:ENSMUSG00000044279
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AU015179; AU041752; 5730439B18
Expression
Broad expression in duodenum adult (RPKM 28.1), colon adult (RPKM 24.9) and 17 other tissues See more
Orthologs
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Genomic context

See Crb3 in Genome Data Viewer
Location:
17; 17 D
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (57368583..57372920)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (57062201..57065918)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (57201700..57205341)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 25, member 41 Neighboring gene solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 Neighboring gene DENN/MADD domain containing 1C Neighboring gene tubulin, beta 4A class IVA

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables SH3 domain binding ISO
Inferred from Sequence Orthology
more info
 
enables protein domain specific binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in apical part of cell IDA
Inferred from Direct Assay
more info
PubMed 
located_in apical plasma membrane ISA
Inferred from Sequence Alignment
more info
PubMed 
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 
located_in cell junction ISO
Inferred from Sequence Orthology
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 
part_of subapical complex IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001347408.1NP_001334337.1  protein crumbs homolog 3 isoform 2

    Status: VALIDATED

    Source sequence(s)
    BP769883, CT571247
    Consensus CDS
    CCDS84327.1
    UniProtKB/Swiss-Prot
    Q8QZT4
    Related
    ENSMUSP00000125760.2, ENSMUST00000169543.8
    Conserved Domains (1) summary
    pfam15345
    Location:2109
    TMEM51; Transmembrane protein 51
  2. NM_001359813.1NP_001346742.1  protein crumbs homolog 3 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AK077528, AK167279, BP769883
    Consensus CDS
    CCDS28924.1
    Related
    ENSMUSP00000071729.4, ENSMUST00000071826.10
  3. NM_001359814.1NP_001346743.1  protein crumbs homolog 3 isoform 2

    Status: VALIDATED

    Source sequence(s)
    CT571247
    Consensus CDS
    CCDS84327.1
    Conserved Domains (1) summary
    pfam15345
    Location:2109
    TMEM51; Transmembrane protein 51
  4. NM_177638.5NP_808306.1  protein crumbs homolog 3 isoform 1 precursor

    See identical proteins and their annotated locations for NP_808306.1

    Status: VALIDATED

    Source sequence(s)
    CT571247
    Consensus CDS
    CCDS28924.1
    UniProtKB/Swiss-Prot
    Q8QZT4
    Related
    ENSMUSP00000094902.4, ENSMUST00000097299.10

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    57368583..57372920
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036160561.1XP_036016454.1  protein crumbs homolog 3 isoform X1

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