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Grsf1 G-rich RNA sequence binding factor 1 [ Mus musculus (house mouse) ]

Gene ID: 231413, updated on 26-Jul-2021

Summary

Official Symbol
Grsf1provided by MGI
Official Full Name
G-rich RNA sequence binding factor 1provided by MGI
Primary source
MGI:MGI:106479
See related
Ensembl:ENSMUSG00000044221
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C80280; D5Wsu31; BB232551; D5Wsu31e
Expression
Ubiquitous expression in adrenal adult (RPKM 66.8), ovary adult (RPKM 32.6) and 28 other tissues See more
Orthologs
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Genomic context

See Grsf1 in Genome Data Viewer
Location:
5 E1; 5 43.85 cM
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (88807092..88824030, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (88659233..88676171, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (89088262..89105196, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 42107 Neighboring gene UTP3 small subunit processome component Neighboring gene RUN and FYVE domain containing 3 Neighboring gene MOB kinase activator 1B Neighboring gene predicted gene 15682 Neighboring gene deoxycytidine kinase

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • B130010H02

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA binding ISO
Inferred from Sequence Orthology
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in mitochondrial nucleoid ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in ribonucleoprotein granule ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001098476.2NP_001091946.1  G-rich sequence factor 1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an alternate 5' terminal exon and initiates translation at an alternate start codon, compared to variant 1. It encodes isoform 2, which is shorter and has a distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AC121541, AC160533, AK077782, AK168385, CK391158
    Consensus CDS
    CCDS51540.1
    UniProtKB/Swiss-Prot
    Q8C5Q4
    UniProtKB/TrEMBL
    E9Q179
    Related
    ENSMUSP00000108860.2, ENSMUST00000113234.8
    Conserved Domains (3) summary
    cd12505
    Location:131204
    RRM2_GRSF1; RNA recognition motif 2 in G-rich sequence factor 1 (GRSF-1) and similar proteins
    cd12730
    Location:31109
    RRM1_GRSF1; RNA recognition motif 1 in G-rich sequence factor 1 (GRSF-1) and similar proteins
    cd12733
    Location:283357
    RRM3_GRSF1; RNA recognition motif 3 in G-rich sequence factor 1 (GRSF-1) and similar proteins
  2. NM_178700.5NP_848815.2  G-rich sequence factor 1 isoform 1

    See identical proteins and their annotated locations for NP_848815.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC121541, AK044889, AK045986, AK077782
    Consensus CDS
    CCDS19404.1
    UniProtKB/Swiss-Prot
    Q8C5Q4
    Related
    ENSMUSP00000077972.6, ENSMUST00000078945.12
    Conserved Domains (4) summary
    COG0724
    Location:155325
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12505
    Location:248321
    RRM2_GRSF1; RNA recognition motif 2 in G-rich sequence factor 1 (GRSF-1) and similar proteins
    cd12730
    Location:148226
    RRM1_GRSF1; RNA recognition motif 1 in G-rich sequence factor 1 (GRSF-1) and similar proteins
    cd12733
    Location:400474
    RRM3_GRSF1; RNA recognition motif 3 in G-rich sequence factor 1 (GRSF-1) and similar proteins

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    88807092..88824030 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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