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Klhl41 kelch-like 41 [ Mus musculus (house mouse) ]

Gene ID: 228003, updated on 6-Sep-2021

Summary

Official Symbol
Klhl41provided by MGI
Official Full Name
kelch-like 41provided by MGI
Primary source
MGI:MGI:2683854
See related
Ensembl:ENSMUSG00000075307
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm112; Kbtbd10; SARCOSIN
Expression
Biased expression in heart adult (RPKM 9.8), mammary gland adult (RPKM 7.3) and 6 other tissues See more
Orthologs
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Genomic context

See Klhl41 in Genome Data Viewer
Location:
2; 2 C2
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (69500464..69514583)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (69670120..69684239)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (69508177..69522296)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene low density lipoprotein receptor-related protein 2 Neighboring gene Bardet-Biedl syndrome 5 (human) Neighboring gene FAST kinase domains 1 Neighboring gene peptidyl-prolyl isomerase G (cyclophilin G)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
part_of Cul3-RING ubiquitin ligase complex ISO
Inferred from Sequence Orthology
more info
 
is_active_in M band IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in M band IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoskeleton IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in pseudopodium ISO
Inferred from Sequence Orthology
more info
 
located_in sarcoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
is_active_in sarcoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in sarcoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in sarcoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
kelch-like protein 41
Names
kelch repeat and BTB (POZ) domain containing 10
kelch repeat and BTB domain-containing protein 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081087.1NP_001074556.1  kelch-like protein 41

    See identical proteins and their annotated locations for NP_001074556.1

    Status: VALIDATED

    Source sequence(s)
    AL929083
    Consensus CDS
    CCDS38136.1
    UniProtKB/Swiss-Prot
    A2AUC9
    Related
    ENSMUSP00000097627.4, ENSMUST00000100050.4
    Conserved Domains (7) summary
    smart00612
    Location:346398
    Kelch; Kelch domain
    PHA03098
    Location:39578
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:388433
    Kelch; KELCH repeat [structural motif]
    pfam00651
    Location:23127
    BTB; BTB/POZ domain
    pfam01344
    Location:484529
    Kelch_1; Kelch motif
    pfam07707
    Location:147237
    BACK; BTB And C-terminal Kelch
    pfam13964
    Location:439485
    Kelch_6; Kelch motif

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    69500464..69514583
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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