Format

Send to:

Choose Destination

Atxn2l ataxin 2-like [ Mus musculus (house mouse) ]

Gene ID: 233871, updated on 23-Jun-2021

Summary

Official Symbol
Atxn2lprovided by MGI
Official Full Name
ataxin 2-likeprovided by MGI
Primary source
MGI:MGI:2446242
See related
Ensembl:ENSMUSG00000032637
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
A; A2; A2D; A2LG; A2RP; A2lp; Atxnl2
Expression
Ubiquitous expression in testis adult (RPKM 219.2), thymus adult (RPKM 135.9) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Atxn2l in Genome Data Viewer
Location:
7; 7 F3
Exon count:
26
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (126090880..126106991, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (126491708..126507819, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (133635222..133646816, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 46001 Neighboring gene Tu translation elongation factor, mitochondrial Neighboring gene RIKEN cDNA 4930456A14 gene Neighboring gene eukaryotic translation initiation factor 3, subunit C Neighboring gene predicted gene, 24596 Neighboring gene predicted gene, 25579

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in stress granule assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in stress granule assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytoplasmic stress granule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasmic stress granule ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ataxin-2-like protein
Names
ataxin 2 related protein

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001347658.1NP_001334587.1  ataxin-2-like protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC125322
    Consensus CDS
    CCDS85413.1
    UniProtKB/TrEMBL
    Q3TGG2
    Related
    ENSMUSP00000132959.2, ENSMUST00000167759.8
  2. NM_001361487.1NP_001348416.1  ataxin-2-like protein isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC125322
    Conserved Domains (4) summary
    pfam06741
    Location:262324
    LsmAD; LsmAD domain
    pfam14438
    Location:121194
    SM-ATX; Ataxin 2 SM domain
    cl25764
    Location:749950
    PAT1; Topoisomerase II-associated protein PAT1
    cl26464
    Location:334940
    Atrophin-1; Atrophin-1 family
  3. NM_183020.2NP_898841.1  ataxin-2-like protein isoform 1

    See identical proteins and their annotated locations for NP_898841.1

    Status: VALIDATED

    Source sequence(s)
    AC125322, BC054483
    Consensus CDS
    CCDS21831.1
    UniProtKB/Swiss-Prot
    Q7TQH0
    Related
    ENSMUSP00000035415.9, ENSMUST00000040202.15
    Conserved Domains (2) summary
    pfam06741
    Location:262324
    LsmAD; LsmAD domain
    pfam14438
    Location:120188
    SM-ATX; Ataxin 2 SM domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    126090880..126106991 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006507725.3XP_006507788.1  ataxin-2-like protein isoform X5

    UniProtKB/Swiss-Prot
    Q7TQH0
    Conserved Domains (4) summary
    PHA03247
    Location:334940
    PHA03247; large tegument protein UL36; Provisional
    pfam06741
    Location:262324
    LsmAD; LsmAD domain
    pfam09770
    Location:8301035
    PAT1; Topoisomerase II-associated protein PAT1
    pfam14438
    Location:118194
    SM-ATX; Ataxin 2 SM domain
  2. XM_030242516.2XP_030098376.1  ataxin-2-like protein isoform X4

    Conserved Domains (5) summary
    PHA03247
    Location:5471073
    PHA03247; large tegument protein UL36; Provisional
    COG5180
    Location:207532
    PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
    pfam06741
    Location:262324
    LsmAD; LsmAD domain
    pfam09770
    Location:749950
    PAT1; Topoisomerase II-associated protein PAT1
    pfam14438
    Location:118194
    SM-ATX; Ataxin 2 SM domain
  3. XM_006507721.3XP_006507784.1  ataxin-2-like protein isoform X2

    UniProtKB/TrEMBL
    A0A0U1RPL0
    Related
    ENSMUSP00000146023.2, ENSMUST00000206577.2
    Conserved Domains (5) summary
    PHA03247
    Location:5881031
    PHA03247; large tegument protein UL36; Provisional
    COG5180
    Location:207532
    PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
    pfam06741
    Location:262324
    LsmAD; LsmAD domain
    pfam09770
    Location:749950
    PAT1; Topoisomerase II-associated protein PAT1
    pfam14438
    Location:118194
    SM-ATX; Ataxin 2 SM domain
  4. XM_006507723.3XP_006507786.1  ataxin-2-like protein isoform X3

    See identical proteins and their annotated locations for XP_006507786.1

    Conserved Domains (4) summary
    PHA03247
    Location:401946
    PHA03247; large tegument protein UL36; Provisional
    pfam06741
    Location:262324
    LsmAD; LsmAD domain
    pfam09770
    Location:755956
    PAT1; Topoisomerase II-associated protein PAT1
    pfam14438
    Location:118194
    SM-ATX; Ataxin 2 SM domain
  5. XM_006507722.3XP_006507785.1  ataxin-2-like protein isoform X3

    See identical proteins and their annotated locations for XP_006507785.1

    Conserved Domains (4) summary
    PHA03247
    Location:401946
    PHA03247; large tegument protein UL36; Provisional
    pfam06741
    Location:262324
    LsmAD; LsmAD domain
    pfam09770
    Location:755956
    PAT1; Topoisomerase II-associated protein PAT1
    pfam14438
    Location:118194
    SM-ATX; Ataxin 2 SM domain
  6. XM_006507720.4XP_006507783.1  ataxin-2-like protein isoform X1

    See identical proteins and their annotated locations for XP_006507783.1

    Conserved Domains (4) summary
    PHA03247
    Location:401946
    PHA03247; large tegument protein UL36; Provisional
    pfam06741
    Location:262324
    LsmAD; LsmAD domain
    pfam09770
    Location:755956
    PAT1; Topoisomerase II-associated protein PAT1
    pfam14438
    Location:118194
    SM-ATX; Ataxin 2 SM domain
  7. XM_011241775.2XP_011240077.1  ataxin-2-like protein isoform X1

    See identical proteins and their annotated locations for XP_011240077.1

    Conserved Domains (4) summary
    PHA03247
    Location:401946
    PHA03247; large tegument protein UL36; Provisional
    pfam06741
    Location:262324
    LsmAD; LsmAD domain
    pfam09770
    Location:755956
    PAT1; Topoisomerase II-associated protein PAT1
    pfam14438
    Location:118194
    SM-ATX; Ataxin 2 SM domain
  8. XM_006507728.3XP_006507791.1  ataxin-2-like protein isoform X17

    Conserved Domains (2) summary
    PHA03247
    Location:3499
    PHA03247; large tegument protein UL36; Provisional
    PRK14971
    Location:427502
    PRK14971; DNA polymerase III subunit gamma/tau
  9. XM_030242522.2XP_030098382.1  ataxin-2-like protein isoform X11

    Conserved Domains (4) summary
    PHA03247
    Location:248854
    PHA03247; large tegument protein UL36; Provisional
    pfam06741
    Location:176238
    LsmAD; LsmAD domain
    pfam09770
    Location:663864
    PAT1; Topoisomerase II-associated protein PAT1
    pfam14438
    Location:32108
    SM-ATX; Ataxin 2 SM domain
  10. XM_030242521.2XP_030098381.1  ataxin-2-like protein isoform X11

    Conserved Domains (4) summary
    PHA03247
    Location:248854
    PHA03247; large tegument protein UL36; Provisional
    pfam06741
    Location:176238
    LsmAD; LsmAD domain
    pfam09770
    Location:663864
    PAT1; Topoisomerase II-associated protein PAT1
    pfam14438
    Location:32108
    SM-ATX; Ataxin 2 SM domain
  11. XM_030242519.2XP_030098379.1  ataxin-2-like protein isoform X9

    Conserved Domains (5) summary
    PHA03247
    Location:248854
    PHA03247; large tegument protein UL36; Provisional
    PRK07764
    Location:7821006
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    pfam06741
    Location:176238
    LsmAD; LsmAD domain
    pfam09770
    Location:663864
    PAT1; Topoisomerase II-associated protein PAT1
    pfam14438
    Location:32108
    SM-ATX; Ataxin 2 SM domain
  12. XM_030242520.2XP_030098380.1  ataxin-2-like protein isoform X10

    Conserved Domains (3) summary
    PHA03247
    Location:315860
    PHA03247; large tegument protein UL36; Provisional
    pfam06741
    Location:176238
    LsmAD; LsmAD domain
    pfam14438
    Location:35108
    SM-ATX; Ataxin 2 SM domain
  13. XM_036153014.1XP_036008907.1  ataxin-2-like protein isoform X10

    Conserved Domains (3) summary
    PHA03247
    Location:315860
    PHA03247; large tegument protein UL36; Provisional
    pfam06741
    Location:176238
    LsmAD; LsmAD domain
    pfam14438
    Location:35108
    SM-ATX; Ataxin 2 SM domain
  14. XM_030242518.2XP_030098378.1  ataxin-2-like protein isoform X8

    Conserved Domains (4) summary
    PHA03247
    Location:315860
    PHA03247; large tegument protein UL36; Provisional
    pfam06741
    Location:176238
    LsmAD; LsmAD domain
    pfam09770
    Location:669870
    PAT1; Topoisomerase II-associated protein PAT1
    pfam14438
    Location:32108
    SM-ATX; Ataxin 2 SM domain
  15. XM_030242527.1XP_030098387.1  ataxin-2-like protein isoform X17

    Conserved Domains (2) summary
    PHA03247
    Location:3499
    PHA03247; large tegument protein UL36; Provisional
    PRK14971
    Location:427502
    PRK14971; DNA polymerase III subunit gamma/tau
  16. XM_017322209.2XP_017177698.1  ataxin-2-like protein isoform X13

    Conserved Domains (4) summary
    PHA03247
    Location:281826
    PHA03247; large tegument protein UL36; Provisional
    pfam06741
    Location:142204
    LsmAD; LsmAD domain
    pfam09770
    Location:635836
    PAT1; Topoisomerase II-associated protein PAT1
    pfam14438
    Location:174
    SM-ATX; Ataxin 2 SM domain
  17. XM_030242526.2XP_030098386.1  ataxin-2-like protein isoform X16

    Related
    ENSMUSP00000125881.3, ENSMUST00000166682.9
    Conserved Domains (4) summary
    PHA03247
    Location:214820
    PHA03247; large tegument protein UL36; Provisional
    pfam06741
    Location:142204
    LsmAD; LsmAD domain
    pfam09770
    Location:710915
    PAT1; Topoisomerase II-associated protein PAT1
    pfam14438
    Location:174
    SM-ATX; Ataxin 2 SM domain
  18. XM_030242524.1XP_030098384.1  ataxin-2-like protein isoform X14

    Conserved Domains (4) summary
    PHA03247
    Location:214820
    PHA03247; large tegument protein UL36; Provisional
    pfam06741
    Location:142204
    LsmAD; LsmAD domain
    pfam09770
    Location:629830
    PAT1; Topoisomerase II-associated protein PAT1
    pfam14438
    Location:174
    SM-ATX; Ataxin 2 SM domain
  19. XM_030242523.2XP_030098383.1  ataxin-2-like protein isoform X12

    Conserved Domains (4) summary
    PHA03247
    Location:248854
    PHA03247; large tegument protein UL36; Provisional
    pfam06741
    Location:176238
    LsmAD; LsmAD domain
    pfam09770
    Location:663864
    PAT1; Topoisomerase II-associated protein PAT1
    pfam14438
    Location:32108
    SM-ATX; Ataxin 2 SM domain
  20. XM_030242517.1XP_030098377.1  ataxin-2-like protein isoform X7

    Conserved Domains (4) summary
    PHA03247
    Location:277883
    PHA03247; large tegument protein UL36; Provisional
    pfam06741
    Location:205267
    LsmAD; LsmAD domain
    pfam09770
    Location:692893
    PAT1; Topoisomerase II-associated protein PAT1
    pfam14438
    Location:61137
    SM-ATX; Ataxin 2 SM domain
  21. XM_030242525.2XP_030098385.1  ataxin-2-like protein isoform X15

    Conserved Domains (4) summary
    PHA03247
    Location:315860
    PHA03247; large tegument protein UL36; Provisional
    pfam06741
    Location:176238
    LsmAD; LsmAD domain
    pfam09770
    Location:790957
    PAT1; Topoisomerase II-associated protein PAT1
    pfam14438
    Location:32108
    SM-ATX; Ataxin 2 SM domain
  22. XM_036153013.1XP_036008906.1  ataxin-2-like protein isoform X6

    Conserved Domains (3) summary
    PHA03247
    Location:344889
    PHA03247; large tegument protein UL36; Provisional
    pfam06741
    Location:205267
    LsmAD; LsmAD domain
    pfam14438
    Location:64137
    SM-ATX; Ataxin 2 SM domain
  23. XM_036153015.1XP_036008908.1  ataxin-2-like protein isoform X17

    Conserved Domains (2) summary
    PHA03247
    Location:3499
    PHA03247; large tegument protein UL36; Provisional
    PRK14971
    Location:427502
    PRK14971; DNA polymerase III subunit gamma/tau
Support Center