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Madd MAP-kinase activating death domain [ Mus musculus (house mouse) ]

Gene ID: 228355, updated on 22-Aug-2021

Summary

Official Symbol
Maddprovided by MGI
Official Full Name
MAP-kinase activating death domainprovided by MGI
Primary source
MGI:MGI:2444672
See related
Ensembl:ENSMUSG00000040687
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
IG20; RabGEF; Rab3GEP; 9630059K23Rik
Expression
Broad expression in cerebellum adult (RPKM 20.7), cortex adult (RPKM 19.1) and 27 other tissues See more
Orthologs
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Genomic context

See Madd in Genome Data Viewer
Location:
2; 2 E1
Exon count:
37
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (90967705..91013404, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (91137360..91184006, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (90977517..91024025, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene spleen focus forming virus (SFFV) proviral integration oncogene Neighboring gene myosin binding protein C, cardiac Neighboring gene nuclear receptor subfamily 1, group H, member 3 Neighboring gene predicted gene, 23390 Neighboring gene acid phosphatase 2, lysosomal Neighboring gene damage specific DNA binding protein 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables guanyl-nucleotide exchange factor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in anterograde synaptic vesicle transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in anterograde synaptic vesicle transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within apoptotic process IEA
Inferred from Electronic Annotation
more info
 
involved_in execution phase of apoptosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in execution phase of apoptosis ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within negative regulation of apoptotic signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of growth hormone secretion ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of pancreatic amylase secretion ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of MAPK cascade ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of Rab protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of Rab protein signal transduction ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of apoptotic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of cell cycle IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of cell cycle ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of extrinsic apoptotic signaling pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of extrinsic apoptotic signaling pathway via death domain receptors ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in integral component of membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in synaptic vesicle ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
MAP kinase-activating death domain protein
Names
Rab3 GDP/GTP exchange protein
Rab3 GEP
insulinoma-glucagonoma protein 20
rab3 GDP/GTP exchange factor

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001177719.1NP_001171190.1  MAP kinase-activating death domain protein isoform 10

    Status: VALIDATED

    Description
    Transcript Variant: This variant (10) represents the longest transcript and encodes isoform 10.
    Source sequence(s)
    AK036347, AK122257, BC063386
    Consensus CDS
    CCDS50638.1
    UniProtKB/Swiss-Prot
    Q80U28
    UniProtKB/TrEMBL
    A2AGR0
    Related
    ENSMUSP00000097311.3, ENSMUST00000099723.9
    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  2. NM_001177720.1NP_001171191.1  MAP kinase-activating death domain protein isoform 11

    Status: VALIDATED

    Description
    Transcript Variant: This variant (11) lacks one coding exon, has two additional coding exons, and uses an alternate splice site, compared to variant 10. The resulting isoform (11) is longer and differs at several internal portions and the C-terminus, compared to isoform 10.
    Source sequence(s)
    BC042212, BC063386
    Consensus CDS
    CCDS50635.1
    UniProtKB/Swiss-Prot
    Q80U28
    UniProtKB/TrEMBL
    E9QN47
    Related
    ENSMUSP00000097313.3, ENSMUST00000099725.9
    Conserved Domains (4) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
    pfam15231
    Location:101150
    VCX_VCY; Variable charge X/Y family
  3. NM_145527.4NP_663502.3  MAP kinase-activating death domain protein isoform 9

    See identical proteins and their annotated locations for NP_663502.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9) lacks one exon and uses an alternate splice site in the coding region, compared to variant 10. The resulting isoform (9) differs at two internal portions, compared to isoform 10.
    Source sequence(s)
    AK036347, BC063386
    Consensus CDS
    CCDS38178.1
    UniProtKB/Swiss-Prot
    Q80U28
    UniProtKB/TrEMBL
    A0A0R4J1F4
    Related
    ENSMUSP00000107001.3, ENSMUST00000111370.9
    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    90967705..91013404 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030250251.2XP_030106111.1  MAP kinase-activating death domain protein isoform X33

    Conserved Domains (4) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
    pfam15231
    Location:101150
    VCX_VCY; Variable charge X/Y family
  2. XM_030250248.2XP_030106108.1  MAP kinase-activating death domain protein isoform X31

    Related
    ENSMUSP00000107004.2, ENSMUST00000111373.8
    Conserved Domains (4) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
    pfam15231
    Location:101150
    VCX_VCY; Variable charge X/Y family
  3. XM_030250247.2XP_030106107.1  MAP kinase-activating death domain protein isoform X30

    Conserved Domains (4) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
    pfam15231
    Location:101150
    VCX_VCY; Variable charge X/Y family
  4. XM_036161230.1XP_036017123.1  MAP kinase-activating death domain protein isoform X26

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  5. XM_030250245.2XP_030106105.1  MAP kinase-activating death domain protein isoform X23

    Related
    ENSMUSP00000107006.2, ENSMUST00000111375.8
    Conserved Domains (4) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
    pfam15231
    Location:101150
    VCX_VCY; Variable charge X/Y family
  6. XM_036161217.1XP_036017110.1  MAP kinase-activating death domain protein isoform X17

    Related
    ENSMUST00000125321.8
    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  7. XM_030250240.2XP_030106100.1  MAP kinase-activating death domain protein isoform X16

    Conserved Domains (4) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
    pfam15231
    Location:101150
    VCX_VCY; Variable charge X/Y family
  8. XM_030250238.2XP_030106098.1  MAP kinase-activating death domain protein isoform X15

    Related
    ENSMUSP00000107003.2, ENSMUST00000111372.8
    Conserved Domains (4) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
    pfam15231
    Location:101150
    VCX_VCY; Variable charge X/Y family
  9. XM_036161211.1XP_036017104.1  MAP kinase-activating death domain protein isoform X13

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  10. XM_030250227.2XP_030106087.1  MAP kinase-activating death domain protein isoform X11

    Related
    ENSMUSP00000107012.3, ENSMUST00000111381.9
    Conserved Domains (4) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
    pfam15231
    Location:101150
    VCX_VCY; Variable charge X/Y family
  11. XM_030250208.2XP_030106068.1  MAP kinase-activating death domain protein isoform X3

    Conserved Domains (4) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
    pfam15231
    Location:101150
    VCX_VCY; Variable charge X/Y family
  12. XM_030250220.2XP_030106080.1  MAP kinase-activating death domain protein isoform X8

    Conserved Domains (4) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
    pfam15231
    Location:101150
    VCX_VCY; Variable charge X/Y family
  13. XM_030250202.2XP_030106062.1  MAP kinase-activating death domain protein isoform X1

    Conserved Domains (4) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
    pfam15231
    Location:101150
    VCX_VCY; Variable charge X/Y family
  14. XM_036161224.1XP_036017117.1  MAP kinase-activating death domain protein isoform X24

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  15. XM_036161198.1XP_036017091.1  MAP kinase-activating death domain protein isoform X5

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  16. XM_036161257.1XP_036017150.1  MAP kinase-activating death domain protein isoform X47

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  17. XM_036161255.1XP_036017148.1  MAP kinase-activating death domain protein isoform X46

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  18. XM_030250257.2XP_030106117.1  MAP kinase-activating death domain protein isoform X48

    Related
    ENSMUSP00000107000.2, ENSMUST00000111369.8
    Conserved Domains (4) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
    pfam15231
    Location:101150
    VCX_VCY; Variable charge X/Y family
  19. XM_036161254.1XP_036017147.1  MAP kinase-activating death domain protein isoform X45

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  20. XM_036161253.1XP_036017146.1  MAP kinase-activating death domain protein isoform X44

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  21. XM_036161221.1XP_036017114.1  MAP kinase-activating death domain protein isoform X21

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  22. XM_036161250.1XP_036017143.1  MAP kinase-activating death domain protein isoform X42

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  23. XM_036161218.1XP_036017111.1  MAP kinase-activating death domain protein isoform X18

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  24. XM_036161248.1XP_036017141.1  MAP kinase-activating death domain protein isoform X41

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  25. XM_036161251.1XP_036017144.1  MAP kinase-activating death domain protein isoform X43

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  26. XM_036161219.1XP_036017112.1  MAP kinase-activating death domain protein isoform X19

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  27. XM_030250253.2XP_030106113.1  MAP kinase-activating death domain protein isoform X40

    Conserved Domains (4) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
    pfam15231
    Location:101150
    VCX_VCY; Variable charge X/Y family
  28. XM_036161244.1XP_036017137.1  MAP kinase-activating death domain protein isoform X39

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  29. XM_036161243.1XP_036017136.1  MAP kinase-activating death domain protein isoform X38

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  30. XM_036161213.1XP_036017106.1  MAP kinase-activating death domain protein isoform X14

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  31. XM_036161241.1XP_036017134.1  MAP kinase-activating death domain protein isoform X36

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  32. XM_036161240.1XP_036017133.1  MAP kinase-activating death domain protein isoform X35

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  33. XM_036161239.1XP_036017132.1  MAP kinase-activating death domain protein isoform X34

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  34. XM_030250236.2XP_030106096.1  MAP kinase-activating death domain protein isoform X12

    Related
    ENSMUSP00000107007.2, ENSMUST00000111376.8
    Conserved Domains (4) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
    pfam15231
    Location:101150
    VCX_VCY; Variable charge X/Y family
  35. XM_036161234.1XP_036017127.1  MAP kinase-activating death domain protein isoform X32

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  36. XM_030250225.2XP_030106085.1  MAP kinase-activating death domain protein isoform X10

    Conserved Domains (4) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
    pfam15231
    Location:101150
    VCX_VCY; Variable charge X/Y family
  37. XM_036161242.1XP_036017135.1  MAP kinase-activating death domain protein isoform X37

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  38. XM_030250246.2XP_030106106.1  MAP kinase-activating death domain protein isoform X29

    Conserved Domains (4) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
    pfam15231
    Location:101150
    VCX_VCY; Variable charge X/Y family
  39. XM_036161202.1XP_036017095.1  MAP kinase-activating death domain protein isoform X9

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  40. XM_036161231.1XP_036017124.1  MAP kinase-activating death domain protein isoform X27

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  41. XM_036161199.1XP_036017092.1  MAP kinase-activating death domain protein isoform X7

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  42. XM_036161232.1XP_036017125.1  MAP kinase-activating death domain protein isoform X28

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  43. XM_036161228.1XP_036017121.1  MAP kinase-activating death domain protein isoform X25

    Conserved Domains (3) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
  44. XM_030250217.2XP_030106077.1  MAP kinase-activating death domain protein isoform X6

    Conserved Domains (4) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
    pfam15231
    Location:101150
    VCX_VCY; Variable charge X/Y family
  45. XM_030250244.2XP_030106104.1  MAP kinase-activating death domain protein isoform X22

    Conserved Domains (4) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
    pfam15231
    Location:101150
    VCX_VCY; Variable charge X/Y family
  46. XM_030250209.2XP_030106069.1  MAP kinase-activating death domain protein isoform X4

    Conserved Domains (4) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
    pfam15231
    Location:101150
    VCX_VCY; Variable charge X/Y family
  47. XM_030250242.2XP_030106102.1  MAP kinase-activating death domain protein isoform X20

    Conserved Domains (4) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
    pfam15231
    Location:101150
    VCX_VCY; Variable charge X/Y family
  48. XM_030250207.2XP_030106067.1  MAP kinase-activating death domain protein isoform X2

    Related
    ENSMUSP00000077094.7, ENSMUST00000077941.13
    Conserved Domains (4) summary
    smart00801
    Location:485553
    dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
    smart00799
    Location:172401
    DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
    smart00800
    Location:797
    uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
    pfam15231
    Location:101150
    VCX_VCY; Variable charge X/Y family

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001177721.1: Suppressed sequence

    Description
    NM_001177721.1: This RefSeq was permanently suppressed because currently there is not sufficient data to support this transcript.
  2. NM_001177722.1: Suppressed sequence

    Description
    NM_001177722.1: This RefSeq was permanently suppressed because currently there is not sufficient data to support this transcript.
  3. NM_001177723.1: Suppressed sequence

    Description
    NM_001177723.1: This RefSeq was permanently suppressed because currently there is not sufficient data to support this transcript.
  4. NM_001177724.1: Suppressed sequence

    Description
    NM_001177724.1: This RefSeq was permanently suppressed because currently there is not sufficient data to support this transcript.
  5. NM_001177725.1: Suppressed sequence

    Description
    NM_001177725.1: This RefSeq was permanently suppressed because currently there is not sufficient data to support this transcript.
  6. NM_001177726.1: Suppressed sequence

    Description
    NM_001177726.1: This RefSeq was permanently suppressed because currently there is not sufficient data to support this transcript.
  7. NM_001177727.1: Suppressed sequence

    Description
    NM_001177727.1: This RefSeq was permanently suppressed because currently there is not sufficient data to support this transcript.
  8. NM_001177728.1: Suppressed sequence

    Description
    NM_001177728.1: This RefSeq was permanently suppressed because currently there is not sufficient data to support this transcript.
  9. NM_001177729.1: Suppressed sequence

    Description
    NM_001177729.1: This RefSeq was permanently suppressed because currently there is not sufficient data to support this transcript.
  10. NM_178369.1: Suppressed sequence

    Description
    NM_178369.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
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