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Gca grancalcin [ Mus musculus (house mouse) ]

Gene ID: 227960, updated on 23-Jun-2021

Summary

Official Symbol
Gcaprovided by MGI
Official Full Name
grancalcinprovided by MGI
Primary source
MGI:MGI:1918521
See related
Ensembl:ENSMUSG00000026893
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AI573844; 5133401E04Rik
Expression
Ubiquitous expression in cortex adult (RPKM 6.2), frontal lobe adult (RPKM 5.7) and 28 other tissues See more
Orthologs
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Genomic context

See Gca in Genome Data Viewer
Location:
2; 2 C1.3
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (62494671..62524453)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (62664327..62694109)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (62502384..62532166)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene fibroblast activation protein Neighboring gene interferon induced with helicase C domain 1 Neighboring gene predicted gene, 39839 Neighboring gene soc-2 (suppressor of clear) homolog pseudogene Neighboring gene potassium voltage-gated channel, subfamily H (eag-related), member 7 Neighboring gene predicted gene, 22020 Neighboring gene predicted gene 13569

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables calcium ion binding ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol TAS
Traceable Author Statement
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145523.3NP_663498.1  grancalcin

    See identical proteins and their annotated locations for NP_663498.1

    Status: PROVISIONAL

    Source sequence(s)
    AK078915
    Consensus CDS
    CCDS16069.1
    UniProtKB/Swiss-Prot
    Q8VC88
    Related
    ENSMUSP00000028257.3, ENSMUST00000028257.3
    Conserved Domains (3) summary
    cd00051
    Location:67122
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam13499
    Location:128183
    EF-hand_7; EF-hand domain pair
    cl08302
    Location:97152
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    62494671..62524453
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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