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Sel1l3 sel-1 suppressor of lin-12-like 3 (C. elegans) [ Mus musculus (house mouse) ]

Gene ID: 231238, updated on 5-Mar-2024

Summary

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Official Symbol
Sel1l3provided by MGI
Official Full Name
sel-1 suppressor of lin-12-like 3 (C. elegans)provided by MGI
Primary source
MGI:MGI:1916941
See related
Ensembl:ENSMUSG00000029189 AllianceGenome:MGI:1916941
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA0746; 2310045A20Rik
Summary
Predicted to be located in nucleoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; node; and notochord. Orthologous to human SEL1L3 (SEL1L family member 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in cerebellum adult (RPKM 19.0), colon adult (RPKM 18.1) and 18 other tissues See more
Orthologs
human all
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Genomic context

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Location:
5 C1; 5 28.96 cM
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (53264425..53370794, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (53107083..53213452, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 5033403H07 gene Neighboring gene predicted gene, 30301 Neighboring gene STARR-seq mESC enhancer starr_13073 Neighboring gene predicted gene 17182 Neighboring gene solute carrier family 34 (sodium phosphate), member 2 Neighboring gene STARR-seq mESC enhancer starr_13074 Neighboring gene predicted gene, 54298 Neighboring gene predicted gene, 30464 Neighboring gene predicted gene, 30519

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Activin A Determines Steroid Levels and Composition in the Fetal Testis. Whiley PAF, et al. Endocrinology, 2020 Jul 1. PMID 32274496
  2. Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network. Shalom-Barak T, et al. Dev Biol, 2012 Dec 1. PMID 22967998, Free PMC Article
  3. Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord. Tamplin OJ, et al. Dev Biol, 2011 Dec 15. PMID 22008794
  4. Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Lumayag S, et al. Proc Natl Acad Sci U S A, 2013 Feb 5. PMID 23341629, Free PMC Article
  5. Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray. Nishimura M, et al. DNA Res, 2004 Oct 31. PMID 15747579

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein sel-1 homolog 3
Names
sel-1L3
suppressor of lin-12-like protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172710.3 → NP_766298.2  protein sel-1 homolog 3

    See identical proteins and their annotated locations for NP_766298.2

    Status: VALIDATED

    Source sequence(s)
    AK122362, BC094607, BP769904
    Consensus CDS
    CCDS51501.1
    UniProtKB/Swiss-Prot
    E9QPJ6, Q148Y5, Q505D2, Q80TS8, Q8BMN0, Q8BYY3, Q8R0K7
    Related
    ENSMUSP00000031090.7, ENSMUST00000031090.8
    Conserved Domains (4) summary
    smart00671
    Location:801 → 839
    SEL1; Sel1-like repeats
    COG0790
    Location:612 → 853
    TPR; TPR repeat [Signal transduction mechanisms]
    sd00010
    Location:714 → 744
    SLR; SLR repeat [structural motif]
    pfam08238
    Location:736 → 766
    Sel1; Sel1 repeat

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    53264425..53370794 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011240730.2 → XP_011239032.1  protein sel-1 homolog 3 isoform X1

    See identical proteins and their annotated locations for XP_011239032.1

    UniProtKB/Swiss-Prot
    Q80TS8
    Conserved Domains (2) summary
    COG0790
    Location:454 → 695
    TPR; TPR repeat [Signal transduction mechanisms]
    sd00010
    Location:556 → 586
    SLR; SLR repeat [structural motif]
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q80TS8.3 GenPept UniProtKB/Swiss-Prot:Q80TS8

Gene LinkOut

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