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Rnf112 ring finger protein 112 [ Mus musculus (house mouse) ]

Gene ID: 22671, updated on 23-Jun-2021

Summary

Official Symbol
Rnf112provided by MGI
Official Full Name
ring finger protein 112provided by MGI
Primary source
MGI:MGI:106611
See related
Ensembl:ENSMUSG00000010086
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
bf; bfp; neu; Zfp17; ZNF179; Zfp179; neurolastin
Expression
Biased expression in cerebellum adult (RPKM 117.7), cortex adult (RPKM 98.5) and 5 other tissues See more
Orthologs
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Genomic context

See Rnf112 in Genome Data Viewer
Location:
11 B2; 11 37.96 cM
Exon count:
16
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (61339243..61345014, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (61448417..61454188, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (61261944..61267388, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene nuclear encoded tRNA trytophan 5 (anticodon CCA) Neighboring gene predicted gene 12271 Neighboring gene microfibrillar-associated protein 4 Neighboring gene mitogen-activated protein kinase 7

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables GTP binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables GTPase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein self-association IDA
Inferred from Direct Assay
more info
PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin protein ligase activity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in cell body IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell junction IEA
Inferred from Electronic Annotation
more info
 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
located_in endosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in extrinsic component of membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear body IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in postsynaptic density IDA
Inferred from Direct Assay
more info
PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 
located_in synaptic vesicle IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
RING finger protein 112
Names
brain finger protein
zinc finger protein 179
NP_001277953.1
NP_001346059.1
NP_033574.2
XP_006533241.1
XP_006533243.1
XP_006533244.1
XP_006533245.1
XP_006533246.1
XP_006533247.1
XP_006533248.1
XP_017169993.1
XP_017169994.1
XP_030101793.1
XP_036012528.1
XP_036012529.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001291024.1NP_001277953.1  RING finger protein 112 isoform 2

    See identical proteins and their annotated locations for NP_001277953.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon and uses alternate in-frame splice sites in the 5' coding region, compared to variant 3. It encodes isoform 2, which lacks two separate internal segments and is shorter, compared to isoform 3.
    Source sequence(s)
    BC013139, BY599807, CJ148450
    Consensus CDS
    CCDS78960.1
    UniProtKB/Swiss-Prot
    Q96DY5
    Related
    ENSMUSP00000099722.4, ENSMUST00000102661.4
    Conserved Domains (2) summary
    cd01851
    Location:163361
    GBP; Guanylate-binding protein (GBP) family (N-terminal domain)
    cd16538
    Location:55102
    RING-HC_RNF112; RING finger, HC subclass, found in RING finger protein 112 (RNF112) and similar proteins
  2. NM_001359130.1NP_001346059.1  RING finger protein 112 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3).
    Source sequence(s)
    AK131651, BC013139, BE945765, BY237309
    Consensus CDS
    CCDS88167.1
    Related
    ENSMUSP00000059903.8, ENSMUST00000060255.14
    Conserved Domains (2) summary
    cd16538
    Location:78125
    RING-HC_RNF112; RING finger, HC subclass, found in RING finger protein 112 (RNF112) and similar proteins
    cl38936
    Location:186409
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  3. NM_009548.3NP_033574.2  RING finger protein 112 isoform 1

    See identical proteins and their annotated locations for NP_033574.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) uses alternate in-frame splice sites in the 5' coding region, compared to variant 3. It encodes isoform 1, which lacks an internal segment and is shorter, compared to isoform 3.
    Source sequence(s)
    BC013139, BY599807, CJ148450
    Consensus CDS
    CCDS24812.1
    UniProtKB/Swiss-Prot
    Q96DY5
    Related
    ENSMUSP00000056464.8, ENSMUST00000054927.14
    Conserved Domains (2) summary
    cd01851
    Location:186384
    GBP; Guanylate-binding protein (GBP) family (N-terminal domain)
    cd16538
    Location:78125
    RING-HC_RNF112; RING finger, HC subclass, found in RING finger protein 112 (RNF112) and similar proteins

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    61339243..61345014 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017314504.1XP_017169993.1  RING finger protein 112 isoform X6

    Conserved Domains (2) summary
    cd01851
    Location:185383
    GBP; Guanylate-binding protein (GBP) family (N-terminal domain)
    cd16538
    Location:78125
    RING-HC_RNF112; RING finger, HC subclass, found in RING finger protein 112 (RNF112) and similar proteins
  2. XM_006533180.2XP_006533243.1  RING finger protein 112 isoform X2

    Conserved Domains (2) summary
    cd16538
    Location:78125
    RING-HC_RNF112; RING finger, HC subclass, found in RING finger protein 112 (RNF112) and similar proteins
    cl38936
    Location:185408
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  3. XM_036156635.1XP_036012528.1  RING finger protein 112 isoform X4

    Conserved Domains (2) summary
    cd16538
    Location:55102
    RING-HC_RNF112; RING finger, HC subclass, found in RING finger protein 112 (RNF112) and similar proteins
    cl38936
    Location:162385
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  4. XM_006533183.2XP_006533246.1  RING finger protein 112 isoform X7

    See identical proteins and their annotated locations for XP_006533246.1

    UniProtKB/Swiss-Prot
    Q96DY5
    Conserved Domains (2) summary
    cd01851
    Location:163361
    GBP; Guanylate-binding protein (GBP) family (N-terminal domain)
    cd16538
    Location:55102
    RING-HC_RNF112; RING finger, HC subclass, found in RING finger protein 112 (RNF112) and similar proteins
  5. XM_006533181.2XP_006533244.1  RING finger protein 112 isoform X3

    Conserved Domains (2) summary
    cd16538
    Location:55102
    RING-HC_RNF112; RING finger, HC subclass, found in RING finger protein 112 (RNF112) and similar proteins
    cl38936
    Location:163386
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  6. XM_017314505.1XP_017169994.1  RING finger protein 112 isoform X9

    Conserved Domains (1) summary
    cd01851
    Location:50248
    GBP; Guanylate-binding protein (GBP) family (N-terminal domain)
  7. XM_006533185.2XP_006533248.1  RING finger protein 112 isoform X8

    See identical proteins and their annotated locations for XP_006533248.1

    Conserved Domains (1) summary
    cl38936
    Location:50273
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  8. XM_006533182.5XP_006533245.1  RING finger protein 112 isoform X5

    See identical proteins and their annotated locations for XP_006533245.1

    UniProtKB/Swiss-Prot
    Q96DY5
    Conserved Domains (2) summary
    cd01851
    Location:186384
    GBP; Guanylate-binding protein (GBP) family (N-terminal domain)
    cd16538
    Location:78125
    RING-HC_RNF112; RING finger, HC subclass, found in RING finger protein 112 (RNF112) and similar proteins
  9. XM_006533178.2XP_006533241.1  RING finger protein 112 isoform X1

    See identical proteins and their annotated locations for XP_006533241.1

    UniProtKB/Swiss-Prot
    Q96DY5
    Conserved Domains (2) summary
    cd16538
    Location:78125
    RING-HC_RNF112; RING finger, HC subclass, found in RING finger protein 112 (RNF112) and similar proteins
    cl38936
    Location:186409
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  10. XM_030245933.1XP_030101793.1  RING finger protein 112 isoform X9

    Conserved Domains (1) summary
    cd01851
    Location:50248
    GBP; Guanylate-binding protein (GBP) family (N-terminal domain)
  11. XM_006533184.2XP_006533247.1  RING finger protein 112 isoform X8

    See identical proteins and their annotated locations for XP_006533247.1

    Conserved Domains (1) summary
    cl38936
    Location:50273
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  12. XM_036156636.1XP_036012529.1  RING finger protein 112 isoform X10

    Conserved Domains (1) summary
    cl38936
    Location:1161
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
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