Format

Send to:

Choose Destination

Thnsl2 threonine synthase-like 2 (bacterial) [ Mus musculus (house mouse) ]

Gene ID: 232078, updated on 23-Jun-2021

Summary

Official Symbol
Thnsl2provided by MGI
Official Full Name
threonine synthase-like 2 (bacterial)provided by MGI
Primary source
MGI:MGI:3041254
See related
Ensembl:ENSMUSG00000054474
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
TSH; TSH2; BC051244
Expression
Biased expression in kidney adult (RPKM 87.1), placenta adult (RPKM 25.3) and 11 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Thnsl2 in Genome Data Viewer
Location:
6; 6 C1
Exon count:
10
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (71105150..71121364, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (71128166..71144380, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (71078392..71094370, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 38826 Neighboring gene ribosomal protein L34, pseudogene 1 Neighboring gene predicted gene, 30391 Neighboring gene predicted gene, 38827

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC59076

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables pyridoxal phosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables pyridoxal phosphate binding IDA
Inferred from Direct Assay
more info
PubMed 
enables serine binding IDA
Inferred from Direct Assay
more info
PubMed 
NOT enables threonine synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
threonine synthase-like 2
NP_001029101.1
NP_848500.3

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033929.2NP_001029101.1  threonine synthase-like 2

    See identical proteins and their annotated locations for NP_001029101.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AI156509, AK165463, BQ042728, CX223060
    Consensus CDS
    CCDS20225.1
    UniProtKB/Swiss-Prot
    Q80W22
    Related
    ENSMUSP00000124423.2, ENSMUST00000160918.8
    Conserved Domains (2) summary
    cd01560
    Location:2463
    Thr-synth_2; Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants, cyanobacteria, ...
    PRK09225
    Location:1453
    PRK09225; threonine synthase; Validated
  2. NM_178413.5NP_848500.3  threonine synthase-like 2

    See identical proteins and their annotated locations for NP_848500.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC154003, AI156509, AK165463, BQ042728, CX223060
    Consensus CDS
    CCDS20225.1
    UniProtKB/Swiss-Prot
    Q80W22
    Related
    ENSMUSP00000073861.8, ENSMUST00000074241.9
    Conserved Domains (2) summary
    cd01560
    Location:2463
    Thr-synth_2; Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants, cyanobacteria, ...
    PRK09225
    Location:1453
    PRK09225; threonine synthase; Validated

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    71105150..71121364 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center