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Zfpm2 zinc finger protein, multitype 2 [ Mus musculus (house mouse) ]

Gene ID: 22762, updated on 27-Jul-2021

Summary

Official Symbol
Zfpm2provided by MGI
Official Full Name
zinc finger protein, multitype 2provided by MGI
Primary source
MGI:MGI:1334444
See related
Ensembl:ENSMUSG00000022306
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
FOG; FOG-; FOG2; FOG-2; B330005D23Rik
Expression
Broad expression in cerebellum adult (RPKM 6.0), CNS E14 (RPKM 3.9) and 17 other tissues See more
Orthologs
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Genomic context

See Zfpm2 in Genome Data Viewer
Location:
15 B3.1; 15 15.74 cM
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (40518438..40967988)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (40655042..41104592)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (40486588..40936138)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene 16294 Neighboring gene actin related protein 2/3 complex, subunit 1B pseudogene Neighboring gene mbt domain containing 1 pseudogene Neighboring gene peptidylprolyl isomerase A pseudogene 25 Neighboring gene predicted gene, 33353 Neighboring gene leucine rich repeat and sterile alpha motif containing 1 pseudogene Neighboring gene predicted gene, 46502 Neighboring gene predicted gene, 33557

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA polymerase II-specific DNA-binding transcription factor binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transcription coactivator activity ISO
Inferred from Sequence Orthology
more info
 
NOT enables transcription corepressor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables transcription corepressor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables transcription factor binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in atrioventricular valve morphogenesis TAS
Traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within cardiac muscle tissue development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cardiac muscle tissue morphogenesis TAS
Traceable Author Statement
more info
PubMed 
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within embryonic organ development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within embryonic organ development ISO
Inferred from Sequence Orthology
more info
PubMed 
involved_in heart development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within heart development IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within heart development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within in utero embryonic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within lung development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mitral valve formation TAS
Traceable Author Statement
more info
PubMed 
involved_in negative regulation of cell death IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of fat cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of fat cell differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of female gonad development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
NOT acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of transcription, DNA-templated TAS
Traceable Author Statement
more info
PubMed 
involved_in outflow tract morphogenesis TAS
Traceable Author Statement
more info
PubMed 
involved_in outflow tract septum morphogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cardiac muscle cell proliferation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in positive regulation of male gonad development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of transcription, DNA-templated IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of transcription, DNA-templated TAS
Traceable Author Statement
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
involved_in right ventricular cardiac muscle tissue morphogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in tricuspid valve formation TAS
Traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within vasculogenesis IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within vasculogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in vasculogenesis involved in coronary vascular morphogenesis TAS
Traceable Author Statement
more info
PubMed 
involved_in ventricular septum morphogenesis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
zinc finger protein ZFPM2
Names
Friend of GATA 2
friend of GATA protein 2
friend of GATA-1 2
friend of GATA-2
mFOG-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001356998.1NP_001343927.1  zinc finger protein ZFPM2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC101996, AC102004, AC158556, AC163008
    Related
    ENSMUSP00000155094.2, ENSMUST00000230319.2
    Conserved Domains (2) summary
    sd00017
    Location:248267
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam15909
    Location:245349
    zf-C2H2_8; C2H2-type zinc ribbon
  2. NM_011766.5NP_035896.1  zinc finger protein ZFPM2 isoform 1

    See identical proteins and their annotated locations for NP_035896.1

    Status: VALIDATED

    Source sequence(s)
    AC101996, AC102004, AC158556, AC163008
    Consensus CDS
    CCDS27447.1
    UniProtKB/Swiss-Prot
    Q8CCH7
    Related
    ENSMUSP00000051335.5, ENSMUST00000053467.6
    Conserved Domains (2) summary
    sd00017
    Location:301320
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam15909
    Location:298388
    zf-C2H2_8; C2H2-type zinc ribbon

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    40518438..40967988
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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