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Crybg2 crystallin beta-gamma domain containing 2 [ Mus musculus (house mouse) ]

Gene ID: 230806, updated on 5-Mar-2024

Summary

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Official Symbol
Crybg2provided by MGI
Official Full Name
crystallin beta-gamma domain containing 2provided by MGI
Primary source
MGI:MGI:1334463
See related
Ensembl:ENSMUSG00000012123 AllianceGenome:MGI:1334463
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Aim1l
Summary
Orthologous to human CRYBG2 (crystallin beta-gamma domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in small intestine adult (RPKM 12.2), colon adult (RPKM 10.2) and 7 other tissues See more
Orthologs
human all
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Genomic context

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See Crybg2 in Genome Data Viewer
Location:
4 D2.3; 4 66.5 cM
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (133788042..133819815)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (134060731..134092504)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_11665 Neighboring gene lin-28 homolog A Neighboring gene zinc finger protein 683 Neighboring gene STARR-positive B cell enhancer ABC_E1658 Neighboring gene STARR-positive B cell enhancer ABC_E9600 Neighboring gene STARR-positive B cell enhancer ABC_E842 Neighboring gene STARR-positive B cell enhancer ABC_E4678 Neighboring gene STARR-positive B cell enhancer ABC_E10264 Neighboring gene CD52 antigen Neighboring gene UBX domain protein 11 Neighboring gene STARR-seq mESC enhancer starr_11667 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:133677585-133677803 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:133680177-133680360

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Cloning and tissue expression of the mouse ortholog of AIM1, a betagamma-crystallin superfamily member. Teichmann U, et al. Mamm Genome, 1998 Sep. PMID 9716656
  2. A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Mural RJ, et al. Science, 2002 May 31. PMID 12040188
  3. Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray. Nishimura M, et al. DNA Res, 2004 Oct 31. PMID 15747579
  4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC183649

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
beta/gamma crystallin domain-containing protein 2
Names
absent in melanoma 1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001162970.1 → NP_001156442.1  beta/gamma crystallin domain-containing protein 2

    See identical proteins and their annotated locations for NP_001156442.1

    Status: VALIDATED

    Source sequence(s)
    AK145690, AL670680, BP759371
    Consensus CDS
    CCDS51323.1
    UniProtKB/TrEMBL
    B2RWW9, B7ZCC2
    Related
    ENSMUSP00000114099.2, ENSMUST00000121391.8
    Conserved Domains (6) summary
    PHA03247
    Location:354 → 607
    PHA03247; large tegument protein UL36; Provisional
    PHA03378
    Location:726 → 858
    PHA03378; EBNA-3B; Provisional
    PRK11901
    Location:262 → 439
    PRK11901; hypothetical protein; Reviewed
    pfam00030
    Location:1024 → 1110
    Crystall; Beta/Gamma crystallin
    cl02528
    Location:842 → 920
    Crystall; Beta/Gamma crystallin
    cl26069
    Location:1384 → 1511
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    133788042..133819815
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006538748.4 → XP_006538811.1  beta/gamma crystallin domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A2I3BQG2, B2RWW9
    Related
    ENSMUSP00000154159.2, ENSMUST00000227683.2
    Conserved Domains (6) summary
    PHA03247
    Location:663 → 916
    PHA03247; large tegument protein UL36; Provisional
    PHA03378
    Location:1035 → 1167
    PHA03378; EBNA-3B; Provisional
    PRK11901
    Location:571 → 748
    PRK11901; hypothetical protein; Reviewed
    pfam00030
    Location:1333 → 1419
    Crystall; Beta/Gamma crystallin
    cl02528
    Location:1151 → 1229
    Crystall; Beta/Gamma crystallin
    cl26069
    Location:1693 → 1820
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

  2. XM_006538750.2 → XP_006538813.1  beta/gamma crystallin domain-containing protein 2 isoform X2

    See identical proteins and their annotated locations for XP_006538813.1

    UniProtKB/TrEMBL
    B2RWW9, B7ZCC2
    Conserved Domains (6) summary
    PHA03247
    Location:354 → 607
    PHA03247; large tegument protein UL36; Provisional
    PHA03378
    Location:726 → 858
    PHA03378; EBNA-3B; Provisional
    PRK11901
    Location:262 → 439
    PRK11901; hypothetical protein; Reviewed
    pfam00030
    Location:1024 → 1110
    Crystall; Beta/Gamma crystallin
    cl02528
    Location:842 → 920
    Crystall; Beta/Gamma crystallin
    cl26069
    Location:1384 → 1511
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

  3. XM_006538751.5 → XP_006538814.1  beta/gamma crystallin domain-containing protein 2 isoform X2

    See identical proteins and their annotated locations for XP_006538814.1

    UniProtKB/TrEMBL
    B2RWW9, B7ZCC2
    Conserved Domains (6) summary
    PHA03247
    Location:354 → 607
    PHA03247; large tegument protein UL36; Provisional
    PHA03378
    Location:726 → 858
    PHA03378; EBNA-3B; Provisional
    PRK11901
    Location:262 → 439
    PRK11901; hypothetical protein; Reviewed
    pfam00030
    Location:1024 → 1110
    Crystall; Beta/Gamma crystallin
    cl02528
    Location:842 → 920
    Crystall; Beta/Gamma crystallin
    cl26069
    Location:1384 → 1511
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

RNA

  1. XR_003954928.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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