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Svil supervillin [ Mus musculus (house mouse) ]

Gene ID: 225115, updated on 23-Jun-2021

Summary

Official Symbol
Svilprovided by MGI
Official Full Name
supervillinprovided by MGI
Primary source
MGI:MGI:2147319
See related
Ensembl:ENSMUSG00000024236
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AU024053; B430302E16Rik
Expression
Broad expression in bladder adult (RPKM 33.3), heart adult (RPKM 16.5) and 20 other tissues See more
Orthologs
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Genomic context

See Svil in Genome Data Viewer
Location:
18; 18 A1
Exon count:
44
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (4920497..5119293)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (4920467..5119293)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (5046587..5119291)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted gene 10556 Neighboring gene predicted gene, 34269 Neighboring gene predicted gene, 41659 Neighboring gene predicted gene, 34326 Neighboring gene predicted gene, 53196 Neighboring gene predicted gene, 26682

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables actin filament binding ISO
Inferred from Sequence Orthology
more info
 
enables phosphatidylinositol-4,5-bisphosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in actin filament severing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in actin polymerization or depolymerization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in barbed-end actin filament capping IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 
involved_in skeletal muscle tissue development ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
located_in cell junction IEA
Inferred from Electronic Annotation
more info
 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in costamere ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
supervillin
Names
archvillin
p205/p250

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001347449.1NP_001334378.1  supervillin isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks multiple in-frame exons in the 5' coding region, compared to variant 1. The encoded isoform (b) is shorter than isoform a.
    Source sequence(s)
    AC115928, AC124770, BP761556
    Consensus CDS
    CCDS84352.1
    UniProtKB/Swiss-Prot
    Q8K4L3
    Conserved Domains (6) summary
    smart00153
    Location:17311766
    VHP; Villin headpiece domain
    cd11280
    Location:11151215
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:14311536
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:9941086
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:12981411
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:15531675
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  2. NM_153153.3NP_694793.1  supervillin isoform a

    See identical proteins and their annotated locations for NP_694793.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (a).
    Source sequence(s)
    AC115928, AF317422, AK161114, BC099602
    Consensus CDS
    CCDS37720.1
    UniProtKB/Swiss-Prot
    Q8K4L3
    UniProtKB/TrEMBL
    Q3TTX5
    Related
    ENSMUSP00000025079.10, ENSMUST00000025079.16
    Conserved Domains (6) summary
    smart00153
    Location:21352170
    VHP; Villin headpiece domain
    cd11280
    Location:15191619
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:18351940
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:13981494
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:17021815
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19572079
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    4920497..5119293
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036161085.1XP_036016978.1  supervillin isoform X12

    Conserved Domains (4) summary
    cd11280
    Location:15361636
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:14151507
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:17191832
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:18521925
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  2. XM_006525791.3XP_006525854.1  supervillin isoform X1

    See identical proteins and their annotated locations for XP_006525854.1

    Conserved Domains (6) summary
    smart00153
    Location:21522187
    VHP; Villin headpiece domain
    cd11280
    Location:15361636
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:18521957
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:14151511
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:17191832
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19742096
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  3. XM_036161072.1XP_036016965.1  supervillin isoform X3

    Conserved Domains (6) summary
    smart00153
    Location:21362171
    VHP; Villin headpiece domain
    cd11280
    Location:15201620
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:18361941
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:13991495
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:17031816
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19582080
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  4. XM_030250413.2XP_030106273.1  supervillin isoform X13

    Conserved Domains (7) summary
    smart00153
    Location:18341869
    VHP; Villin headpiece domain
    cd11280
    Location:12181318
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:15341639
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:10971189
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:14011514
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    PTZ00441
    Location:177335
    PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
    cl15697
    Location:16561778
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  5. XM_030250414.2XP_030106274.1  supervillin isoform X14

    Conserved Domains (6) summary
    smart00153
    Location:17791814
    VHP; Villin headpiece domain
    cd11280
    Location:11631263
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:14791584
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:10421138
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:13461459
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:16011723
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  6. XM_036161087.1XP_036016980.1  supervillin isoform X17

    Related
    ENSMUSP00000119287.2, ENSMUST00000143254.8
    Conserved Domains (6) summary
    smart00153
    Location:17311766
    VHP; Villin headpiece domain
    cd11280
    Location:11151215
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:14311536
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:9941086
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:12981411
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:15531675
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  7. XM_006525789.3XP_006525852.1  supervillin isoform X1

    See identical proteins and their annotated locations for XP_006525852.1

    Conserved Domains (6) summary
    smart00153
    Location:21522187
    VHP; Villin headpiece domain
    cd11280
    Location:15361636
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:18521957
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:14151511
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:17191832
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19742096
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  8. XM_011246879.3XP_011245181.1  supervillin isoform X5

    Conserved Domains (6) summary
    smart00153
    Location:21202155
    VHP; Villin headpiece domain
    cd11280
    Location:15041604
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:18201925
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:13831475
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:16871800
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19422064
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  9. XM_011246876.3XP_011245178.1  supervillin isoform X2

    Conserved Domains (6) summary
    smart00153
    Location:21512186
    VHP; Villin headpiece domain
    cd11280
    Location:15351635
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:18511956
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:14141510
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:17181831
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19732095
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  10. XM_006525792.3XP_006525855.1  supervillin isoform X1

    See identical proteins and their annotated locations for XP_006525855.1

    Conserved Domains (6) summary
    smart00153
    Location:21522187
    VHP; Villin headpiece domain
    cd11280
    Location:15361636
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:18521957
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:14151511
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:17191832
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19742096
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  11. XM_036161071.1XP_036016964.1  supervillin isoform X1

    Conserved Domains (6) summary
    smart00153
    Location:21522187
    VHP; Villin headpiece domain
    cd11280
    Location:15361636
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:18521957
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:14151511
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:17191832
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19742096
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  12. XM_011246877.4XP_011245179.1  supervillin isoform X3

    Conserved Domains (6) summary
    smart00153
    Location:21362171
    VHP; Villin headpiece domain
    cd11280
    Location:15201620
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:18361941
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:13991495
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:17031816
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19582080
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  13. XM_036161078.1XP_036016971.1  supervillin isoform X6

    Conserved Domains (6) summary
    smart00153
    Location:21042139
    VHP; Villin headpiece domain
    cd11280
    Location:14881588
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:18041909
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:13671459
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:16711784
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19262048
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  14. XM_011246881.3XP_011245183.1  supervillin isoform X8

    Conserved Domains (6) summary
    smart00153
    Location:20972132
    VHP; Villin headpiece domain
    cd11280
    Location:14811581
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:17971902
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:13601456
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:16641777
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19192041
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  15. XM_036161081.1XP_036016974.1  supervillin isoform X10

    Conserved Domains (6) summary
    smart00153
    Location:20812116
    VHP; Villin headpiece domain
    cd11280
    Location:14651565
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:17811886
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:13441440
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:16481761
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19032025
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  16. XM_011246878.4XP_011245180.1  supervillin isoform X4

    See identical proteins and their annotated locations for XP_011245180.1

    UniProtKB/Swiss-Prot
    Q8K4L3
    Related
    ENSMUSP00000115078.2, ENSMUST00000126977.8
    Conserved Domains (6) summary
    smart00153
    Location:21352170
    VHP; Villin headpiece domain
    cd11280
    Location:15191619
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:18351940
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:13981494
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:17021815
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19572079
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  17. XM_011246880.3XP_011245182.1  supervillin isoform X7

    Conserved Domains (6) summary
    smart00153
    Location:21032138
    VHP; Villin headpiece domain
    cd11280
    Location:14871587
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:18031908
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:13661458
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:16701783
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19252047
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  18. XM_036161083.1XP_036016976.1  supervillin isoform X11

    Conserved Domains (6) summary
    smart00153
    Location:20802115
    VHP; Villin headpiece domain
    cd11280
    Location:14641564
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:17801885
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:13431439
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:16471760
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19022024
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  19. XM_011246882.4XP_011245184.1  supervillin isoform X13

    Conserved Domains (7) summary
    smart00153
    Location:18341869
    VHP; Villin headpiece domain
    cd11280
    Location:12181318
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:15341639
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:10971189
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:14011514
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    PTZ00441
    Location:177335
    PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
    cl15697
    Location:16561778
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  20. XM_006525800.5XP_006525863.1  supervillin isoform X14

    See identical proteins and their annotated locations for XP_006525863.1

    Conserved Domains (6) summary
    smart00153
    Location:17791814
    VHP; Villin headpiece domain
    cd11280
    Location:11631263
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:14791584
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:10421138
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:13461459
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:16011723
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  21. XM_017317865.3XP_017173354.1  supervillin isoform X15

    Conserved Domains (6) summary
    smart00153
    Location:17631798
    VHP; Villin headpiece domain
    cd11280
    Location:11471247
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:14631568
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:10261122
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:13301443
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:15851707
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  22. XM_011246884.3XP_011245186.1  supervillin isoform X16

    Conserved Domains (6) summary
    smart00153
    Location:17471782
    VHP; Villin headpiece domain
    cd11280
    Location:11311231
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:14471552
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:10101102
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:13141427
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:15691691
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  23. XM_006525801.5XP_006525864.1  supervillin isoform X14

    See identical proteins and their annotated locations for XP_006525864.1

    Conserved Domains (6) summary
    smart00153
    Location:17791814
    VHP; Villin headpiece domain
    cd11280
    Location:11631263
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:14791584
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:10421138
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:13461459
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:16011723
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  24. XM_030250415.2XP_030106275.1  supervillin isoform X17

    Conserved Domains (6) summary
    smart00153
    Location:17311766
    VHP; Villin headpiece domain
    cd11280
    Location:11151215
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:14311536
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:9941086
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:12981411
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:15531675
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  25. XM_036161086.1XP_036016979.1  supervillin isoform X14

    Conserved Domains (6) summary
    smart00153
    Location:17791814
    VHP; Villin headpiece domain
    cd11280
    Location:11631263
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:14791584
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:10421138
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:13461459
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:16011723
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  26. XM_006525790.1XP_006525853.1  supervillin isoform X1

    See identical proteins and their annotated locations for XP_006525853.1

    Conserved Domains (6) summary
    smart00153
    Location:21522187
    VHP; Villin headpiece domain
    cd11280
    Location:15361636
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:18521957
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:14151511
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:17191832
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19742096
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  27. XM_006525793.5XP_006525856.1  supervillin isoform X1

    See identical proteins and their annotated locations for XP_006525856.1

    Conserved Domains (6) summary
    smart00153
    Location:21522187
    VHP; Villin headpiece domain
    cd11280
    Location:15361636
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:18521957
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:14151511
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:17191832
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19742096
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  28. XM_036161075.1XP_036016968.1  supervillin isoform X4

    Related
    ENSMUSP00000147843.2, ENSMUST00000210707.2
    Conserved Domains (6) summary
    smart00153
    Location:21352170
    VHP; Villin headpiece domain
    cd11280
    Location:15191619
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:18351940
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:13981494
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:17021815
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19572079
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  29. XM_006525794.5XP_006525857.1  supervillin isoform X1

    See identical proteins and their annotated locations for XP_006525857.1

    Conserved Domains (6) summary
    smart00153
    Location:21522187
    VHP; Villin headpiece domain
    cd11280
    Location:15361636
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:18521957
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:14151511
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:17191832
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19742096
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  30. XM_036161073.1XP_036016966.1  supervillin isoform X3

    Conserved Domains (6) summary
    smart00153
    Location:21362171
    VHP; Villin headpiece domain
    cd11280
    Location:15201620
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:18361941
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:13991495
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:17031816
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19582080
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  31. XM_036161076.1XP_036016969.1  supervillin isoform X4

    Related
    ENSMUSP00000119803.2, ENSMUST00000140448.8
    Conserved Domains (6) summary
    smart00153
    Location:21352170
    VHP; Villin headpiece domain
    cd11280
    Location:15191619
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:18351940
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:13981494
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:17021815
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19572079
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  32. XM_036161074.1XP_036016967.1  supervillin isoform X3

    Conserved Domains (6) summary
    smart00153
    Location:21362171
    VHP; Villin headpiece domain
    cd11280
    Location:15201620
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:18361941
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:13991495
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:17031816
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19582080
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  33. XM_036161077.1XP_036016970.1  supervillin isoform X4

    Conserved Domains (6) summary
    smart00153
    Location:21352170
    VHP; Villin headpiece domain
    cd11280
    Location:15191619
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:18351940
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:13981494
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:17021815
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19572079
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  34. XM_036161080.1XP_036016973.1  supervillin isoform X9

    Conserved Domains (6) summary
    smart00153
    Location:20962131
    VHP; Villin headpiece domain
    cd11280
    Location:14801580
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:17961901
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:13591455
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:16631776
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19182040
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  35. XM_036161079.1XP_036016972.1  supervillin isoform X6

    Conserved Domains (6) summary
    smart00153
    Location:21042139
    VHP; Villin headpiece domain
    cd11280
    Location:14881588
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:18041909
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:13671459
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:16711784
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19262048
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  36. XM_036161082.1XP_036016975.1  supervillin isoform X10

    Conserved Domains (6) summary
    smart00153
    Location:20812116
    VHP; Villin headpiece domain
    cd11280
    Location:14651565
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:17811886
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:13441440
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:16481761
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19032025
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
  37. XM_036161084.1XP_036016977.1  supervillin isoform X11

    Conserved Domains (6) summary
    smart00153
    Location:20802115
    VHP; Villin headpiece domain
    cd11280
    Location:14641564
    gelsolin_like; Tandemly repeated domains found in gelsolin, severin, villin, and related proteins
    cd11288
    Location:17801885
    gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
    cd11289
    Location:13431439
    gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
    cd11293
    Location:16471760
    gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
    cl15697
    Location:19022024
    ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_178046.3: Suppressed sequence

    Description
    NM_178046.3: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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