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Gys2 glycogen synthase 2 [ Mus musculus (house mouse) ]

Gene ID: 232493, updated on 2-Oct-2021

Summary

Official Symbol
Gys2provided by MGI
Official Full Name
glycogen synthase 2provided by MGI
Primary source
MGI:MGI:2385254
See related
Ensembl:ENSMUSG00000030244
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
LGS; BC021322
Expression
Biased expression in liver E18 (RPKM 32.0), liver adult (RPKM 14.5) and 7 other tissues See more
Orthologs
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Genomic context

See Gys2 in Genome Data Viewer
Location:
6; 6 G2
Exon count:
18
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (142368338..142418856, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (142422612..142473130, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (142371133..142421629, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene golgi transport 1B Neighboring gene spexin hormone Neighboring gene lactate dehydrogenase B Neighboring gene predicted gene, 38919

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3)  1 citation
  • Chemically induced (ENU) (3) 

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • MGC29379

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables glucose binding ISO
Inferred from Sequence Orthology
more info
 
enables glycogen (starch) synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables glycogen (starch) synthase activity ISO
Inferred from Sequence Orthology
more info
 
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in glycogen biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in glycogen biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in glycogen metabolic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in response to glucose ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cell cortex ISO
Inferred from Sequence Orthology
more info
 
located_in cortical actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in ectoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
glycogen [starch] synthase, liver
Names
glycogen synthase, liver
NP_663547.2
XP_006507020.1
XP_011239885.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145572.2NP_663547.2  glycogen [starch] synthase, liver

    See identical proteins and their annotated locations for NP_663547.2

    Status: VALIDATED

    Source sequence(s)
    AK138992, AW106180, AW259825, BX516187
    Consensus CDS
    CCDS20683.1
    UniProtKB/Swiss-Prot
    Q8VCB3
    Related
    ENSMUSP00000032371.8, ENSMUST00000032371.8
    Conserved Domains (2) summary
    cd03793
    Location:27615
    GT1_Glycogen_synthase_GSY2_like; Glycogen synthase, which is most closely related to the GT1 family of glycosyltransferases, catalyzes the transfer of a glucose molecule from UDP-glucose to a terminal branch of a glycogen molecule, a rate-limit step of glycogen biosynthesis. GSY2, the ...
    pfam05693
    Location:32657
    Glycogen_syn; Glycogen synthase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    142368338..142418856 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006506957.4XP_006507020.1  glycogen [starch] synthase, liver isoform X1

    Conserved Domains (1) summary
    pfam05693
    Location:32659
    Glycogen_syn; Glycogen synthase
  2. XM_011241583.2XP_011239885.1  glycogen [starch] synthase, liver isoform X2

    Conserved Domains (1) summary
    pfam05693
    Location:32355
    Glycogen_syn; Glycogen synthase
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