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Zhx1 zinc fingers and homeoboxes 1 [ Mus musculus (house mouse) ]

Gene ID: 22770, updated on 23-Jun-2021

Summary

Official Symbol
Zhx1provided by MGI
Official Full Name
zinc fingers and homeoboxes 1provided by MGI
Primary source
MGI:MGI:109271
See related
Ensembl:ENSMUSG00000022361
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Expression
Ubiquitous expression in bladder adult (RPKM 9.2), CNS E18 (RPKM 8.7) and 25 other tissues See more
Orthologs
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Genomic context

See Zhx1 in Genome Data Viewer
Location:
15; 15 D1
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (57910399..57939904, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (58047003..58076508, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (57878558..57908044, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53893 Neighboring gene predicted gene, 22299 Neighboring gene ATPase family, AAA domain containing 2 Neighboring gene small nuclear ribonucleoprotein Sm D2-like Neighboring gene WDYHV motif containing 1 Neighboring gene predicted gene, 23475

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA4149, mKIAA4149, 3110006I21Rik

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables DNA-binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
zinc fingers and homeoboxes protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001042438.2NP_001035903.1  zinc fingers and homeoboxes protein 1

    See identical proteins and their annotated locations for NP_001035903.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC113292, AK220508, BC054543, CJ093421, CN533009
    Consensus CDS
    CCDS27488.1
    UniProtKB/Swiss-Prot
    P70121
    UniProtKB/TrEMBL
    Q5DTL2
    Related
    ENSMUSP00000105797.2, ENSMUST00000110168.8
    Conserved Domains (3) summary
    smart00389
    Location:665716
    HOX; Homeodomain
    cd00086
    Location:468523
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam11569
    Location:785821
    Homez; Homeodomain leucine-zipper encoding, Homez
  2. NM_009572.4NP_033598.2  zinc fingers and homeoboxes protein 1

    See identical proteins and their annotated locations for NP_033598.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) differs in the 5' UTR, compared to variant 2. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC113292, AK220508, BC054543, CJ093421
    Consensus CDS
    CCDS27488.1
    UniProtKB/Swiss-Prot
    P70121
    UniProtKB/TrEMBL
    Q5DTL2
    Related
    ENSMUSP00000066201.7, ENSMUST00000070143.13
    Conserved Domains (3) summary
    smart00389
    Location:665716
    HOX; Homeodomain
    cd00086
    Location:468523
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam11569
    Location:785821
    Homez; Homeodomain leucine-zipper encoding, Homez

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    57910399..57939904 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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