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Ndrg4 N-myc downstream regulated gene 4 [ Mus musculus (house mouse) ]

Gene ID: 234593, updated on 16-Oct-2021

Summary

Official Symbol
Ndrg4provided by MGI
Official Full Name
N-myc downstream regulated gene 4provided by MGI
Primary source
MGI:MGI:2384590
See related
Ensembl:ENSMUSG00000036564
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ndr4; R74996; SMAP-8; Ndr1-rs; D8Bwg1337e
Expression
Biased expression in frontal lobe adult (RPKM 385.8), cerebellum adult (RPKM 322.6) and 6 other tissues See more
Orthologs
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Genomic context

See Ndrg4 in Genome Data Viewer
Location:
8; 8 D1
Exon count:
20
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (96403602..96441584)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (95676974..95714956)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (98226963..98238856)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 42037 Neighboring gene gem (nuclear organelle) associated protein 8 pseudogene Neighboring gene predicted gene, 51585 Neighboring gene SET domain containing 6 Neighboring gene CCR4-NOT transcription complex, subunit 1 Neighboring gene predicted gene, 26493

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC7067

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in basolateral plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in cell projection membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein NDRG4
Names
N-myc downstream regulated 1, related sequence
N-myc downstream-regulated gene 4 protein
protein Ndr4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195006.2NP_001181935.1  protein NDRG4 isoform A

    See identical proteins and their annotated locations for NP_001181935.1

    Status: VALIDATED

    Source sequence(s)
    AC113951
    Consensus CDS
    CCDS57634.1
    UniProtKB/Swiss-Prot
    Q8BTG7
    Related
    ENSMUSP00000072883.8, ENSMUST00000073139.14
    Conserved Domains (1) summary
    pfam03096
    Location:8290
    Ndr; Ndr family
  2. NM_001372421.1NP_001359350.1  protein NDRG4 isoform C precursor

    Status: VALIDATED

    Source sequence(s)
    AC113951
    Conserved Domains (1) summary
    pfam03096
    Location:60342
    Ndr; Ndr family
  3. NM_001372423.1NP_001359352.1  protein NDRG4 isoform C precursor

    Status: VALIDATED

    Source sequence(s)
    AC113951
    Consensus CDS
    CCDS90441.1
    Related
    ENSMUSP00000036226.8, ENSMUST00000041318.14
    Conserved Domains (1) summary
    pfam03096
    Location:60342
    Ndr; Ndr family
  4. NM_001372425.1NP_001359354.1  protein NDRG4 isoform D precursor

    Status: VALIDATED

    Source sequence(s)
    AC113951
    Conserved Domains (1) summary
    pfam03096
    Location:60342
    Ndr; Ndr family
  5. NM_001372426.1NP_001359355.1  protein NDRG4 isoform D precursor

    Status: VALIDATED

    Source sequence(s)
    AC113951
    Conserved Domains (1) summary
    pfam03096
    Location:60342
    Ndr; Ndr family
  6. NM_001372427.1NP_001359356.1  protein NDRG4 isoform E

    Status: VALIDATED

    Source sequence(s)
    AC113951
    Conserved Domains (1) summary
    pfam03096
    Location:40322
    Ndr; Ndr family
  7. NM_001372428.1NP_001359357.1  protein NDRG4 isoform E

    Status: VALIDATED

    Source sequence(s)
    AC113951
    Conserved Domains (1) summary
    pfam03096
    Location:40322
    Ndr; Ndr family
  8. NM_001372429.1NP_001359358.1  protein NDRG4 isoform F

    Status: VALIDATED

    Source sequence(s)
    AC113951
    Conserved Domains (1) summary
    pfam03096
    Location:40322
    Ndr; Ndr family
  9. NM_001372430.1NP_001359359.1  protein NDRG4 isoform G

    Status: VALIDATED

    Source sequence(s)
    AC113951
    Conserved Domains (1) summary
    pfam03096
    Location:40306
    Ndr; Ndr family
  10. NM_001372431.1NP_001359360.1  protein NDRG4 isoform H

    Status: VALIDATED

    Source sequence(s)
    AC113951
    Conserved Domains (1) summary
    pfam03096
    Location:8289
    Ndr; Ndr family
  11. NM_001372432.1NP_001359361.1  protein NDRG4 isoform I

    Status: VALIDATED

    Source sequence(s)
    AC113951
    Conserved Domains (1) summary
    pfam03096
    Location:8289
    Ndr; Ndr family
  12. NM_001372433.1NP_001359362.1  protein NDRG4 isoform J

    Status: VALIDATED

    Source sequence(s)
    AC113951
    Conserved Domains (1) summary
    pfam03096
    Location:8274
    Ndr; Ndr family
  13. NM_001372434.1NP_001359363.1  protein NDRG4 isoform K

    Status: VALIDATED

    Source sequence(s)
    AC113951
    Conserved Domains (1) summary
    pfam03096
    Location:8269
    Ndr; Ndr family
  14. NM_001372435.1NP_001359364.1  protein NDRG4 isoform L

    Status: VALIDATED

    Source sequence(s)
    AC113951
    Conserved Domains (1) summary
    pfam03096
    Location:8261
    Ndr; Ndr family
  15. NM_145602.4NP_663577.1  protein NDRG4 isoform B

    See identical proteins and their annotated locations for NP_663577.1

    Status: VALIDATED

    Source sequence(s)
    AC113951
    Consensus CDS
    CCDS22565.1
    UniProtKB/Swiss-Prot
    Q8BTG7
    Related
    ENSMUSP00000079495.8, ENSMUST00000080666.8
    Conserved Domains (1) summary
    pfam03096
    Location:8290
    Ndr; Ndr family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    96403602..96441584
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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