Format

Send to:

Choose Destination

Tmeff1 transmembrane protein with EGF-like and two follistatin-like domains 1 [ Mus musculus (house mouse) ]

Gene ID: 230157, updated on 23-Jun-2021

Summary

Official Symbol
Tmeff1provided by MGI
Official Full Name
transmembrane protein with EGF-like and two follistatin-like domains 1provided by MGI
Primary source
MGI:MGI:1926810
See related
Ensembl:ENSMUSG00000028347
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tr1; TR-1; M7365; A830033E11
Expression
Biased expression in CNS E18 (RPKM 70.4), CNS E14 (RPKM 69.8) and 12 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Tmeff1 in Genome Data Viewer
Location:
4; 4 B1
Exon count:
10
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (48584583..48663132)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (48585071..48663132)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (48598065..48676003)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene inversin Neighboring gene testis expressed gene 10 Neighboring gene Myb/SANT-like DNA-binding domain containing 3 Neighboring gene predicted gene 12439 Neighboring gene caveolae associated 4

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in animal organ morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
involved_in neuromuscular junction development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in receptor clustering IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in tissue development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
tomoregulin-1
Names
transmembrane protein with EGF-like and one follistatin-like domain

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001356272.1NP_001343201.1  tomoregulin-1 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    BB619168, BC057598, BM947087, BU709349, CF532023, CN534217
    Related
    ENSMUSP00000121740.2, ENSMUST00000130834.8
    Conserved Domains (2) summary
    smart00280
    Location:91135
    KAZAL; Kazal type serine protease inhibitors
    cl28647
    Location:268304
    PHA02887; EGF-like protein; Provisional
  2. NM_021436.3NP_067411.1  tomoregulin-1 isoform 2 precursor

    See identical proteins and their annotated locations for NP_067411.1

    Status: VALIDATED

    Source sequence(s)
    AW491640, BB619168, BC057598, BM947087, BU709349, CN534217
    Consensus CDS
    CCDS18168.1
    UniProtKB/Swiss-Prot
    Q6PFE7
    Related
    ENSMUSP00000030032.7, ENSMUST00000030032.13
    Conserved Domains (2) summary
    PHA02887
    Location:267303
    PHA02887; EGF-like protein; Provisional
    smart00280
    Location:91135
    KAZAL; Kazal type serine protease inhibitors

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    48584583..48663132
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006537837.3XP_006537900.1  tomoregulin-1 isoform X1

    UniProtKB/Swiss-Prot
    Q6PFE7
    Conserved Domains (2) summary
    PHA02887
    Location:266302
    PHA02887; EGF-like protein; Provisional
    smart00280
    Location:91135
    KAZAL; Kazal type serine protease inhibitors
  2. XM_006537838.2XP_006537901.1  tomoregulin-1 isoform X2

    Conserved Domains (2) summary
    PHA02887
    Location:265301
    PHA02887; EGF-like protein; Provisional
    smart00280
    Location:91135
    KAZAL; Kazal type serine protease inhibitors
Support Center