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Prrc2b proline-rich coiled-coil 2B [ Mus musculus (house mouse) ]

Gene ID: 227723, updated on 8-Aug-2021

Summary

Official Symbol
Prrc2bprovided by MGI
Official Full Name
proline-rich coiled-coil 2Bprovided by MGI
Primary source
MGI:MGI:1923304
See related
Ensembl:ENSMUSG00000039262
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Bat; Bat2l; Bat2l1; AI173903; mKIAA0515; D430039P21; 5830434P21Rik
Expression
Ubiquitous expression in whole brain E14.5 (RPKM 35.1), ovary adult (RPKM 32.2) and 28 other tissues See more
Orthologs
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Genomic context

See Prrc2b in Genome Data Viewer
Location:
2; 2 B
Exon count:
33
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (32041002..32124549)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (32151031..32234537)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (32006668..32090057)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene phospholipid phosphatase 7 (inactive) Neighboring gene VISTA enhancer mm194 Neighboring gene predicted gene, 22192 Neighboring gene predicted gene, 25632 Neighboring gene protein-O-mannosyltransferase 1 Neighboring gene uridine-cytidine kinase 1 Neighboring gene 60S ribosomal protein L36 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within in utero embryonic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
protein PRRC2B
Names
HLA-B-associated transcript 2-like 1
proline-rich coiled-coil protein 2B
protein BAT2-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159634.1NP_001153106.1  protein PRRC2B isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK147677, BC055116, BP753788
    Consensus CDS
    CCDS50565.1
    UniProtKB/Swiss-Prot
    Q7TPM1
    UniProtKB/TrEMBL
    F8WHT3
    Related
    ENSMUSP00000064892.9, ENSMUST00000069817.15
    Conserved Domains (2) summary
    pfam07001
    Location:1189
    BAT2_N; BAT2 N-terminus
    pfam07223
    Location:19322189
    DUF1421; Protein of unknown function (DUF1421)
  2. NM_172661.3NP_766249.2  protein PRRC2B isoform 2

    See identical proteins and their annotated locations for NP_766249.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the central coding region, lacks an alternate exon in the 3' coding region that results in a frameshift of the C-terminus, and uses an alternate in-frame splice site in the coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, includes an extra amino acid, and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AK147677, BC055116, BP753788
    Consensus CDS
    CCDS15907.1
    UniProtKB/Swiss-Prot
    Q7TPM1
    Related
    ENSMUSP00000035734.8, ENSMUST00000036691.14
    Conserved Domains (2) summary
    pfam03153
    Location:12611441
    TFIIA; Transcription factor IIA, alpha/beta subunit
    pfam07001
    Location:1189
    BAT2_N; BAT2 N-terminus

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    32041002..32124549
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006497948.5XP_006498011.1  protein PRRC2B isoform X1

    Conserved Domains (2) summary
    PHA03247
    Location:17412176
    PHA03247; large tegument protein UL36; Provisional
    pfam07001
    Location:1189
    BAT2_N; BAT2 N-terminus
  2. XM_006497951.5XP_006498014.1  protein PRRC2B isoform X4

    Conserved Domains (2) summary
    pfam09606
    Location:18022123
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam07001
    Location:1189
    BAT2_N; BAT2 N-terminus
  3. XM_030249906.2XP_030105766.1  protein PRRC2B isoform X5

    Conserved Domains (2) summary
    pfam09606
    Location:18012122
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam07001
    Location:1189
    BAT2_N; BAT2 N-terminus
  4. XM_006497949.5XP_006498012.1  protein PRRC2B isoform X2

    Conserved Domains (2) summary
    PHA03247
    Location:17112146
    PHA03247; large tegument protein UL36; Provisional
    pfam07001
    Location:1189
    BAT2_N; BAT2 N-terminus
  5. XM_006497950.5XP_006498013.1  protein PRRC2B isoform X3

    Conserved Domains (2) summary
    PHA03247
    Location:17102145
    PHA03247; large tegument protein UL36; Provisional
    pfam07001
    Location:1189
    BAT2_N; BAT2 N-terminus
  6. XM_006497952.5XP_006498015.1  protein PRRC2B isoform X6

    Related
    ENSMUSP00000116429.2, ENSMUST00000132459.8
    Conserved Domains (2) summary
    PHA03247
    Location:10541489
    PHA03247; large tegument protein UL36; Provisional
    pfam07001
    Location:1189
    BAT2_N; BAT2 N-terminus
  7. XM_006497953.5XP_006498016.1  protein PRRC2B isoform X7

    See identical proteins and their annotated locations for XP_006498016.1

    Conserved Domains (2) summary
    PHA03247
    Location:10531488
    PHA03247; large tegument protein UL36; Provisional
    pfam07001
    Location:1189
    BAT2_N; BAT2 N-terminus
  8. XM_030249910.2XP_030105770.1  protein PRRC2B isoform X8

    Conserved Domains (2) summary
    PHA03247
    Location:10241459
    PHA03247; large tegument protein UL36; Provisional
    pfam07001
    Location:1189
    BAT2_N; BAT2 N-terminus
  9. XM_030249911.2XP_030105771.1  protein PRRC2B isoform X9

    Conserved Domains (2) summary
    PHA03247
    Location:10231458
    PHA03247; large tegument protein UL36; Provisional
    pfam07001
    Location:1189
    BAT2_N; BAT2 N-terminus
  10. XM_030249897.2XP_030105757.1  protein PRRC2B isoform X1

    Conserved Domains (2) summary
    PHA03247
    Location:17412176
    PHA03247; large tegument protein UL36; Provisional
    pfam07001
    Location:1189
    BAT2_N; BAT2 N-terminus
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