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PIGN phosphatidylinositol glycan anchor biosynthesis class N [ Homo sapiens (human) ]

Gene ID: 23556, updated on 3-Apr-2024

Summary

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Official Symbol
PIGNprovided by HGNC
Official Full Name
phosphatidylinositol glycan anchor biosynthesis class Nprovided by HGNC
Primary source
HGNC:HGNC:8967
See related
Ensembl:ENSG00000197563 MIM:606097; AllianceGenome:HGNC:8967
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MCD4; MDC4; MCAHS; PIG-N; MCAHS1
Summary
This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is expressed in the endoplasmic reticulum and transfers phosphoethanolamine (EtNP) to the first mannose of the GPI anchor. Two alternatively spliced variants, which encode an identical isoform, have been reported. [provided by RefSeq, Jul 2008]
Expression
Ubiquitous expression in esophagus (RPKM 8.5), thyroid (RPKM 7.2) and 25 other tissues See more
Orthologs
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Genomic context

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Location:
18q21.33
Exon count:
34
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 18 NC_000018.10 (62017615..62187056, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 18 NC_060942.1 (62220799..62389993, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (59708397..59854289, complement)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105372159 Neighboring gene uncharacterized LOC112268209 Neighboring gene Sharpr-MPRA regulatory region 15585 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9501 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_48468 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_48472 Neighboring gene ribose 5-phosphate isomerase A pseudogene 1 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:59667958-59668797 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:59668798-59669636 Neighboring gene Sharpr-MPRA regulatory region 1275 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_48670 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_48690 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_48726/48728 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_48738 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_48746 Neighboring gene ReSE screen-validated silencer GRCh37_chr18:59853791-59854003 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13429 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9502 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_48887 Neighboring gene RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9503 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_48897 Neighboring gene ReSE screen-validated silencer GRCh37_chr18:59957531-59957709 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9504 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9505 Neighboring gene TNF receptor superfamily member 11a Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr18:60034196-60034732 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9506 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr18:60041621-60042250

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. PIGN-Related Disease in Two Lithuanian Families: A Report of Two Novel Pathogenic Variants, Molecular and Clinical Characterisation. Siavrienė E, et al. Medicina (Kaunas), 2022 Oct 26. PMID 36363484, Free PMC Article
  2. Biallelic variants in PIGN cause Fryns syndrome, multiple congenital anomalies-hypotonia-seizures syndrome, and neurologic phenotypes: A genotype-phenotype correlation study. Loong L, et al. Genet Med, 2023 Jan. PMID 36322149
  3. PIGN spatiotemporally regulates the spindle assembly checkpoint proteins in leukemia transformation and progression. Teye EK, et al. Sci Rep, 2021 Sep 24. PMID 34561473, Free PMC Article
  4. Novel insights into the clinico-radiological spectrum of phenotypes associated to PIGN mutations. De Giorgis V, et al. Eur J Paediatr Neurol, 2021 Jul. PMID 34051595
  5. Recessive loss of function PIGN alleles, including an intragenic deletion with founder effect in La Réunion Island, in patients with Fryns syndrome. Alessandri JL, et al. Eur J Hum Genet, 2018 Mar. PMID 29330547, Free PMC Article

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. PIGN-Related Disease in Two Lithuanian Families: A Report of Two Novel Pathogenic Variants, Molecular and Clinical Characterisation.
    Title: PIGN-Related Disease in Two Lithuanian Families: A Report of Two Novel Pathogenic Variants, Molecular and Clinical Characterisation.
  2. Biallelic variants in PIGN cause Fryns syndrome, multiple congenital anomalies-hypotonia-seizures syndrome, and neurologic phenotypes: A genotype-phenotype correlation study.
    Title: Biallelic variants in PIGN cause Fryns syndrome, multiple congenital anomalies-hypotonia-seizures syndrome, and neurologic phenotypes: A genotype-phenotype correlation study.
  3. PIGN spatiotemporally regulates the spindle assembly checkpoint proteins in leukemia transformation and progression.
    Title: PIGN spatiotemporally regulates the spindle assembly checkpoint proteins in leukemia transformation and progression.
  4. Novel insights into the clinico-radiological spectrum of phenotypes associated to PIGN mutations.
    Title: Novel insights into the clinico-radiological spectrum of phenotypes associated to PIGN mutations.
  5. Loss of function PIGN alleles causes Fryns syndrome. Founder effect for PIGN intragenic deletion is observed in La Reunion and other Indian Ocean islands.
    Title: Recessive loss of function PIGN alleles, including an intragenic deletion with founder effect in La Réunion Island, in patients with Fryns syndrome.
  6. PIGN is a novel biomarker of CIN and leukemic transformation/progression in a subgroup of patients with MDS or AML-MRC.
    Title: PIGN gene expression aberration is associated with genomic instability and leukemic progression in acute myeloid leukemia with myelodysplastic features.
  7. Study reports compound heterozygous mutations in PIGN in two siblings with Fryns syndrome, and a homozygous mutation in an unrelated affected individual. However, two further individuals with Fryns syndrome did not carry mutations in this gene, suggesting genetic heterogeneity in this syndrome.
    Title: Fryns Syndrome Associated with Recessive Mutations in PIGN in two Separate Families.
  8. Disease associated mutation L311W reduces enzymatic activity rather than affecting protein levels.
    Title: Analysis of exome data for 4293 trios suggests GPI-anchor biogenesis defects are a rare cause of developmental disorders.
  9. PIGN-1/PIGN is required for quality control in Caenorhabditis elegans and in mammalian cells.
    Title: PIGN prevents protein aggregation in the endoplasmic reticulum independently of its function in the GPI synthesis.
  10. PIGN mutation is associated with multiple congenital anomalies hypotonia seizures syndrome related epilepsy.
    Title: Genotype-phenotype correlation of congenital anomalies in multiple congenital anomalies hypotonia seizures syndrome (MCAHS1)/PIGN-related epilepsy.
Submit: New GeneRIF Correction See all GeneRIFs (16)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Multiple congenital anomalies-hypotonia-seizures syndrome 1
MedGen: C3279775 OMIM: 614080 GeneReviews: Not available
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Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC26427

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables mannose-ethanolamine phosphotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables mannose-ethanolamine phosphotransferase activity TAS
Traceable Author Statement
more info
  
Process Evidence Code Pubs
involved_in GPI anchor biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in preassembly of GPI anchor in ER membrane TAS
Traceable Author Statement
more info
  
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum membrane TAS
Traceable Author Statement
more info
  
located_in membrane HDA PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
  

General protein information

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Preferred Names
GPI ethanolamine phosphate transferase 1
Names
MCD4 homolog
phosphatidylinositol-glycan biosynthesis class N protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_033144.2 RefSeqGene

    Range
    5000..150892
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_012327.6 → NP_036459.1  GPI ethanolamine phosphate transferase 1

    See identical proteins and their annotated locations for NP_036459.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform.
    Source sequence(s)
    AC090354, AC090396, FP340563
    Consensus CDS
    CCDS45879.1
    UniProtKB/Swiss-Prot
    O95427, Q7L8F8, Q8TC01, Q9NT05
    UniProtKB/TrEMBL
    B2RCI8
    Related
    ENSP00000383188.2, ENST00000400334.7
    Conserved Domains (3) summary
    COG1524
    Location:7 → 280
    Npp1; Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily [General function prediction only]
    pfam04987
    Location:431 → 884
    PigN; Phosphatidylinositolglycan class N (PIG-N)
    cd16020
    Location:40 → 345
    GPI_EPT_1; GPI ethanolamine phosphate transferase 1; PIG-N

  2. NM_176787.5 → NP_789744.1  GPI ethanolamine phosphate transferase 1

    See identical proteins and their annotated locations for NP_789744.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longer variant. Variants 1 and 2 encode the same isoform.
    Source sequence(s)
    AC090354, AC090396, FP340563
    Consensus CDS
    CCDS45879.1
    UniProtKB/Swiss-Prot
    O95427, Q7L8F8, Q8TC01, Q9NT05
    UniProtKB/TrEMBL
    B2RCI8
    Related
    ENSP00000492233.1, ENST00000640252.2
    Conserved Domains (3) summary
    COG1524
    Location:7 → 280
    Npp1; Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily [General function prediction only]
    pfam04987
    Location:431 → 884
    PigN; Phosphatidylinositolglycan class N (PIG-N)
    cd16020
    Location:40 → 345
    GPI_EPT_1; GPI ethanolamine phosphate transferase 1; PIG-N

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p14 Primary Assembly

    Range
    62017615..62187056 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047437461.1 → XP_047293417.1  GPI ethanolamine phosphate transferase 1 isoform X12

  2. XM_047437431.1 → XP_047293387.1  GPI ethanolamine phosphate transferase 1 isoform X4

    Related
    ENSP00000491963.1, ENST00000638424.1

  3. XM_047437439.1 → XP_047293395.1  GPI ethanolamine phosphate transferase 1 isoform X6

    UniProtKB/Swiss-Prot
    O95427, Q7L8F8, Q8TC01, Q9NT05
    Related
    ENSP00000492592.1, ENST00000638936.1

  4. XM_011525894.2 → XP_011524196.1  GPI ethanolamine phosphate transferase 1 isoform X1

    See identical proteins and their annotated locations for XP_011524196.1

    UniProtKB/TrEMBL
    A0A1W2PQA9, B2RCI8
    Conserved Domains (3) summary
    COG1524
    Location:7 → 280
    Npp1; Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily [General function prediction only]
    pfam04987
    Location:431 → 884
    PigN; Phosphatidylinositolglycan class N (PIG-N)
    cd16020
    Location:40 → 345
    GPI_EPT_1; GPI ethanolamine phosphate transferase 1; PIG-N

  5. XM_047437440.1 → XP_047293396.1  GPI ethanolamine phosphate transferase 1 isoform X6

    UniProtKB/Swiss-Prot
    O95427, Q7L8F8, Q8TC01, Q9NT05

  6. XM_011525891.2 → XP_011524193.1  GPI ethanolamine phosphate transferase 1 isoform X1

    See identical proteins and their annotated locations for XP_011524193.1

    UniProtKB/TrEMBL
    A0A1W2PQA9, B2RCI8
    Conserved Domains (3) summary
    COG1524
    Location:7 → 280
    Npp1; Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily [General function prediction only]
    pfam04987
    Location:431 → 884
    PigN; Phosphatidylinositolglycan class N (PIG-N)
    cd16020
    Location:40 → 345
    GPI_EPT_1; GPI ethanolamine phosphate transferase 1; PIG-N

  7. XM_047437438.1 → XP_047293394.1  GPI ethanolamine phosphate transferase 1 isoform X6

    UniProtKB/Swiss-Prot
    O95427, Q7L8F8, Q8TC01, Q9NT05

  8. XM_047437459.1 → XP_047293415.1  GPI ethanolamine phosphate transferase 1 isoform X10

    UniProtKB/TrEMBL
    A0A1W2PPR7
    Related
    ENSP00000491549.1, ENST00000638167.1

  9. XM_047437452.1 → XP_047293408.1  GPI ethanolamine phosphate transferase 1 isoform X8

  10. XM_047437435.1 → XP_047293391.1  GPI ethanolamine phosphate transferase 1 isoform X6

    UniProtKB/Swiss-Prot
    O95427, Q7L8F8, Q8TC01, Q9NT05
    Related
    ENSP00000491628.1, ENST00000640876.1

  11. XM_047437433.1 → XP_047293389.1  GPI ethanolamine phosphate transferase 1 isoform X2

  12. XM_011525895.2 → XP_011524197.1  GPI ethanolamine phosphate transferase 1 isoform X1

    See identical proteins and their annotated locations for XP_011524197.1

    UniProtKB/TrEMBL
    A0A1W2PQA9, B2RCI8
    Related
    ENSP00000491620.1, ENST00000640540.1
    Conserved Domains (3) summary
    COG1524
    Location:7 → 280
    Npp1; Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily [General function prediction only]
    pfam04987
    Location:431 → 884
    PigN; Phosphatidylinositolglycan class N (PIG-N)
    cd16020
    Location:40 → 345
    GPI_EPT_1; GPI ethanolamine phosphate transferase 1; PIG-N

  13. XM_047437458.1 → XP_047293414.1  GPI ethanolamine phosphate transferase 1 isoform X10

    UniProtKB/TrEMBL
    A0A1W2PPR7

  14. XM_047437451.1 → XP_047293407.1  GPI ethanolamine phosphate transferase 1 isoform X8

  15. XM_047437436.1 → XP_047293392.1  GPI ethanolamine phosphate transferase 1 isoform X6

    UniProtKB/Swiss-Prot
    O95427, Q7L8F8, Q8TC01, Q9NT05
    Related
    ENSP00000350263.4, ENST00000357637.10

  16. XM_047437434.1 → XP_047293390.1  GPI ethanolamine phosphate transferase 1 isoform X2

  17. XM_011525893.2 → XP_011524195.1  GPI ethanolamine phosphate transferase 1 isoform X1

    See identical proteins and their annotated locations for XP_011524195.1

    UniProtKB/TrEMBL
    A0A1W2PQA9, B2RCI8
    Conserved Domains (3) summary
    COG1524
    Location:7 → 280
    Npp1; Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily [General function prediction only]
    pfam04987
    Location:431 → 884
    PigN; Phosphatidylinositolglycan class N (PIG-N)
    cd16020
    Location:40 → 345
    GPI_EPT_1; GPI ethanolamine phosphate transferase 1; PIG-N

  18. XM_047437456.1 → XP_047293412.1  GPI ethanolamine phosphate transferase 1 isoform X10

    UniProtKB/TrEMBL
    A0A1W2PPR7

  19. XM_047437455.1 → XP_047293411.1  GPI ethanolamine phosphate transferase 1 isoform X9

  20. XM_047437453.1 → XP_047293409.1  GPI ethanolamine phosphate transferase 1 isoform X8

  21. XM_047437432.1 → XP_047293388.1  GPI ethanolamine phosphate transferase 1 isoform X2

  22. XM_011525892.2 → XP_011524194.1  GPI ethanolamine phosphate transferase 1 isoform X1

    See identical proteins and their annotated locations for XP_011524194.1

    UniProtKB/TrEMBL
    A0A1W2PQA9, B2RCI8
    Related
    ENSP00000490965.1, ENST00000639902.1
    Conserved Domains (3) summary
    COG1524
    Location:7 → 280
    Npp1; Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily [General function prediction only]
    pfam04987
    Location:431 → 884
    PigN; Phosphatidylinositolglycan class N (PIG-N)
    cd16020
    Location:40 → 345
    GPI_EPT_1; GPI ethanolamine phosphate transferase 1; PIG-N

  23. XM_047437454.1 → XP_047293410.1  GPI ethanolamine phosphate transferase 1 isoform X10

    UniProtKB/TrEMBL
    A0A1W2PPR7

  24. XM_047437450.1 → XP_047293406.1  GPI ethanolamine phosphate transferase 1 isoform X9

  25. XM_017025685.2 → XP_016881174.1  GPI ethanolamine phosphate transferase 1 isoform X8

    UniProtKB/TrEMBL
    A0A1W2PQP4

  26. XM_011525896.2 → XP_011524198.1  GPI ethanolamine phosphate transferase 1 isoform X2

    UniProtKB/TrEMBL
    B2RCI8
    Conserved Domains (3) summary
    COG1524
    Location:7 → 280
    Npp1; Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily [General function prediction only]
    pfam04987
    Location:431 → 884
    PigN; Phosphatidylinositolglycan class N (PIG-N)
    cd16020
    Location:40 → 345
    GPI_EPT_1; GPI ethanolamine phosphate transferase 1; PIG-N

  27. XM_011525889.2 → XP_011524191.1  GPI ethanolamine phosphate transferase 1 isoform X1

    See identical proteins and their annotated locations for XP_011524191.1

    UniProtKB/TrEMBL
    A0A1W2PQA9, B2RCI8
    Conserved Domains (3) summary
    COG1524
    Location:7 → 280
    Npp1; Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily [General function prediction only]
    pfam04987
    Location:431 → 884
    PigN; Phosphatidylinositolglycan class N (PIG-N)
    cd16020
    Location:40 → 345
    GPI_EPT_1; GPI ethanolamine phosphate transferase 1; PIG-N

  28. XM_047437457.1 → XP_047293413.1  GPI ethanolamine phosphate transferase 1 isoform X10

    UniProtKB/TrEMBL
    A0A1W2PPR7

  29. XM_047437437.1 → XP_047293393.1  GPI ethanolamine phosphate transferase 1 isoform X6

    UniProtKB/Swiss-Prot
    O95427, Q7L8F8, Q8TC01, Q9NT05

  30. XM_011525890.2 → XP_011524192.1  GPI ethanolamine phosphate transferase 1 isoform X1

    See identical proteins and their annotated locations for XP_011524192.1

    UniProtKB/TrEMBL
    A0A1W2PQA9, B2RCI8
    Conserved Domains (3) summary
    COG1524
    Location:7 → 280
    Npp1; Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily [General function prediction only]
    pfam04987
    Location:431 → 884
    PigN; Phosphatidylinositolglycan class N (PIG-N)
    cd16020
    Location:40 → 345
    GPI_EPT_1; GPI ethanolamine phosphate transferase 1; PIG-N

  31. XM_047437449.1 → XP_047293405.1  GPI ethanolamine phosphate transferase 1 isoform X7

    UniProtKB/TrEMBL
    A0A1W2PNR0

  32. XM_047437462.1 → XP_047293418.1  GPI ethanolamine phosphate transferase 1 isoform X11

  33. XM_047437447.1 → XP_047293403.1  GPI ethanolamine phosphate transferase 1 isoform X7

    UniProtKB/TrEMBL
    A0A1W2PNR0

  34. XM_047437464.1 → XP_047293420.1  GPI ethanolamine phosphate transferase 1 isoform X11

  35. XM_047437444.1 → XP_047293400.1  GPI ethanolamine phosphate transferase 1 isoform X7

    UniProtKB/TrEMBL
    A0A1W2PNR0
    Related
    ENSP00000491013.1, ENST00000638183.1

  36. XM_047437448.1 → XP_047293404.1  GPI ethanolamine phosphate transferase 1 isoform X7

    UniProtKB/TrEMBL
    A0A1W2PNR0

  37. XM_047437463.1 → XP_047293419.1  GPI ethanolamine phosphate transferase 1 isoform X11

  38. XM_047437445.1 → XP_047293401.1  GPI ethanolamine phosphate transferase 1 isoform X7

    UniProtKB/TrEMBL
    A0A1W2PNR0

  39. XM_047437441.1 → XP_047293397.1  GPI ethanolamine phosphate transferase 1 isoform X3

  40. XM_047437460.1 → XP_047293416.1  GPI ethanolamine phosphate transferase 1 isoform X11

  41. XM_047437443.1 → XP_047293399.1  GPI ethanolamine phosphate transferase 1 isoform X7

    UniProtKB/TrEMBL
    A0A1W2PNR0

  42. XM_047437446.1 → XP_047293402.1  GPI ethanolamine phosphate transferase 1 isoform X7

    UniProtKB/TrEMBL
    A0A1W2PNR0

  43. XM_047437442.1 → XP_047293398.1  GPI ethanolamine phosphate transferase 1 isoform X3

  44. XM_047437430.1 → XP_047293386.1  GPI ethanolamine phosphate transferase 1 isoform X3

  45. XM_011525898.2 → XP_011524200.1  GPI ethanolamine phosphate transferase 1 isoform X5

    UniProtKB/TrEMBL
    A0A1W2PS19
    Related
    ENSP00000492783.1, ENST00000639174.1
    Conserved Domains (3) summary
    COG1524
    Location:7 → 280
    Npp1; Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily [General function prediction only]
    pfam04987
    Location:431 → 884
    PigN; Phosphatidylinositolglycan class N (PIG-N)
    cd16020
    Location:40 → 345
    GPI_EPT_1; GPI ethanolamine phosphate transferase 1; PIG-N

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060942.1 Alternate T2T-CHM13v2.0

    Range
    62220799..62389993 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054318466.1 → XP_054174441.1  GPI ethanolamine phosphate transferase 1 isoform X12

  2. XM_054318438.1 → XP_054174413.1  GPI ethanolamine phosphate transferase 1 isoform X4

  3. XM_054318446.1 → XP_054174421.1  GPI ethanolamine phosphate transferase 1 isoform X6

  4. XM_054318437.1 → XP_054174412.1  GPI ethanolamine phosphate transferase 1 isoform X2

  5. XM_054318435.1 → XP_054174410.1  GPI ethanolamine phosphate transferase 1 isoform X2

  6. XM_054318445.1 → XP_054174420.1  GPI ethanolamine phosphate transferase 1 isoform X6

  7. XM_054318444.1 → XP_054174419.1  GPI ethanolamine phosphate transferase 1 isoform X6

  8. XM_054318464.1 → XP_054174439.1  GPI ethanolamine phosphate transferase 1 isoform X10

  9. XM_054318457.1 → XP_054174432.1  GPI ethanolamine phosphate transferase 1 isoform X9

  10. XM_054318441.1 → XP_054174416.1  GPI ethanolamine phosphate transferase 1 isoform X6

  11. XM_054318433.1 → XP_054174408.1  GPI ethanolamine phosphate transferase 1 isoform X2

  12. XM_054318463.1 → XP_054174438.1  GPI ethanolamine phosphate transferase 1 isoform X10

  13. XM_054318442.1 → XP_054174417.1  GPI ethanolamine phosphate transferase 1 isoform X6

  14. XM_054318436.1 → XP_054174411.1  GPI ethanolamine phosphate transferase 1 isoform X2

  15. XM_054318461.1 → XP_054174436.1  GPI ethanolamine phosphate transferase 1 isoform X10

  16. XM_054318460.1 → XP_054174435.1  GPI ethanolamine phosphate transferase 1 isoform X9

  17. XM_054318432.1 → XP_054174407.1  GPI ethanolamine phosphate transferase 1 isoform X2

  18. XM_054318458.1 → XP_054174433.1  GPI ethanolamine phosphate transferase 1 isoform X10

  19. XM_054318459.1 → XP_054174434.1  GPI ethanolamine phosphate transferase 1 isoform X9

  20. XM_054318431.1 → XP_054174406.1  GPI ethanolamine phosphate transferase 1 isoform X2

  21. XM_054318462.1 → XP_054174437.1  GPI ethanolamine phosphate transferase 1 isoform X10

  22. XM_054318443.1 → XP_054174418.1  GPI ethanolamine phosphate transferase 1 isoform X6

  23. XM_054318434.1 → XP_054174409.1  GPI ethanolamine phosphate transferase 1 isoform X2

  24. XM_054318469.1 → XP_054174444.1  GPI ethanolamine phosphate transferase 1 isoform X11

  25. XM_054318454.1 → XP_054174429.1  GPI ethanolamine phosphate transferase 1 isoform X7

  26. XM_054318456.1 → XP_054174431.1  GPI ethanolamine phosphate transferase 1 isoform X7

  27. XM_054318471.1 → XP_054174446.1  GPI ethanolamine phosphate transferase 1 isoform X11

  28. XM_054318451.1 → XP_054174426.1  GPI ethanolamine phosphate transferase 1 isoform X7

  29. XM_054318455.1 → XP_054174430.1  GPI ethanolamine phosphate transferase 1 isoform X7

  30. XM_054318470.1 → XP_054174445.1  GPI ethanolamine phosphate transferase 1 isoform X11

  31. XM_054318452.1 → XP_054174427.1  GPI ethanolamine phosphate transferase 1 isoform X7

  32. XM_054318465.1 → XP_054174440.1  GPI ethanolamine phosphate transferase 1 isoform X11

  33. XM_054318447.1 → XP_054174422.1  GPI ethanolamine phosphate transferase 1 isoform X7

  34. XM_054318453.1 → XP_054174428.1  GPI ethanolamine phosphate transferase 1 isoform X7

  35. XM_054318439.1 → XP_054174414.1  GPI ethanolamine phosphate transferase 1 isoform X5

  36. XM_054318468.1 → XP_054174443.1  GPI ethanolamine phosphate transferase 1 isoform X14

  37. XM_054318448.1 → XP_054174423.1  GPI ethanolamine phosphate transferase 1 isoform X13

  38. XM_054318467.1 → XP_054174442.1  GPI ethanolamine phosphate transferase 1 isoform X14

  39. XM_054318449.1 → XP_054174424.1  GPI ethanolamine phosphate transferase 1 isoform X13

  40. XM_054318440.1 → XP_054174415.1  GPI ethanolamine phosphate transferase 1 isoform X13

  41. XM_054318450.1 → XP_054174425.1  GPI ethanolamine phosphate transferase 1 isoform X13

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O95427.1 GenPept UniProtKB/Swiss-Prot:O95427

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